Gene/Proteome Database (LMPD)

LMPD ID
LMP013080
Gene ID
291841
Species
Rattus norvegicus (Rat)
Gene Name
CCR4-NOT transcription complex, subunit 1
Gene Symbol
Cnot1
Synonyms
RGD1308009;
Alternate Names
CCR4-NOT transcription complex subunit 1; adrenal gland protein AD-005;
Chromosome
19
Map Location
19p13

Proteins

CCR4-NOT transcription complex subunit 1
Refseq ID NP_001128312
Protein GI 198386347
UniProt ID G3V7M0
mRNA ID NM_001134840
Length 2376
MNLDSLSLALSQISYLVDNLTKKNYRASQQEIQHIVNRHGPEADRHLLRCLFSHVDFSGDGKSSGKDFHQTQFLIQECASLITKPNFISTLSYAIDNPLHYQKSLKPAPHLFAQLSKVLKLSKVQEVIFGLALLNSSSPDLRGFAAQFIKQKLPDLLRSYIDADVSGNQEGGFQDIAIEVLHLLLSHLLFGQKGAFGVGQEQIDAFLKTLRRDFPQERCPVVLAPLLYPEKRDILMDRILPDSGGVAKTMMESSLADFMQEVGYGFCASIEECRNIIMQFGVREVTAAQVARVLGMMARTHSGLTDGIPLQSISAPGSGIWSDGKDKSEGAQAHTWNVEVLIDVLKELNPSLNFKEVTYELDHPGFQIRDSKGLHNVVYGIQRGLGMEVFPVDFIYRPWKHAEGQLSFIQHSLINPEVFCFADYPCHTVATDILKAPPEDDNREIATWKSLDLIESLLRLAEVGQYEQVKQLFSFPIKHCPDMLVLALLQINTSWHTLRHELISTLMPIFLGNHPNSAIILHYAWHGQGQSPSIRQLIMHAMAEWYMRGEQYDQAKLSRILDVAQDLKALSMLLNGTPFAFVIDLAALASRREYLKLDKWLTDKIREHGEPFIQACMTFLKRRCPSILGGLAPEKDQPKSAQLPAETLATMLACLQACAGSVSQELSETILTMVANCSNVMNKARQPPPGVMPKGRPPSASSLDAISPVQIDPLAGMASLSIGGSAAPHTQSMQGFPPNLGSAFSTPQSPAKAFPPLSTPNQTTAFSGIGGLSSQLPVGGLGTGSLTGIGTGALGLPAVNSDPFVQRKLGTSGLNQPTFQQSKMKPSDLSQVWPEANQHFSKEIDDEANSYFQRIYNHPPHPTMSVDEVLEMLQRFKDSTIKREREVFNCMLRNLFEEYRFFPQYPDKELHITACLFGGIIEKGLVTYMALGLALRYVLEALRKPFGSKMYYFGIAALDRFKNRLKDYPQYCQHLASISHFMQFPHHLQEYIEYGQQSRDPPVKMQGSITTPGSIALAQAQAQAQVPAKAPLAGQVNTMVTTSTTTTVAKTVTVTKPTGVSFKKDVPPSINTTNIDTLLVATDQTERIVEPPENIQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQYLVMKRVSIEPNFHSLYSNFLDTLKNPEFNKMVLNETYRNIKVLLTSDKAAANFSDRSLLKNLGHWLGMITLAKNKPILHTDLDVKSLLLEAYVKGQQELLYVVPFVAKVLESSIRSLVFRPPNPWTMAIMNVLAELHQEHDLKLNLKFEIEVLCKNLALDINELKPGNLLKDKDRLKNLDEQLSAPKKDVKQPEELPAITTTTTSTTPATSTTCTATVPPQPQYSYHDINVYSLAGLAPHITLNPTIPLFQAHPQLKQCVRQAIERAVQELVHPVVDRSIKIAMTTCEQIVRKDFALDSEESRMRIAAHHMMRNLTAGMAMITCREPLLMSISTNLKNSFASALRTASPQQREMMDQAAAQLAQDNCELACCFIQKTAVEKAGPEMDKRLATEFELRKHARQEGRRYCDPVVLTYQAERMPEQIRLKVGGVDPKQLAVYEEFARNVPGFLPTNDLSQPTGFLAQPMKQAWATDDVAQIYDKCITELEQHLHAIPPTLAMNPQAQALRSLLEVVVLSRNSRDAIAALGLLQKAVEGLLDATSGADADLLLRYRECHLLVLKGLQDGRAYGSPWCNKQITRCLIECRDEYKYNVEAVELLIRNHLVNMQQYDLHLAQSMENGLNYMAVAFAMQLVKILLVDERSVAHITEADLFHTIETLMRINAHSRGNAPEGLPQLMEVVRSNYEAMIDRAHGGPNFMMHSGISQASEYDDPPGLREKAEYLLREWVNLYHSAAAGRDSTKAFSAFVGQMHQQGILKTDDLITRFFRLCTEMCVEISYRAQAEQQHNPAANPTMIRAKCYHNLDAFVRLIALLVKHSGEATNTVTKINLLNKVLGIVVGVLLQDHDVRQSEFQQLPYHRIFIMLLLELNAPEHVLETINFQTLTAFCNTFHILRPTKAPGFVYAWLELISHRIFIARMLAHTPQQKGWPMYAQLLIDLFKYLAPFLRNVELTKPMQILYKGTLRVLLVLLHDFPEFLCDYHYGFCDVIPPNCIQLRNLILSAFPRNMRLPDPFTPNLKVDMLSEINIAPRILTNFTGVMPPQFKKDLDSYLKTRSPVTFLSDLRSNLQVSNEPGNRYNLQLINALVLYVGTQAIAHIHNKGSTPSMSTITHSAHMDIFQNLAVDLDTEGRYLFLNAIANQLRYPNSHTHYFSCTMLYLFAEANTEAIQEQITRVLLERLIVNRPHPWGLLITFIELIKNPAFKFWNHEFVHCAPEIEKLFQSVAQCCMGQKQAQQVMEGTGAS

