Gene/Proteome Database (LMPD)

LMPD ID
LMP012912
Gene ID
140940
Species
Rattus norvegicus (Rat)
Gene Name
ADP-ribosylation factor 3
Gene Symbol
Arf3
Synonyms
Ac1-253;
Alternate Names
ADP-ribosylation factor 3; liver regeneration-related protein LRRG202;
Chromosome
7
Map Location
chromosome:7
Summary
may play a role in intracellular vesicular transport [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Arf3

Proteins

ADP-ribosylation factor 3
Refseq ID NP_543180
Protein GI 18266716
UniProt ID P61206
mRNA ID NM_080904
Length 181
MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK

Gene Information

Entrez Gene ID
140940
Gene Name
ADP-ribosylation factor 3
Gene Symbol
Arf3
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:UniProtKB-KW C Golgi apparatus
GO:0005525 IEA:UniProtKB-KW F GTP binding
GO:0015031 IEA:UniProtKB-KW P protein transport
GO:0007264 IEA:InterPro P small GTPase mediated signal transduction
GO:0016192 IEA:UniProtKB-KW P vesicle-mediated transport

KEGG Pathway Links

KEGG Pathway ID Description
ko04144 Endocytosis
rno04144 Endocytosis

REACTOME Pathway Links

REACTOME Pathway ID Description
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins
5954478 PI Metabolism
5953474 Phospholipid metabolism
5954502 Synthesis of PIPs at the Golgi membrane

Domain Information

InterPro Annotations

Accession Description
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR005225 Small GTP-binding protein domain
IPR024156 Small GTPase superfamily, ARF type
IPR006689 Small GTPase superfamily, ARF/SAR type

UniProt Annotations

Entry Information

Gene Name
ADP-ribosylation factor 3
Protein Entry
ARF3_RAT
UniProt ID
P61206
Species
Rat

Comments

Comment Type Description
Function GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Similarity Belongs to the small GTPase superfamily. Arf family
Subcellular Location Golgi apparatus . Cytoplasm, perinuclear region .
Subunit Interacts with PRKCABP. Interacts with PI4KB and NCS1/FREQ at the Golgi complex

Identical and Related Proteins

Unique RefSeq proteins for LMP012912 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18266716 RefSeq NP_543180 181 ADP-ribosylation factor 3

Identical Sequences to LMP012912 proteins

Reference Database Accession Length Protein Name
GI:18266716 RefSeq XP_010621890.1 181 PREDICTED: ADP-ribosylation factor 3 [Fukomys damarensis]
GI:18266716 RefSeq XP_010621891.1 181 PREDICTED: ADP-ribosylation factor 3 [Fukomys damarensis]
GI:18266716 RefSeq XP_010621892.1 181 PREDICTED: ADP-ribosylation factor 3 [Fukomys damarensis]
GI:18266716 RefSeq XP_010594619.1 181 PREDICTED: ADP-ribosylation factor 3 isoform X2 [Loxodonta africana]

Related Sequences to LMP012912 proteins

Reference Database Accession Length Protein Name
GI:18266716 GenBank EGW10399.1 181 ADP-ribosylation factor 3 [Cricetulus griseus]
GI:18266716 RefSeq XP_004558836.1 181 PREDICTED: ADP-ribosylation factor 3-like isoform X1 [Maylandia zebra]
GI:18266716 RefSeq XP_004558837.1 181 PREDICTED: ADP-ribosylation factor 3-like isoform X2 [Maylandia zebra]