Gene/Proteome Database (LMPD)

LMPD ID
LMP012644
Gene ID
50682
Species
Rattus norvegicus (Rat)
Gene Name
lipase, gastric
Gene Symbol
Lipf
Synonyms
Rnlp; RNLIP;
Alternate Names
gastric triacylglycerol lipase; GL; lipase F; gastric lipase; lingual lipase; prelingual lipase;
Chromosome
1
Map Location
1q52
EC Number
3.1.1.3
Summary
gastric enzyme; metabolizes lipids and triacylglycerols; may be auxiliary enzyme for fat digestion and absorption [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Lipf

Proteins

gastric triacylglycerol lipase precursor
Refseq ID NP_059037
Protein GI 8394193
UniProt ID P04634
mRNA ID NM_017341
Length 395
MWLLLITSVISTFGGAHGLFGKLGPGNPEANMNISQMITYWGYPCQEYEVVTEDGYILGVYRIPHGKNNSENIGKRPVVYLQHGLIASATNWIANLPNNSLAFMLADAGYDVWLGNSRGNTWSRKNVYYSPDSVEFWAFSFDEMAKYDLPATINFIVQKTGQEKIHYVGHSQGTTIGFIAFSTNPTLAKKIKTFYALAPVATVKYTQSPLKKISFIPTFLFKLMFGKKMFLPHTYFDDFLGTEVCSREVLDLLCSNTLFIFCGFDKKNLNVSRFDVYLGHNPAGTSVQDFLHWAQLVRSGKFQAFNWGSPSQNMLHYNQKTPPEYDVSAMTVPVAVWNGGNDILADPQDVAMLLPKLSNLLFHKEILAYNHLDFIWAMDAPQEVYNEMISMMAED
sig_peptide: 1..18 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1903 peptide sequence: MWLLLITSVISTFGGAHG mat_peptide: 19..395 product: gastric triacylglycerol lipase calculated_mol_wt: 42703 peptide sequence: LFGKLGPGNPEANMNISQMITYWGYPCQEYEVVTEDGYILGVYRIPHGKNNSENIGKRPVVYLQHGLIASATNWIANLPNNSLAFMLADAGYDVWLGNSRGNTWSRKNVYYSPDSVEFWAFSFDEMAKYDLPATINFIVQKTGQEKIHYVGHSQGTTIGFIAFSTNPTLAKKIKTFYALAPVATVKYTQSPLKKISFIPTFLFKLMFGKKMFLPHTYFDDFLGTEVCSREVLDLLCSNTLFIFCGFDKKNLNVSRFDVYLGHNPAGTSVQDFLHWAQLVRSGKFQAFNWGSPSQNMLHYNQKTPPEYDVSAMTVPVAVWNGGNDILADPQDVAMLLPKLSNLLFHKEILAYNHLDFIWAMDAPQEVYNEMISMMAED

Gene Information

Entrez Gene ID
50682
Gene Name
lipase, gastric
Gene Symbol
Lipf
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005576 IEA:UniProtKB-KW C extracellular region
GO:0005739 IDA:MGI C mitochondrion
GO:0016298 TAS:RGD F lipase activity
GO:0016615 IDA:MGI F malate dehydrogenase activity
GO:0004806 IEA:UniProtKB-EC F triglyceride lipase activity
GO:0007586 TAS:RGD P digestion
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process
GO:0006108 IDA:MGI P malate metabolic process
GO:0055114 IDA:GOC P oxidation-reduction process

KEGG Pathway Links

KEGG Pathway ID Description
M00098 Acylglycerol degradation
ko04975 Fat digestion and absorption
rno04975 Fat digestion and absorption
ko00561 Glycerolipid metabolism
rno00561 Glycerolipid metabolism
rno01100 Metabolic pathways

Domain Information

InterPro Annotations

Accession Description
IPR029058 Alpha/Beta hydrolase fold
IPR000073 Alpha/beta hydrolase fold-1
IPR025483 Lipase, eukaryotic
IPR006693 Partial AB-hydrolase lipase domain

UniProt Annotations

Entry Information

Gene Name
lipase, gastric
Protein Entry
LIPG_RAT
UniProt ID
P04634
Species
Rat

Comments

Comment Type Description
Catalytic Activity Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
Similarity Belongs to the AB hydrolase superfamily. Lipase family
Subcellular Location Secreted.
Tissue Specificity Secreted by the serous (von Ebner's) glands at the back of the rat tongue.

Identical and Related Proteins

Unique RefSeq proteins for LMP012644 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
8394193 RefSeq NP_059037 395 gastric triacylglycerol lipase precursor

Identical Sequences to LMP012644 proteins

Reference Database Accession Length Protein Name
GI:8394193 EMBL CAA26179.1 395 unnamed protein product [Rattus norvegicus]
GI:8394193 GenBank EDM13150.1 395 lipase, gastric [Rattus norvegicus]
GI:8394193 GenBank AGN09445.1 395 Sequence 23 from patent US 8445250
GI:8394193 SwissProt P04634.1 395 RecName: Full=Gastric triacylglycerol lipase; Short=GL; Short=Gastric lipase; AltName: Full=Lingual lipase; Flags: Precursor [Rattus norvegicus]

Related Sequences to LMP012644 proteins

Reference Database Accession Length Protein Name
GI:8394193 EMBL CAA26179.1 395 unnamed protein product [Rattus norvegicus]
GI:8394193 GenBank EDM13150.1 395 lipase, gastric [Rattus norvegicus]
GI:8394193 SwissProt P04634.1 395 RecName: Full=Gastric triacylglycerol lipase; Short=GL; Short=Gastric lipase; AltName: Full=Lingual lipase; Flags: Precursor [Rattus norvegicus]