Gene/Proteome Database (LMPD)

LMPD ID
LMP013106
Gene ID
293649
Species
Rattus norvegicus (Rat)
Gene Name
low density lipoprotein receptor-related protein 5
Gene Symbol
Lrp5
Alternate Names
low-density lipoprotein receptor-related protein 5;
Chromosome
1
Map Location
1q42

Proteins

low-density lipoprotein receptor-related protein 5 precursor
Refseq ID NP_001099791
Protein GI 188536057
UniProt ID B2RYI1
mRNA ID NM_001106321
Length 1600
METAPTRAPPPPPQPLLLLLALCCSLVPAAASPLLLFANRRDVRLVDAGGVKLESTIVASGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTGAAAQNIVISGLVSPDGLACDWVGKKLYWTDSETNRIEVANLNGTSRKVLFWQDLDQPRAIALDPAHGYMYWTDWGEAPRIERAGMDGSTRKIIVDSDIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALTLSGDTLYWTDWQTRSIHACNKWTGEKRKEILSALYSPMDIQVLSQERQPPFHTPCEEGNGGCSHLCLLSPREPFYSCACPTGVQLQDNGKTCKAGAEEVLLLARRTDLRRISLDTPDFTDIVLQVGDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIVLHPVMGLMYWTDWGENPKIECANLDGRDRHVLVNTSLGWPNGLALDLQEGKLYWGDAKTDKIEVINIDGTKRQTLLEDKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKASRDVIIDQLPDLMGLKAVNVAKVVGTNPCADGNGGCSHLCFFTPHATKCGCPIGLELLSDMKTCIIPEAFLVFTSRATIHRISLETNNNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVIEFGLDYPEGMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWGGKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDLDTNMIESSNMLGQERMVIADDLPYPFGLTQYSDYIYWTDWNLHSIERADKTSGRNRTLIQGHLDFVMDILVFHSSRQDGLNDCVHSNGQCGQLCLAIPGGHRCGCASHYTLDPSSRNCSPPSTFLLFSQKFAISRMIPDDQLSPDLILPLHGLRNVKAINYDPLDKFIYWVDGRQNIKRAKDDGTQPSMLTSPSQSLSPDRQPHDLSIDIYSRTLFWTCEATNTINVHRLDGDAMGVVLRGDRDRPRAIAVNAERGYMYFTNMQDHAAKIERASLDGTEREVLFTTGLIRPVALVVDNALGKLFWVDADLKRIESCDLSGANRLTLEDANIVQPVGLTVLGRHLYWIDRQQQMIERVEKTTGDKRTRVQGRVTHLTGIHAVEEVSLEEFSAHPCARDNGGCSHICIAKGDGTPRCSCPVHLVLLQNLLTCGEPPTCSPDQFACATGEIDCIPGAWRCDGFPECADQSDEEGCPVCSASQFPCARGQCVDLRLRCDAVCLPNQFRCASGQCVLIKQQCDSFPDCADGSDELMCEINKPPSDDVPAHSSAIGPVIGIILSLFVMGGVYFVCQRVMCQRYTGASGPFPHEYVGGTPHVPLNFIAPGGSQHGPFPGIPCSKSMMSSVSLVGGRGSVPLYDRNHVTGASSSSSSSTKATLYPPILNPPPSPATDPSLYNMDMFYSSNIPSTARPYRPYIIRGMAPPTTPCSTDVCDSDYSTSRWKTSKYYLDLNSDSDPYPPPPTPHSQYLSAEDSCPPSPVTERSYCHLFPPPPSPCTDSS
sig_peptide: 1..31 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 3153 peptide sequence: METAPTRAPPPPPQPLLLLLALCCSLVPAAA

Gene Information

Entrez Gene ID
293649
Gene Name
low density lipoprotein receptor-related protein 5
Gene Symbol
Lrp5
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005886 IBA:RefGenome C plasma membrane
GO:0043235 IBA:RefGenome C receptor complex
GO:0042813 IBA:RefGenome F Wnt-activated receptor activity
GO:0017147 IBA:RefGenome F Wnt-protein binding
GO:0015026 IBA:RefGenome F coreceptor activity
GO:0044332 IBA:RefGenome P Wnt signaling pathway involved in dorsal/ventral axis specification
GO:0060612 IBA:RefGenome P adipose tissue development
GO:0009952 IBA:RefGenome P anterior/posterior pattern specification
GO:0048539 IBA:RefGenome P bone marrow development
GO:0060349 IBA:RefGenome P bone morphogenesis
GO:0046849 IBA:RefGenome P bone remodeling
GO:0060444 IBA:RefGenome P branching involved in mammary gland duct morphogenesis
GO:0060070 IBA:RefGenome P canonical Wnt signaling pathway
GO:0042632 IBA:RefGenome P cholesterol homeostasis
GO:0048596 IBA:RefGenome P embryonic camera-type eye morphogenesis
GO:0030326 IBA:RefGenome P embryonic limb morphogenesis
GO:0060059 IBA:RefGenome P embryonic retina morphogenesis in camera-type eye
GO:0001702 IBA:RefGenome P gastrulation with mouth forming second
GO:0002076 IBA:RefGenome P osteoblast development
GO:0045944 IBA:RefGenome P positive regulation of transcription from RNA polymerase II promoter
GO:0045598 IBA:RefGenome P regulation of fat cell differentiation
GO:0061178 IBA:RefGenome P regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0030278 IBA:RefGenome P regulation of ossification
GO:0043434 IEP:RGD P response to peptide hormone
GO:0061304 IBA:RefGenome P retinal blood vessel morphogenesis

KEGG Pathway Links

KEGG Pathway ID Description
ko04310 Wnt signaling pathway
rno04310 Wnt signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR000742 Epidermal growth factor-like domain
IPR000033 LDLR class B repeat
IPR017049 Low density lipoprotein receptor-related protein, 5/6
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
IPR011042 Six-bladed beta-propeller, TolB-like

UniProt Annotations

Entry Information

Gene Name
low density lipoprotein receptor-related protein 5
Protein Entry
B2RYI1_RAT
UniProt ID
B2RYI1
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP013106 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
188536057 RefSeq NP_001099791 1600 low-density lipoprotein receptor-related protein 5 precursor

Identical Sequences to LMP013106 proteins

Reference Database Accession Length Protein Name
GI:188536057 GenBank AAI66786.1 1600 Lrp5 protein [Rattus norvegicus]

Related Sequences to LMP013106 proteins

Reference Database Accession Length Protein Name
GI:188536057 GenBank AAI66786.1 1600 Lrp5 protein [Rattus norvegicus]
GI:188536057 RefSeq NP_032539.2 1614 low-density lipoprotein receptor-related protein 5 precursor [Mus musculus]
GI:188536057 RefSeq XP_006230788.1 1615 PREDICTED: low-density lipoprotein receptor-related protein 5 isoform X1 [Rattus norvegicus]
GI:188536057 SwissProt Q91VN0.3 1614 RecName: Full=Low-density lipoprotein receptor-related protein 5; Short=LRP-5; AltName: Full=Low-density lipoprotein receptor-related protein 7; Short=LRP-7; AltName: Full=Lr3; Flags: Precursor [Mus musculus]