Gene/Proteome Database (LMPD)

LMPD ID
LMP013031
Gene ID
289021
Species
Rattus norvegicus (Rat)
Gene Name
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
Gene Symbol
Pik3c2b
Alternate Names
phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; nuclear cap binding protein subunit 2; phosphoinositide-3-kinase, class 2, beta polypeptide; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta;
Chromosome
13
Map Location
13q13

Proteins

phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
Refseq ID NP_001099421
Protein GI 157786960
UniProt ID D3ZVF3
mRNA ID NM_001105951
Length 1621
MSSTQGNGEHWKSLESVGISRKELAMAEALQMEYDALSRLRHHKEESRAKQNTEPSLISWDEPALDFYSKPAGRRTELKLLRGLSGSDPTLNYNSISPPEELPNSTSQDPQPGTDPWPKGSQSGDYLYIFDGSDGRCSLSPVSGDTDGSCKKLSPPPLPPRVSIWDAPPLPPRKGSPSPSKISQPDDINSFSLVEQPSDKLLGAQDPGEGELPNGGGQRHVLGSVDYDGINDAITRLNLKSTYDSEILSDATRGWKEGRGPLDFSKDTSGKPVARSKTMPPQVPPRTYTPRYANRKNATPGKNRRISAAPVSSRTHTVTNGHELFEVSEERDEEVAAFCHMLDILRTGSDTQDYSLTGCVWSTVTPSPEHLGDEVNLKVTVLCDSLREPLTFTCNCSSTVDLLIYQTLCYTHDELREVDVGDFVLKPCGLEEFLQNKHALGSHEYIQHCRKFDINIRLQLMEQKAIRSDLARTVNDDQSPSTLNYLIHLQERPVKQTISRQALSLLFDTYHNEVDAFLLAEGDFPLKADRVVQSVKAICNALAAVETPEITSALNQLPPCPSRMQPKIQKKVVEALTAAILDLVELYCSTFNADFQTAVPGSRKHDLVQEACHFSGALAFTVYGTHRIPIIWATSYEEFYLSCSLSHGGKELCSPLQTRRAHFSKYLFHLIIWDQQICFPVQVNRLPRETLLCATLYALPIPPPGSSSEANKQKRVPEALGWVTTPLFNFRQVLTCGRKLLGLWPATQENSSARWSAPNFHQPDSVILQIDFPTSAFDIKFTSPPGDKFSPRYEFGSLREEDQRKLKDITQKESLYWLSDADKKQLWEKRYYCHTEVSSLPLVLASAPSWEWACLPDIYALLQQWTHMNHQDALGLLHATFPDQEVRRMAVQWIGSLSDAELLDYLPQLVQALKYECYLDSPLVRFLLKRAISDLRVTHYFFWLLKDSLKDSQFSIRYQYLLAALLCCCGKGLREEFNRQCWLVNTLAKLAQQVREATPSARQGILRAGLEEVRQFFALNGSCRLPLSPSLLVKGIVPRDCSYFNSNAVPLKLAFQNVDPLGENIRVIFKCGDDLRQDMLTLQMIRIMSKIWVQEGLDMRMVIFRCFSTGRGKGMVEMIPNAETLRKIQVEHGVTGSFKDRPLADWLQKHNPGEDEYEKAVENFIYSCAGCCVATYILGICDRHNDNIMLKTTGHMFHIDFGRFLGHAQMFGNIKRDRAPFVFTSDMAYVINGGDKPSSRFHDFVDLCCQAYNLIRKHTHLFLNLLGLMLSCGIPELSDLEDLKYVYDALRPQDTEANATTYFTRLIESSLGSVATKLNFFIHNLAQMKFTGSDDRLTLSFAPRTHTLKSSGRIRDVFLCRHEKVFHPSKGYIYVVKVMRENAHEATYIQRTFEEFQELHNKLRLLFPSSFLPSFPSRFVIGRSRGEAVAERRKEELNGYIWHLIHAAPEVAECDLVYTFFHPLPRDEKTSGPSPAPKSSDGTWARPVGKVGGEVKLSISYKNNKLFIMVMHIRGLQPLQDGSDPDPYVKIYLLPDPQKATKRKTKVARKTCNPTYNEMLVYDGIPKGDLQQRELQLSVLSEQGFWENVLLGEVHIRLRELDLAQEKTGWFALGSRGHGTL

Gene Information

Entrez Gene ID
289021
Gene Name
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
Gene Symbol
Pik3c2b
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0030139 IEA:Ensembl C endocytic vesicle
GO:0005942 IBA:RefGenome C phosphatidylinositol 3-kinase complex
GO:0005886 IBA:RefGenome C plasma membrane
GO:0016303 IBA:RefGenome F 1-phosphatidylinositol-3-kinase activity
GO:0035005 IBA:RefGenome F 1-phosphatidylinositol-4-phosphate 3-kinase activity
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0001727 IEA:Ensembl F lipid kinase activity
GO:0035091 IEA:InterPro F phosphatidylinositol binding
GO:0036092 IBA:GOC P phosphatidylinositol-3-phosphate biosynthetic process
GO:0048015 IEA:InterPro P phosphatidylinositol-mediated signaling
GO:0043491 IEA:Ensembl P protein kinase B signaling

KEGG Pathway Links

KEGG Pathway ID Description
ko00562 Inositol phosphate metabolism
rno00562 Inositol phosphate metabolism
rno01100 Metabolic pathways
ko04070 Phosphatidylinositol signaling system
rno04070 Phosphatidylinositol signaling system

REACTOME Pathway Links

REACTOME Pathway ID Description
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins
5954478 PI Metabolism
5953474 Phospholipid metabolism
5954499 Synthesis of PIPs at the plasma membrane

Domain Information

InterPro Annotations

Accession Description
IPR016024 Armadillo-type fold
IPR000008 C2 domain
IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain
IPR000341 Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain
IPR002420 Phosphatidylinositol 3-kinase, C2 domain
IPR018936 Phosphatidylinositol 3/4-kinase, conserved site
IPR015433 Phosphatidylinositol Kinase
IPR001263 Phosphoinositide 3-kinase, accessory (PIK) domain
IPR001683 Phox homologous domain
IPR011009 Protein kinase-like domain
IPR029071 Ubiquitin-related domain

UniProt Annotations

Entry Information

Gene Name
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
Protein Entry
D3ZVF3_RAT
UniProt ID
D3ZVF3
Species
Rat

Comments

Comment Type Description
Similarity Contains 1 C2 domain
Similarity Contains PI3K/PI4K domain
Similarity Contains PIK helical domain

Identical and Related Proteins

Unique RefSeq proteins for LMP013031 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
157786960 RefSeq NP_001099421 1621 phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

Identical Sequences to LMP013031 proteins

Reference Database Accession Length Protein Name
GI:157786960 GenBank EDM09779.1 1621 phosphoinositide-3-kinase, class 2, beta polypeptide (predicted) [Rattus norvegicus]

Related Sequences to LMP013031 proteins

Reference Database Accession Length Protein Name
GI:157786960 GenBank EDL39659.1 1620 mCG142624 [Mus musculus]
GI:157786960 GenBank EDM09779.1 1621 phosphoinositide-3-kinase, class 2, beta polypeptide (predicted) [Rattus norvegicus]
GI:157786960 RefSeq XP_006249816.1 1633 PREDICTED: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [Rattus norvegicus]
GI:157786960 RefSeq XP_008767664.1 1633 PREDICTED: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [Rattus norvegicus]