Gene/Proteome Database (LMPD)

LMPD ID
LMP013099
Gene ID
293173
Species
Rattus norvegicus (Rat)
Gene Name
fatty acyl CoA reductase 1
Gene Symbol
Far1
Synonyms
Mlstd2;
Alternate Names
fatty acyl-CoA reductase 1; male sterility domain containing 2; male sterility domain-containing protein 2;
Chromosome
1
Map Location
1q34
EC Number
1.2.1.n2

Proteins

fatty acyl-CoA reductase 1
Refseq ID NP_001011933
Protein GI 58865436
UniProt ID Q66H50
mRNA ID NM_001011933
Length 515
MVSIPEYYEGKNILLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEILSGKLFDRLRDENPDFRQKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQLNVIATRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLEWMDDGLVNDITPKLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGILRTMRASNNALADLVPVDVVVNTSLAAAWYSGVNRPRNIMVYNCTTGSTNPFHWGEVGDYLNHSFKTNPLNQVFRHPYVKFYSNNLMLHYWKGVKHTVPALLLDLALRLTGQKPWMMKTITRLHKAMVFLEYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCMGTKKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILVILIWRIFIARSQMARNIWYFVVSLCYKFLSYFRASSTMRY

Gene Information

Entrez Gene ID
293173
Gene Name
fatty acyl CoA reductase 1
Gene Symbol
Far1
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005778 IEA:Ensembl C peroxisomal membrane
GO:0080019 IEA:InterPro F fatty-acyl-CoA reductase (alcohol-forming) activity
GO:0050062 IEA:Ensembl F long-chain-fatty-acyl-CoA reductase activity
GO:0008611 IEA:Ensembl P ether lipid biosynthetic process
GO:0046474 IEA:Ensembl P glycerophospholipid biosynthetic process
GO:0035336 IEA:Ensembl P long-chain fatty-acyl-CoA metabolic process
GO:0010025 IEA:Ensembl P wax biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ko04146 Peroxisome
rno04146 Peroxisome

REACTOME Pathway Links

REACTOME Pathway ID Description
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins
5953470 Peroxisomal lipid metabolism
5953469 Plasmalogen biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR026055 Fatty acyl-CoA reductase
IPR013120 Male sterility, NAD-binding
IPR016040 NAD(P)-binding domain

UniProt Annotations

Entry Information

Gene Name
fatty acyl CoA reductase 1
Protein Entry
FACR1_RAT
UniProt ID
Q66H50
Species
Rat

Comments

Comment Type Description
Catalytic Activity Hexadecanal + CoA + NADP(+) = hexadecanoyl-CoA + NADPH.
Function Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols
Similarity Belongs to the fatty acyl-CoA reductase family
Subcellular Location Peroxisome membrane ; Single- pass membrane protein .
Subunit Interacts (via C-terminus) with PEX19, the interaction is required for targeting to peroxisomes

Identical and Related Proteins

Unique RefSeq proteins for LMP013099 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
58865436 RefSeq NP_001011933 515 fatty acyl-CoA reductase 1

Identical Sequences to LMP013099 proteins

Reference Database Accession Length Protein Name
GI:58865436 GenBank AAH82015.1 515 Fatty acyl CoA reductase 1 [Rattus norvegicus]
GI:58865436 GenBank EDM17791.1 515 rCG39451, isoform CRA_a [Rattus norvegicus]
GI:58865436 RefSeq XP_006230082.1 515 PREDICTED: fatty acyl-CoA reductase 1 isoform X1 [Rattus norvegicus]
GI:58865436 SwissProt Q66H50.1 515 RecName: Full=Fatty acyl-CoA reductase 1; AltName: Full=Male sterility domain-containing protein 2 [Rattus norvegicus]

Related Sequences to LMP013099 proteins

Reference Database Accession Length Protein Name
GI:58865436 GenBank AAH82015.1 515 Fatty acyl CoA reductase 1 [Rattus norvegicus]
GI:58865436 GenBank EDM17791.1 515 rCG39451, isoform CRA_a [Rattus norvegicus]
GI:58865436 RefSeq XP_006230082.1 515 PREDICTED: fatty acyl-CoA reductase 1 isoform X1 [Rattus norvegicus]
GI:58865436 SwissProt Q66H50.1 515 RecName: Full=Fatty acyl-CoA reductase 1; AltName: Full=Male sterility domain-containing protein 2 [Rattus norvegicus]