Gene/Proteome Database (LMPD)

LMPD ID
LMP012862
Gene ID
114553
Species
Rattus norvegicus (Rat)
Gene Name
neutrophil cytosolic factor 1
Gene Symbol
Ncf1
Synonyms
Ncf-1; p47phox;
Alternate Names
neutrophil cytosol factor 1; phagocyte oxidase 47 kDa;
Chromosome
12
Map Location
12q12
Summary
involved in the regulation of arthritis severity in rats [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Ncf1

Proteins

neutrophil cytosol factor 1
Refseq ID NP_446186
Protein GI 40254742
UniProt ID Q811Y3
mRNA ID NM_053734
Length 389
MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRKFTEIYEFHKMLKEMFPIEAGEIHTENRVIPHLPAPRWYDGQRAAESRQGTLTEYFNSLMGLPVKISRCPHLLNFFKVRPDDLKLPNDSQVKKPETYLTAKDGKNNVADITGPIILQTYRAIADYEKGSKTEMTVATGDVVDVVEKSESGWWFCQMKTKRGWVPASYLEPLDSPDEAEDPDPNYAGEPYVTIKAYAAVEEDEVSLSEGEAIEVIHKLLDGWWVVRKGDITGYFPSMYLQKAGEEITQAQRQIRSRGAPPRRSTIRNAQSIHQRSRKRLSQDTYRRNSVRFLQQRRRPARPGPQSPDSKDNPSTPRAKPQPAVPPRPSSDLILHRCTESTKRKLTSAV

Gene Information

Entrez Gene ID
114553
Gene Name
neutrophil cytosolic factor 1
Gene Symbol
Ncf1
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IDA:RGD C Golgi apparatus
GO:0043020 IDA:RGD C NADPH oxidase complex
GO:0005829 IDA:RGD C cytosol
GO:0030425 IDA:RGD C dendrite
GO:0016020 IDA:RGD C membrane
GO:0043025 IDA:RGD C neuronal cell body
GO:0005886 IDA:RGD C plasma membrane
GO:0005791 IDA:RGD C rough endoplasmic reticulum
GO:0035091 IEA:InterPro F phosphatidylinositol binding
GO:0016175 IEA:InterPro F superoxide-generating NADPH oxidase activity
GO:0006915 IMP:RGD P apoptotic process
GO:0055114 IDA:GOC P oxidation-reduction process
GO:0045730 IMP:RGD P respiratory burst

KEGG Pathway Links

KEGG Pathway ID Description
ko04062 Chemokine signaling pathway
rno04062 Chemokine signaling pathway
ko04666 Fc gamma R-mediated phagocytosis
rno04666 Fc gamma R-mediated phagocytosis
ko05140 Leishmaniasis
rno05140 Leishmaniasis
ko04670 Leukocyte transendothelial migration
rno04670 Leukocyte transendothelial migration
ko04380 Osteoclast differentiation
rno04380 Osteoclast differentiation
ko04145 Phagosome
rno04145 Phagosome

Domain Information

InterPro Annotations

Accession Description
IPR015039 NADPH oxidase subunit p47Phox, C-terminal
IPR001655 Neutrophil cytosol factor 1
IPR001683 Phox homologous domain
IPR001452 SH3_domain

UniProt Annotations

Entry Information

Gene Name
neutrophil cytosolic factor 1
Protein Entry
Q811Y3_RAT
UniProt ID
Q811Y3
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP012862 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
40254742 RefSeq NP_446186 389 neutrophil cytosol factor 1

Identical Sequences to LMP012862 proteins

Reference Database Accession Length Protein Name
GI:40254742 GenBank AAO32681.1 389 neutrophil cytosolic factor 1 [Rattus norvegicus]
GI:40254742 GenBank AAH61810.1 389 Neutrophil cytosolic factor 1 [Rattus norvegicus]
GI:40254742 GenBank ABY00524.1 389 Sequence 4 from patent US 7294652
GI:40254742 GenBank AEF77504.1 389 Sequence 4 from patent US 7943338

Related Sequences to LMP012862 proteins

Reference Database Accession Length Protein Name
GI:40254742 GenBank AAO32681.1 389 neutrophil cytosolic factor 1 [Rattus norvegicus]
GI:40254742 GenBank ABY00524.1 389 Sequence 4 from patent US 7294652
GI:40254742 GenBank AEF77504.1 389 Sequence 4 from patent US 7943338