LIPID MAPS

LMPD ID

LMP012654

Gene ID

55939

Species

Rattus norvegicus (Rat)

Gene Name

apolipoprotein M

Gene Symbol

Apom

Alternate Names

apolipoprotein M; apo-M; protein Px;

Chromosome

20

Map Location

20p12

Summary

human homolog is a lipoprotein associated with high density lipoprotein (HDL) particles [RGD, Feb 2006]

Orthologs

View orthologs and multiple alignments for Apom

apolipoprotein M precursor
Refseq ID	NP_062246
Protein GI	9506391
UniProt ID	P14630
mRNA ID	NM_019373
Length	190
MFHQVWAALLYLYGLLFNSMNQCPEHSQLMTLGMDDKETPEPHLGLWYFIAGAAPTMEELATFDQVDNIVFNMAAGSAPRQLQLRATIRTKNGVCVPRKWTYHLTEGKGNTELRTEGRPDMKTDLFSISCPGGIMLKETGQGYQRFLLYNRSPHPPEECVEEFQSLTSCLDFKAFLVTPRNQEACPLSSK
sig_peptide: 1..17 experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (P14630.2) calculated_mol_wt: 2086 peptide sequence: MFHQVWAALLYLYGLLF mat_peptide: 18..190 product: Apolipoprotein M experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (P14630.2) calculated_mol_wt: 19445 peptide sequence: NSMNQCPEHSQLMTLGMDDKETPEPHLGLWYFIAGAAPTMEELATFDQVDNIVFNMAAGSAPRQLQLRATIRTKNGVCVPRKWTYHLTEGKGNTELRTEGRPDMKTDLFSISCPGGIMLKETGQGYQRFLLYNRSPHPPEECVEEFQSLTSCLDFKAFLVTPRNQEACPLSSK

Entrez Gene ID

55939

Gene Name

apolipoprotein M

Gene Symbol

Apom

Species

Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0034365	IEA:Ensembl	C	discoidal high-density lipoprotein particle
GO:0005615	IDA:RGD	C	extracellular space
GO:0070062	IEA:Ensembl	C	extracellular vesicular exosome
GO:0034362	IEA:Ensembl	C	low-density lipoprotein particle
GO:0034366	IEA:Ensembl	C	spherical high-density lipoprotein particle
GO:0034361	IEA:Ensembl	C	very-low-density lipoprotein particle
GO:0016209	IEA:Ensembl	F	antioxidant activity
GO:0005319	IEA:Ensembl	F	lipid transporter activity
GO:0005543	IEA:Ensembl	F	phospholipid binding
GO:0033344	IEA:Ensembl	P	cholesterol efflux
GO:0034380	IEA:Ensembl	P	high-density lipoprotein particle assembly
GO:0034384	IEA:Ensembl	P	high-density lipoprotein particle clearance
GO:0034375	IEA:Ensembl	P	high-density lipoprotein particle remodeling
GO:0042157	IEA:Ensembl	P	lipoprotein metabolic process
GO:0034445	IEA:Ensembl	P	negative regulation of plasma lipoprotein particle oxidation
GO:0009749	IEP:RGD	P	response to glucose
GO:0043691	IEA:Ensembl	P	reverse cholesterol transport

InterPro Annotations

Accession	Description
IPR022734	Apolipoprotein M
IPR012674	Calycin
IPR011038	Calycin-like

Entry Information

Gene Name

apolipoprotein M

Protein Entry

APOM_RAT

UniProt ID

P14630

Species

Rat

Comments

Comment Type	Description
Function	Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid (By similarity)
Similarity	Belongs to the calycin superfamily. Lipocalin family. Highly divergent
Subcellular Location	Secreted. Note=Associated with HDL.
Tissue Specificity	Expressed by the liver; secreted in plasma.

Unique RefSeq proteins for LMP012654 (as displayed in Record Overview)

Protein GI	Database	Accession	Length	Protein Name
9506391	RefSeq	NP_062246	190	apolipoprotein M precursor

Identical Sequences to LMP012654 proteins

Reference	Database	Accession	Length	Protein Name
GI:9506391	EMBL	CAE83996.1	190	apolipoprotein M [Rattus norvegicus]
GI:9506391	GenBank	AAH89807.1	190	Apolipoprotein M [Rattus norvegicus]
GI:9506391	GenBank	EDL83529.1	190	apolipoprotein M [Rattus norvegicus]
GI:9506391	SwissProt	P14630.2	190	RecName: Full=Apolipoprotein M; Short=Apo-M; Short=ApoM; AltName: Full=Protein Px; Flags: Precursor [Rattus norvegicus]

Related Sequences to LMP012654 proteins

Reference	Database	Accession	Length	Protein Name
GI:9506391	EMBL	CAE83996.1	190	apolipoprotein M [Rattus norvegicus]
GI:9506391	GenBank	AAF23408.1	190	apolipoprotein M [Rattus norvegicus]
GI:9506391	GenBank	EDL83529.1	190	apolipoprotein M [Rattus norvegicus]