Gene/Proteome Database (LMPD)
LMPD ID
LMP012739
Gene ID
Species
Rattus norvegicus (Rat)
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class M
Gene Symbol
Synonyms
GPI-MT-I;
Alternate Names
GPI mannosyltransferase 1; GPI mannosyltransferase I; PIG-M mRNA for mannosyltransferase; phosphatidylinositol glycan, class M; phosphatidylinositol-glycan biosynthesis class M protein;
Chromosome
13
Map Location
13q24
EC Number
2.4.1.-
Summary
mannosyltransferase that catalyzes the transfer of the first mannose to glycosylphosphatidylinositol in GPI anchor biosynthesis; activity may be localized to the lumenal side of the endoplasmic reticulum membrane [RGD, Feb 2006]
Orthologs
Proteins
GPI mannosyltransferase 1 | |
---|---|
Refseq ID | NP_077058 |
Protein GI | 13162329 |
UniProt ID | Q9EQY6 |
mRNA ID | NM_024144 |
Length | 423 |
MSYTKHWGEWFLNLRVPPAGVFGVAFLARVALVFYGVFQDRTLLVRYTDIDYHVFTDAARFVTEGRSPYLRATYRYTPLLSWLLTPNVYLSELFGKFLFISCDLLTAFLLYRLLLLKGLGRRQACGYCVFWLLNPLPMAVSSRGNADSIVASLVLTTLYLIEKRLIACAAVFYGFAVHMKMYPVTYILPIALHLRPERDSDEGLRLARYSFQARLYDFLKRLCSWAVLLFVAIAGLTFLALSFGFYYKYGWEFLEHTYLYHLTRRDIRHNFSPYFYMLYLTAESKWSFTLGIAAFLPQFILLSAASFAYYRDLVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVLLMLWFIGQALWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHYKEDRLTERIKYD |
Gene Information
Entrez Gene ID
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class M
Gene Symbol
Species
Rattus norvegicus
Gene Ontology (GO Annotations)
GO ID | Source | Type | Description |
---|---|---|---|
GO:0005789 | IEA:InterPro | C | endoplasmic reticulum membrane |
GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
GO:0000030 | IDA:RGD | F | mannosyltransferase activity |
GO:0006506 | IDA:RGD | P | GPI anchor biosynthetic process |
GO:0097502 | IDA:GOC | P | mannosylation |
KEGG Pathway Links
KEGG Pathway ID | Description |
---|---|
M00065 | GPI-anchor biosynthesis, core oligosaccharide |
ko00563 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
rno00563 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
rno01100 | Metabolic pathways |
REACTOME Pathway Links
Domain Information
InterPro Annotations
Accession | Description |
---|---|
IPR007704 | Mannosyltransferase, DXD |
UniProt Annotations
Entry Information
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class M
Protein Entry
PIGM_RAT
UniProt ID
Species
Rat
Comments
Comment Type | Description |
---|---|
Function | Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly (By similarity) |
Pathway | Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis. |
Similarity | Belongs to the PIGM family |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein . |
Identical and Related Proteins
Unique RefSeq proteins for LMP012739 (as displayed in Record Overview)
Protein GI | Database | Accession | Length | Protein Name |
---|---|---|---|---|
13162329 | RefSeq | NP_077058 | 423 | GPI mannosyltransferase 1 |
Identical Sequences to LMP012739 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:13162329 | DBBJ | BAB18566.1 | 423 | mannosyltransferase [Rattus norvegicus] |
GI:13162329 | GenBank | EDL94711.1 | 423 | phosphatidylinositol glycan, class M [Rattus norvegicus] |
GI:13162329 | RefSeq | XP_008772129.1 | 423 | PREDICTED: GPI mannosyltransferase 1 [Rattus norvegicus] |
GI:13162329 | SwissProt | Q9EQY6.1 | 423 | RecName: Full=GPI mannosyltransferase 1; AltName: Full=GPI mannosyltransferase I; Short=GPI-MT-I; AltName: Full=Phosphatidylinositol-glycan biosynthesis class M protein; Short=PIG-M [Rattus norvegicus] |
Related Sequences to LMP012739 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:13162329 | GenBank | EDL94711.1 | 423 | phosphatidylinositol glycan, class M [Rattus norvegicus] |
GI:13162329 | RefSeq | XP_008772129.1 | 423 | PREDICTED: GPI mannosyltransferase 1 [Rattus norvegicus] |
GI:13162329 | SwissProt | Q9EQY6.1 | 423 | RecName: Full=GPI mannosyltransferase 1; AltName: Full=GPI mannosyltransferase I; Short=GPI-MT-I; AltName: Full=Phosphatidylinositol-glycan biosynthesis class M protein; Short=PIG-M [Rattus norvegicus] |