Gene/Proteome Database (LMPD)

LMPD ID
LMP013036
Gene ID
289312
Species
Rattus norvegicus (Rat)
Gene Name
acyl-CoA binding domain containing 3
Gene Symbol
Acbd3
Alternate Names
Golgi resident protein GCP60; DAP; GOCAP1; GOLPH1; golgi phosphoprotein 1; DMT1-associated protein; golgi complex-associated protein 1; acyl-Coenzyme A binding domain containing 3; acyl-CoA-binding domain-containing protein 3; neurotrophin receptor alike death domain protein; p75-like apoptosis-inducing death domain protein;
Chromosome
13
Map Location
13q26
Summary
mouse homolog associates with peripheral-type benzodiazepine receptor and the regulatory subunit RIalpha of PKA [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Acbd3

Proteins

Golgi resident protein GCP60
Refseq ID NP_878263
Protein GI 33469059
UniProt ID Q7TNY6
mRNA ID NM_182843
Length 526
MAAQLNVEQLEVSLDGLTLSPDSEERPGAEGAPLQTPPSSPPRDGLGSGTAGQQREPGEAAAEGAAEEARRMEQHWGFGLEELYGLALRFYKIKDGKAFHPTYEEKLKFVALHKQVLLGPYNPDTSPEVGFFDVLGNDRRREWAALGNMSKEDAMVEFVKLLNKCCPLLSAYVASHRIEKEEEEKRRKAEEERRQREEEERERLQKEEEKRKREEEDRLRREEEERRRIEEERLRLEQQKQQIMAALNSQTAVQFQQYAAQQYPGNYEQQQILIRQLQEQHYQQYMQQLYQVQLAQQQAALQKQQEVVVAGASLPASTKVNTAGASDPLPVNGQAKTHTENPEKVLEPEAAEEALENGPKDSLPVIAAPSMWTRPQIKDFKEKIRQDADSVITVRRGEVVTVRVPTHEEGSYLFWEFATDSYDIGFGVYFEWTDSPNAAVSVHVSESSDDEEEEEEENVTCEEKAKKNVNKPLLDEIVPVYRRDCHEEVYAGSHQYPGRGVYLLKFDNSYSLWRSKSVYYRVYYTR

Gene Information

Entrez Gene ID
289312
Gene Name
acyl-CoA binding domain containing 3
Gene Symbol
Acbd3
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0000139 IDA:UniProtKB C Golgi membrane
GO:0016021 IEA:InterPro C integral component of membrane
GO:0005739 IEA:UniProtKB-KW C mitochondrion
GO:0000062 IEA:InterPro F fatty-acyl-CoA binding
GO:0006694 IEA:UniProtKB-KW P steroid biosynthetic process
GO:0006810 IEA:InterPro P transport

Domain Information

InterPro Annotations

Accession Description
IPR000582 Acyl-CoA-binding protein, ACBP
IPR022408 Acyl-CoA-binding protein, ACBP, conserved site
IPR014352 FERM/acyl-CoA-binding protein, 3-helical bundle
IPR009038 GOLD

UniProt Annotations

Entry Information

Gene Name
acyl-CoA binding domain containing 3
Protein Entry
GCP60_RAT
UniProt ID
Q7TNY6
Species
Rat

Comments

Comment Type Description
Domain The GOLD domain is essential for giantin binding
Function Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity)
Similarity Contains 1 ACB (acyl-CoA-binding) domain
Similarity Contains 1 GOLD domain. {ECO:0000255|PROSITE- ProRule:PRU00096}.
Subcellular Location Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side {ECO:0000250}. Mitochondrion . Note=Also mitochondrial (via its interaction with PBR)
Subunit Interacts with the C-terminal cytoplasmic domain of giantin/GOLGB1. Interacts with PBR and PKA regulatory subunit RI- alpha. Does not interact with PKA regulatory subunit RI-beta nor PKA regulatory subunit RII-alpha (By similarity)

Identical and Related Proteins

Unique RefSeq proteins for LMP013036 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
33469059 RefSeq NP_878263 526 Golgi resident protein GCP60

Identical Sequences to LMP013036 proteins

Reference Database Accession Length Protein Name
GI:33469059 GenBank AAP94639.1 526 DMT1-associated protein [Rattus norvegicus]
GI:33469059 SwissProt Q7TNY6.3 526 RecName: Full=Golgi resident protein GCP60; AltName: Full=Acyl-CoA-binding domain-containing protein 3; AltName: Full=DMT1-associated protein; Short=DAP; AltName: Full=Golgi complex-associated protein 1; Short=GOCAP1; AltName: Full=Golgi phosphoprotein 1; Short=GOLPH1 [Rattus norvegicus]

Related Sequences to LMP013036 proteins

Reference Database Accession Length Protein Name
GI:33469059 GenBank AAP94639.1 526 DMT1-associated protein [Rattus norvegicus]
GI:33469059 GenBank AAH83877.1 526 Acyl-Coenzyme A binding domain containing 3 [Rattus norvegicus]
GI:33469059 GenBank EDL94830.1 526 acyl-Coenzyme A binding domain containing 3 [Rattus norvegicus]
GI:33469059 SwissProt Q7TNY6.3 526 RecName: Full=Golgi resident protein GCP60; AltName: Full=Acyl-CoA-binding domain-containing protein 3; AltName: Full=DMT1-associated protein; Short=DAP; AltName: Full=Golgi complex-associated protein 1; Short=GOCAP1; AltName: Full=Golgi phosphoprotein 1; Short=GOLPH1 [Rattus norvegicus]