Gene/Proteome Database (LMPD)

LMPD ID
LMP012996
Gene ID
282838
Species
Rattus norvegicus (Rat)
Gene Name
GM2 ganglioside activator
Gene Symbol
Gm2a
Alternate Names
ganglioside GM2 activator; GM2 ganglioside activator protein;
Chromosome
10
Map Location
10q22
Summary
mouse homolog is involved in sphingolipid metabolism [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Gm2a

Proteins

ganglioside GM2 activator precursor
Refseq ID NP_758838
Protein GI 48976085
UniProt ID Q6IN37
mRNA ID NM_172335
Length 199
MRRVPLLLVLGLLFVLGLLFAGPVAPSRLISKRPSQLGGFSWDNCDEGKDPAVIKSLTLQPDPIVVPGDVIVSAEGKTSIPLTSPQKVELTVEKEVAGFWVKIPCVEQLGSCTYENVCDLIDQYIPPGETCPEPLHTYGLPCHCPFKEGTYSLPSSNFTVPDLELPSWLSTGNYRIQSILSSGGKRLACIKIAASLKGK
sig_peptide: 1..21 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2354 peptide sequence: MRRVPLLLVLGLLFVLGLLFA

Gene Information

Entrez Gene ID
282838
Gene Name
GM2 ganglioside activator
Gene Symbol
Gm2a
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0045179 IDA:RGD C apical cortex
GO:0005737 IDA:RGD C cytoplasm
GO:0009898 IDA:RGD C cytoplasmic side of plasma membrane
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0005764 IDA:RGD C lysosome
GO:0005739 IEA:Ensembl C mitochondrion
GO:0004563 IEA:Ensembl F beta-N-acetylhexosaminidase activity
GO:0008289 IC:RGD F lipid binding
GO:0005319 IDA:RGD F lipid transporter activity
GO:0016004 IDA:RGD F phospholipase activator activity
GO:0006689 IEA:Ensembl P ganglioside catabolic process
GO:0001573 IDA:RGD P ganglioside metabolic process
GO:0007611 IEA:Ensembl P learning or memory
GO:0019915 IEA:Ensembl P lipid storage
GO:0006869 IDA:RGD P lipid transport
GO:0050885 IEA:Ensembl P neuromuscular process controlling balance
GO:0009313 IEA:Ensembl P oligosaccharide catabolic process
GO:0051345 IDA:RGD P positive regulation of hydrolase activity

KEGG Pathway Links

KEGG Pathway ID Description
ko04142 Lysosome
rno04142 Lysosome

REACTOME Pathway Links

REACTOME Pathway ID Description
5954485 Glycosphingolipid metabolism
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins
5954267 Sphingolipid metabolism

Domain Information

InterPro Annotations

Accession Description
IPR028996 Ganglioside GM2 activator
IPR003172 MD-2-related lipid-recognition domain

UniProt Annotations

Entry Information

Gene Name
GM2 ganglioside activator
Protein Entry
Q6IN37_RAT
UniProt ID
Q6IN37
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP012996 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
48976085 RefSeq NP_758838 199 ganglioside GM2 activator precursor

Identical Sequences to LMP012996 proteins

Reference Database Accession Length Protein Name
GI:48976085 GenBank AAH72474.1 199 GM2 ganglioside activator [Rattus norvegicus]
GI:48976085 GenBank EDM04464.1 199 GM2 ganglioside activator protein [Rattus norvegicus]

Related Sequences to LMP012996 proteins

Reference Database Accession Length Protein Name
GI:48976085 DBBJ BAC24018.1 199 GM2 activator protein [Rattus norvegicus]
GI:48976085 GenBank AAB06275.1 193 GM2 activator protein [Mus musculus]
GI:48976085 GenBank AAH72474.1 199 GM2 ganglioside activator [Rattus norvegicus]
GI:48976085 GenBank EDM04464.1 199 GM2 ganglioside activator protein [Rattus norvegicus]