Gene/Proteome Database (LMPD)
LMPD ID
LMP012709
Gene ID
Species
Rattus norvegicus (Rat)
Gene Name
enoyl CoA hydratase 1, peroxisomal
Gene Symbol
Synonyms
Pxel;
Alternate Names
delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial; Peroxisomal enoyl hydratase-like protein; enoyl hydratase-like protein peroxisomal; enoyl coenzyme A hydratase 1, peroxisomal; enoyl hydratase-like protein, peroxisomal;
Chromosome
1
Map Location
1q21
EC Number
5.3.3.-
Summary
isomerase enzyme that may be involved with the ability of peroxisomes to oxidize long-chain faty acids [RGD, Feb 2006]
Orthologs
Proteins
delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial precursor | |
---|---|
Refseq ID | NP_072116 |
Protein GI | 12018256 |
UniProt ID | Q62651 |
mRNA ID | NM_022594 |
Length | 327 |
MATAMTVSSKLLGLLMQQLRGTRQLYFNVSLRSLSSSAQEASKRIPEEVSDHNYESIQVTSAQKHVLHVQLNRPEKRNAMNRAFWRELVECFQKISKDSDCRAVVVSGAGKMFTSGIDLMDMASDILQPPGDDVARIAWYLRDLISRYQKTFTVIEKCPKPVITAIHGGCIGGGVDLISACDIRYCTQDAFFQVKEVDVGLAADVGTLQRLPKVIGNRSLVNELTFTARKMMADEALDSGLVSRVFPDKDVMLNAAFALAADISSKSPVAVQGSKINLIYSRDHSVDESLDYMATWNMSMLQTQDIIKSVQAAMEKKDSKSITFSKL | |
transit_peptide: 1..33 inference: non-experimental evidence, no additional details recorded note: Mitochondrion (Potential); propagated from UniProtKB/Swiss-Prot (Q62651.2) calculated_mol_wt: 3715 peptide sequence: MATAMTVSSKLLGLLMQQLRGTRQLYFNVSLRS mat_peptide: 34..327 product: Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q62651.2) calculated_mol_wt: 32504 peptide sequence: LSSSAQEASKRIPEEVSDHNYESIQVTSAQKHVLHVQLNRPEKRNAMNRAFWRELVECFQKISKDSDCRAVVVSGAGKMFTSGIDLMDMASDILQPPGDDVARIAWYLRDLISRYQKTFTVIEKCPKPVITAIHGGCIGGGVDLISACDIRYCTQDAFFQVKEVDVGLAADVGTLQRLPKVIGNRSLVNELTFTARKMMADEALDSGLVSRVFPDKDVMLNAAFALAADISSKSPVAVQGSKINLIYSRDHSVDESLDYMATWNMSMLQTQDIIKSVQAAMEKKDSKSITFSKL |
Gene Information
Entrez Gene ID
Gene Name
enoyl CoA hydratase 1, peroxisomal
Gene Symbol
Species
Rattus norvegicus
Gene Ontology (GO Annotations)
GO ID | Source | Type | Description |
---|---|---|---|
GO:0070062 | IEA:Ensembl | C | extracellular vesicular exosome |
GO:0005739 | IDA:UniProtKB | C | mitochondrion |
GO:0005777 | IEA:UniProtKB-KW | C | peroxisome |
GO:0016853 | IEA:UniProtKB-KW | F | isomerase activity |
GO:0046872 | IEA:UniProtKB-KW | F | metal ion binding |
GO:0006635 | IEA:UniProtKB-UniPathway | P | fatty acid beta-oxidation |
KEGG Pathway Links
Domain Information
UniProt Annotations
Entry Information
Comments
Comment Type | Description |
---|---|
Function | Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4- trans-dienoyl-CoA. |
Pathway | Lipid metabolism; fatty acid beta-oxidation. |
Similarity | Belongs to the enoyl-CoA hydratase/isomerase family |
Subcellular Location | Mitochondrion. Peroxisome. |
Subunit | Homohexamer |
Identical and Related Proteins
Unique RefSeq proteins for LMP012709 (as displayed in Record Overview)
Protein GI | Database | Accession | Length | Protein Name |
---|---|---|---|---|
12018256 | RefSeq | NP_072116 | 327 | delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial precursor |
Identical Sequences to LMP012709 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:12018256 | GenBank | AAA82008.1 | 327 | peroxisomal enoyl hydratase-like protein [Rattus norvegicus] |
Related Sequences to LMP012709 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:12018256 | GenBank | AAA82008.1 | 327 | peroxisomal enoyl hydratase-like protein [Rattus norvegicus] |
GI:12018256 | GenBank | EDM07870.1 | 327 | enoyl coenzyme A hydratase 1, peroxisomal [Rattus norvegicus] |
GI:12018256 | SwissProt | Q62651.2 | 327 | RecName: Full=Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial; Flags: Precursor [Rattus norvegicus] |