Gene/Proteome Database (LMPD)

LMPD ID
LMP013109
Gene ID
293688
Species
Rattus norvegicus (Rat)
Gene Name
transmembrane 7 superfamily member 2
Gene Symbol
Tm7sf2
Alternate Names
delta(14)-sterol reductase;
Chromosome
1
Map Location
1q43

Proteins

delta(14)-sterol reductase
Refseq ID NP_001013089
Protein GI 61556857
UniProt ID Q5BK21
mRNA ID NM_001013071
Length 418
MASREASQAPLEFGGPLGVTAMLILLPATMFHLLLAARSGPARLLALPAYLPGLEELWSPRALLLLFIWLGLQVALYLLPARKVAEGLELKDKSRLRYPINGFQALVLTALLVGLGVSVGLPLGALPGMLLPLAFATTLTSFIFSLLLYAKALVAPASALAPGGNSGNSVYDFFLGRELNPRLGSFDFKYFCELRPGLIGWVFINLALLMQEAELRGSPSLAMWLVNGFQLLYVGDALWYEESVLTTMDIIHDGFGFMLVFGDLAWVPFTYSLQAQFLLYHPQPLGLPMALLICLIKAVGYYIFRGANSQKNTFRKNPSDPSVAGLETIPTATGRQLLVSGWWGMVRHPNYLGDLIMALAWSLPCGLSHLLPYFYLLYFTALLVHREARDEQQCLRKYGRAWQEYCKRVPYRIIPYVY

Gene Information

Entrez Gene ID
293688
Gene Name
transmembrane 7 superfamily member 2
Gene Symbol
Tm7sf2
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0043235 IEA:Ensembl C receptor complex
GO:0016628 IEA:InterPro F oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

KEGG Pathway Links

KEGG Pathway ID Description
M00101 Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol
rno01100 Metabolic pathways
ko00100 Steroid biosynthesis
rno00100 Steroid biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
5954496 Activation of gene expression by SREBF (SREBP)
5953924 Cholesterol biosynthesis
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins
5954497 Regulation of cholesterol biosynthesis by SREBP (SREBF)

Domain Information

InterPro Annotations

Accession Description
IPR001171 Ergosterol biosynthesis ERG4/ERG24
IPR018083 Sterol reductase, conserved site

UniProt Annotations

Entry Information

Gene Name
transmembrane 7 superfamily member 2
Protein Entry
Q5BK21_RAT
UniProt ID
Q5BK21
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP013109 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
61556857 RefSeq NP_001013089 418 delta(14)-sterol reductase

Identical Sequences to LMP013109 proteins

Reference Database Accession Length Protein Name
GI:61556857 GenBank AAH91237.1 418 Transmembrane 7 superfamily member 2 [Rattus norvegicus]
GI:61556857 GenBank EDM12557.1 418 transmembrane 7 superfamily member 2 [Rattus norvegicus]

Related Sequences to LMP013109 proteins

Reference Database Accession Length Protein Name
GI:61556857 DBBJ BAE33285.1 418 unnamed protein product [Mus musculus]
GI:61556857 GenBank AAQ05836.1 418 C-14 sterol reductase [Mus musculus]
GI:61556857 GenBank AAH91237.1 418 Transmembrane 7 superfamily member 2 [Rattus norvegicus]
GI:61556857 GenBank EDM12557.1 418 transmembrane 7 superfamily member 2 [Rattus norvegicus]