Gene/Proteome Database (LMPD)
LMPD ID
LMP012919
Gene ID
Species
Rattus norvegicus (Rat)
Gene Name
acyl-CoA thioesterase 8
Gene Symbol
Synonyms
Pte1;
Alternate Names
acyl-coenzyme A thioesterase 8; PTE-1; PTE-2; choloyl-coenzyme A thioesterase; peroxisomal acyl-CoA thioesterase 1; peroxisomal acyl-CoA thioesterase 2; 48-dimethylnonanoyl-CoA thioesterase; 4,8-dimethylnonanoyl-CoA thioesterase; peroxisomal long-chain acyl-CoA thioesterase 1; peroxisomal acyl-coenzyme A thioester hydrolase 1;
Chromosome
3
Map Location
3q42
Summary
thioesterase; involved in conversion of dimethylnonanoyl-CoA and dimethylheptanoyl-CoA into 4,8-dimethylnonanoic acid plus CoASH [RGD, Feb 2006]
Orthologs
Proteins
| acyl-coenzyme A thioesterase 8 | |
|---|---|
| Refseq ID | NP_570112 |
| Protein GI | 347921998 |
| UniProt ID | Q6AZ44 |
| mRNA ID | NM_130756 |
| Length | 374 |
| MATPTQKLTSTTTNQNLRLAHGNPRDFRPLERPAGSAGCLYKFPRFSHLQQAVKMSKPEDLGDANGDADRGDLSGDLRSVLVTSVLNLEPLDEDLYRGRHYWVPTSQRLFGGQIVGQALVAAAKSVSEDVHVHSLHCYFVRAGDPKVPVLYHVERTRTGASFSVRAVKAVQHGKAIFICQASFQQMQPSPLQHQFSMPTVPPPEELLDHEALIDQYLRDPNLHEKYRVGLNRIAAREVPIEIKLVNPPALNQLQTLEPKQMFWVRARGYIGDGDIKMHCCVAAYISDYAFLGTALLPHQSKYKVNFMVSLDHSMWFHAPFRADHWMLYECESPWAGGSRGLVHGRLWRRDGVLAVTCAQEGVIRSKPRVSESKL | |
Gene Information
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005739 | IEA:Ensembl | C | mitochondrion |
| GO:0005782 | IEA:Ensembl | C | peroxisomal matrix |
| GO:0052815 | IEA:Ensembl | F | medium-chain acyl-CoA hydrolase activity |
| GO:0016290 | IEA:Ensembl | F | palmitoyl-CoA hydrolase activity |
| GO:0006637 | IEA:Ensembl | P | acyl-CoA metabolic process |
| GO:0043649 | IEA:Ensembl | P | dicarboxylic acid catabolic process |
| GO:0016559 | IEA:Ensembl | P | peroxisome fission |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| rno01100 | Metabolic pathways |
| ko04146 | Peroxisome |
| rno04146 | Peroxisome |
| ko00120 | Primary bile acid biosynthesis |
| rno00120 | Primary bile acid biosynthesis |
REACTOME Pathway Links
| REACTOME Pathway ID | Description |
|---|---|
| 5954181 | Beta-oxidation of pristanoyl-CoA |
| 5954188 | Beta-oxidation of very long chain fatty acids |
| 5953720 | Bile acid and bile salt metabolism |
| 5953250 | Metabolism |
| 5953289 | Metabolism of lipids and lipoproteins |
| 5953470 | Peroxisomal lipid metabolism |
| 5953930 | Synthesis of bile acids and bile salts |
| 5953931 | Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 5954542 | alpha-linolenic (omega3) and linoleic (omega6) acid metabolism |
| 5954543 | alpha-linolenic acid (ALA) metabolism |
Domain Information
UniProt Annotations
Entry Information
Identical and Related Proteins
Unique RefSeq proteins for LMP012919 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 347921998 | RefSeq | NP_570112 | 374 | acyl-coenzyme A thioesterase 8 |
Identical Sequences to LMP012919 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|
Related Sequences to LMP012919 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:347921998 | GenBank | AAH78751.1 | 320 | Acyl-CoA thioesterase 8 [Rattus norvegicus] |
| GI:347921998 | GenBank | EDL96493.1 | 320 | acyl-CoA thioesterase 8, isoform CRA_a [Rattus norvegicus] |
| GI:347921998 | SwissProt | Q8VHK0.1 | 320 | RecName: Full=Acyl-coenzyme A thioesterase 8; Short=Acyl-CoA thioesterase 8; AltName: Full=Choloyl-coenzyme A thioesterase; AltName: Full=Peroxisomal acyl-CoA thioesterase 2; Short=PTE-2; AltName: Full=Peroxisomal acyl-coenzyme A thioester hydrolase 1; Short=PTE-1; AltName: Full=Peroxisomal long-chain acyl-CoA thioesterase 1 [Rattus norvegicus] |