Gene/Proteome Database (LMPD)

LMPD ID
LMP012953
Gene ID
192154
Species
Rattus norvegicus (Rat)
Gene Name
huntingtin interacting protein 1
Gene Symbol
Hip1
Alternate Names
huntingtin-interacting protein 1;
Chromosome
12
Map Location
12q12
Summary
human homolog binds clathrin and the clathrin adaptor AP2; may play a role in clathrin-mediated endocytosis [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Hip1

Proteins

huntingtin-interacting protein 1
Refseq ID NP_001093945
Protein GI 215272398
UniProt ID G3V8Y8
mRNA ID NM_001100475
Length 1030
MDRMASSMKQVPNPLPKVLSRRGVGAGMEAAERESFERTQTVSVNKAINTQEVAVKEKHARTCILGTHHEKGAQTFWSVVNRLPLSSNAMLCWKFCHVFHKLLRDGHPNVLKDSLRYKNELSDMSRMWGHLSEGYGQLCSIYLKLLRTRMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTTAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCLPADTLQGHRDRFMEQFTKLKDLFQRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPVVVIPAEVSSPDSEPVLEKDDLMDMDASQQSLFDNKFDDIFGSSLSSDPFNFNNQNGVNKDEKDHLIERLYREISGLTGQLDNVKIESQRAMLQLKGRVSELEAELAEQQHLGRQATDDCEFLRTELDELKRQREDTEKAQRSLTEIEKKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSVARQAQVDLEREKKELADSFARTQEQQDVLETLKHELATSRQELQVLHGNLETSAQSEAKWLTQIAELEKEQGSLATAAAQREEEFSALRDQLESTQLKLAGAQDSMCQQIKDQRRILLAGARKAAELEIQEALGQLEEPALLISCAGATDHLLSKVNSVSSCLEQLEKSRSQYLACPEEISELLHSITLLGHLTSDTIIQGTATSLRAPPESADSLTEACRQYGRETLAYLSSLEEEGAMEKADTTAIANCLGKIKTIGEELLPRGLDIKQEELGDLVDKEMAATSAAIEAATTRIEEILSKSRAGDTGVKLEVNERILGSCTSLMQAIKVLVVASKDLQKEIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATIMVDAADLVVQGKGKFEELMVCSHEIAASTAQLVAASKVKANKGSLNLTQLQQASRGVNQATAAVVASTISGKSQIEETDSMDFSSMTLTQIKRQEMDSQVRVLELENDLQKERQKLGELRKKHYELAGVAEGWEEGTEASPSAVQEAVPDKE

Gene Information

Entrez Gene ID
192154
Gene Name
huntingtin interacting protein 1
Gene Symbol
Hip1
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:Ensembl C Golgi apparatus
GO:0030118 TAS:RGD C clathrin coat
GO:0030136 IEA:Ensembl C clathrin-coated vesicle
GO:0016021 TAS:RGD C integral component of membrane
GO:0030276 IDA:RGD F clathrin binding
GO:0035091 IEA:Ensembl F phosphatidylinositol binding
GO:0006919 IEA:Ensembl P activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0097190 IEA:Ensembl P apoptotic signaling pathway
GO:0048268 IDA:RGD P clathrin coat assembly
GO:0006897 TAS:RGD P endocytosis
GO:0048260 IEA:Ensembl P positive regulation of receptor-mediated endocytosis

KEGG Pathway Links

KEGG Pathway ID Description
ko05016 Huntington's disease
rno05016 Huntington's disease

Domain Information

InterPro Annotations

Accession Description
IPR011417 AP180 N-terminal homology (ANTH) domain
IPR008942 ENTH_VHS
IPR013809 Epsin-like_N
IPR002558 ILWEQ_dom

UniProt Annotations

Entry Information

Gene Name
huntingtin interacting protein 1
Protein Entry
G3V8Y8_RAT
UniProt ID
G3V8Y8
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP012953 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
215272398 RefSeq NP_001093945 1030 huntingtin-interacting protein 1

Identical Sequences to LMP012953 proteins

Reference Database Accession Length Protein Name
GI:215272398 GenBank EDM13367.1 1030 huntingtin interacting protein 1, isoform CRA_a [Rattus norvegicus]

Related Sequences to LMP012953 proteins

Reference Database Accession Length Protein Name
GI:215272398 GenBank EDM13367.1 1030 huntingtin interacting protein 1, isoform CRA_a [Rattus norvegicus]
GI:215272398 RefSeq NP_666113.2 1029 huntingtin-interacting protein 1 [Mus musculus]
GI:215272398 RefSeq XP_006249160.1 1038 PREDICTED: huntingtin-interacting protein 1 isoform X1 [Rattus norvegicus]
GI:215272398 RefSeq XP_008767336.1 1038 PREDICTED: huntingtin-interacting protein 1 isoform X1 [Rattus norvegicus]