Gene Information

Entrez Gene ID
291841
Gene Name
CCR4-NOT transcription complex, subunit 1
Gene Symbol
Cnot1
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0030014 IEA:Ensembl C CCR4-NOT complex
GO:0000932 IEA:Ensembl C cytoplasmic mRNA processing body
GO:0005615 IEA:Ensembl C extracellular space
GO:0005634 IEA:Ensembl C nucleus
GO:0005778 IEA:Ensembl C peroxisomal membrane
GO:0044822 IEA:Ensembl F poly(A) RNA binding
GO:0004535 IEA:Ensembl F poly(A)-specific ribonuclease activity
GO:0033147 IEA:Ensembl P negative regulation of intracellular estrogen receptor signaling pathway
GO:0048387 IEA:Ensembl P negative regulation of retinoic acid receptor signaling pathway
GO:0000122 IEA:Ensembl P negative regulation of transcription from RNA polymerase II promoter
GO:0010606 IEA:Ensembl P positive regulation of cytoplasmic mRNA processing body assembly
GO:1900153 IEA:Ensembl P positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0060213 IEA:Ensembl P positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:2000036 IEA:Ensembl P regulation of stem cell maintenance
GO:0001829 IEA:Ensembl P trophectodermal cell differentiation

KEGG Pathway Links

KEGG Pathway ID Description
ko03018 RNA degradation
rno03018 RNA degradation

REACTOME Pathway Links

REACTOME Pathway ID Description
5954276 Deadenylation of mRNA
5954274 Deadenylation-dependent mRNA decay
5953330 Gene Expression

Domain Information

InterPro Annotations

Accession Description
IPR007196 CCR4-Not complex component, Not1, C-terminal
IPR024557 CCR4-Not complex, Not1 subunit, domain of unknown function DUF3819

UniProt Annotations

Entry Information

Gene Name
CCR4-NOT transcription complex, subunit 1
Protein Entry
G3V7M0_RAT
UniProt ID
G3V7M0
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP013080 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
198386347 RefSeq NP_001128312 2376 CCR4-NOT transcription complex subunit 1

Identical Sequences to LMP013080 proteins

Reference Database Accession Length Protein Name
GI:198386347 GenBank EDL87270.1 2376 rCG39079 [Rattus norvegicus]

Related Sequences to LMP013080 proteins

Reference Database Accession Length Protein Name
GI:198386347 GenBank EDL11182.1 2376 mCG133345, isoform CRA_a [Mus musculus]
GI:198386347 GenBank EDL87270.1 2376 rCG39079 [Rattus norvegicus]
GI:198386347 RefSeq XP_006530937.1 2376 PREDICTED: CCR4-NOT transcription complex subunit 1 isoform X5 [Mus musculus]
GI:198386347 RefSeq XP_008770493.1 2375 PREDICTED: CCR4-NOT transcription complex subunit 1 isoform X1 [Rattus norvegicus]