Gene/Proteome Database (LMPD)

LMPD ID
LMP012621
Gene ID
29646
Species
Rattus norvegicus (Rat)
Gene Name
alcohol dehydrogenase 4 (class II), pi polypeptide
Gene Symbol
Adh4
Synonyms
ADH-1; Ac1002;
Alternate Names
alcohol dehydrogenase 4; ADH2; alcohol dehydrogenase II; alcohol dehydrogenase class II; class II alcohol dehydrogenase, pi subunit;
Chromosome
2
Map Location
2q44

Proteins

alcohol dehydrogenase 4
Refseq ID NP_058966
Protein GI 253735823
UniProt ID A1L128
mRNA ID NM_017270
Length 377
MGTQGKVITCKAAIAWKTDSPLCIEEIEVSPPKAHEVRIKVIATCVCPTDINATNPKKKALFPVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKKCKLCLSPLTNLCGKLRNFKYPTIDQELMEDRTSRFTCKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGFTSGYGAAINTAKVTPGSACAVFGLGCVGLSAVIGCKIAGASRIIAIDINSEKFPKAKALGATDCLNPRDLDKPVQDVITELTGGGVDFSLDCAGTAQTLKAAVDCTVVGWGSCTVVGAKVDEMNISTVDMILGRSVKGTFFGGWKSVDSVPNLVTDYKNKKFDLDLLVTHALPFDKINDAIDLMNQGKSIRTILTF

Gene Information

Entrez Gene ID
29646
Gene Name
alcohol dehydrogenase 4 (class II), pi polypeptide
Gene Symbol
Adh4
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0051287 IEA:Ensembl F NAD binding
GO:0003960 IEA:Ensembl F NADPH:quinone reductase activity
GO:0004024 IEA:Ensembl F alcohol dehydrogenase activity, zinc-dependent
GO:0004032 IEA:Ensembl F alditol:NADP+ 1-oxidoreductase activity
GO:0005503 IEA:Ensembl F all-trans retinal binding
GO:0019115 IEA:Ensembl F benzaldehyde dehydrogenase activity
GO:0035276 IEA:InterPro F ethanol binding
GO:0019841 IEA:Ensembl F retinol binding
GO:0004745 IEA:Ensembl F retinol dehydrogenase activity
GO:0008270 IEA:InterPro F zinc ion binding
GO:0046164 IEA:Ensembl P alcohol catabolic process
GO:0006081 IEA:Ensembl P cellular aldehyde metabolic process
GO:0006069 IEA:Ensembl P ethanol oxidation
GO:1901661 IEA:Ensembl P quinone metabolic process
GO:0042572 IEA:Ensembl P retinol metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ko05204 Chemical carcinogenesis
rno05204 Chemical carcinogenesis
ko00982 Drug metabolism - cytochrome P450
rno00982 Drug metabolism - cytochrome P450
ko00071 Fatty acid degradation
rno00071 Fatty acid degradation
ko00010 Glycolysis / Gluconeogenesis
rno00010 Glycolysis / Gluconeogenesis
rno01100 Metabolic pathways
ko00980 Metabolism of xenobiotics by cytochrome P450
rno00980 Metabolism of xenobiotics by cytochrome P450
ko00830 Retinol metabolism
rno00830 Retinol metabolism
ko00350 Tyrosine metabolism
rno00350 Tyrosine metabolism

REACTOME Pathway Links

REACTOME Pathway ID Description
5953258 Biological oxidations
5953325 Ethanol oxidation
5953250 Metabolism
5953326 Phase 1 - Functionalization of compounds

Domain Information

InterPro Annotations

Accession Description
IPR013154 Alcohol dehydrogenase GroES-like
IPR028632 Alcohol dehydrogenase family, zinc-type, class-II subfamily
IPR002085 Alcohol dehydrogenase superfamily, zinc-type
IPR013149 Alcohol dehydrogenase, C-terminal
IPR002328 Alcohol dehydrogenase, zinc-type, conserved site
IPR011032 GroES (chaperonin 10)-like
IPR016040 NAD(P)-binding domain

UniProt Annotations

Entry Information

Gene Name
alcohol dehydrogenase 4 (class II), pi polypeptide
Protein Entry
A1L128_RAT
UniProt ID
A1L128
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP012621 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
253735823 RefSeq NP_058966 377 alcohol dehydrogenase 4

Identical Sequences to LMP012621 proteins

Reference Database Accession Length Protein Name
GI:253735823 GenBank AAI27505.1 377 Alcohol dehydrogenase 4 (class II), pi polypeptide [Rattus norvegicus]

Related Sequences to LMP012621 proteins

Reference Database Accession Length Protein Name
GI:253735823 EMBL CAA62241.1 377 alcohol dehydrogenase [Rattus norvegicus]
GI:253735823 GenBank AAI27505.1 377 Alcohol dehydrogenase 4 (class II), pi polypeptide [Rattus norvegicus]
GI:253735823 SwissProt Q64563.3 377 RecName: Full=Alcohol dehydrogenase 4; AltName: Full=ADH2; AltName: Full=Alcohol dehydrogenase class II; Short=Alcohol dehydrogenase II [Rattus norvegicus]