Gene/Proteome Database (LMPD)

LMPD ID
LMP013122
Gene ID
294422
Species
Rattus norvegicus (Rat)
Gene Name
sphingomyelin phosphodiesterase, acid-like 3A
Gene Symbol
Smpdl3a
Alternate Names
acid sphingomyelinase-like phosphodiesterase 3a; ASM-like phosphodiesterase 3a;
Chromosome
20
Map Location
20q11
EC Number
3.1.4.-

Proteins

acid sphingomyelinase-like phosphodiesterase 3a precursor
Refseq ID NP_001005539
Protein GI 53850608
UniProt ID Q641Z7
mRNA ID NM_001005539
Length 445
MALPGNFLCCLLVAWLCDPGLGVPLAPAYGAPAVGQFWHVTDLHLDPTYHITDDHTKVCASSKGANVSNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVRELSTGSVIEVITNMTVTVQNLFPNLQVFPALGNHDYWPQDQLPIATSKVYSAVSDLWKPWLDEEAISTLRKGGFYSQKVASNPDLRIISLNTNLYYGPNIMTLNKTDPANQFEWLENTLNSSLRNKEKVYVIAHVPVGYLPYATKTPAMRQYYNEKLVDIFRRYSSVIAGQFYGHTHRDSLMVLSDKNGNPINSVFVAPAVTPVKGVLEKETNNPGVRLFQYKPGDYTLLDMLQYYLNLTEANLKGESNWTLEYTLTQAYGVADLQPKSLHGLAQQLATIDSKQFLKYYHYFFVSYDSSAPCDQRCKTLQICAIMNLDLVSYEDCLKRHL
sig_peptide: 1..22 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2307 peptide sequence: MALPGNFLCCLLVAWLCDPGLG mat_peptide: 23..445 product: Acid sphingomyelinase-like phosphodiesterase 3a experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q641Z7.1) calculated_mol_wt: 47607 peptide sequence: VPLAPAYGAPAVGQFWHVTDLHLDPTYHITDDHTKVCASSKGANVSNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVRELSTGSVIEVITNMTVTVQNLFPNLQVFPALGNHDYWPQDQLPIATSKVYSAVSDLWKPWLDEEAISTLRKGGFYSQKVASNPDLRIISLNTNLYYGPNIMTLNKTDPANQFEWLENTLNSSLRNKEKVYVIAHVPVGYLPYATKTPAMRQYYNEKLVDIFRRYSSVIAGQFYGHTHRDSLMVLSDKNGNPINSVFVAPAVTPVKGVLEKETNNPGVRLFQYKPGDYTLLDMLQYYLNLTEANLKGESNWTLEYTLTQAYGVADLQPKSLHGLAQQLATIDSKQFLKYYHYFFVSYDSSAPCDQRCKTLQICAIMNLDLVSYEDCLKRHL

Gene Information

Entrez Gene ID
294422
Gene Name
sphingomyelin phosphodiesterase, acid-like 3A
Gene Symbol
Smpdl3a
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005615 IEA:InterPro C extracellular space
GO:0016798 IEA:UniProtKB-KW F hydrolase activity, acting on glycosyl bonds
GO:0004767 IEA:InterPro F sphingomyelin phosphodiesterase activity
GO:0006685 IEA:InterPro P sphingomyelin catabolic process

Domain Information

InterPro Annotations

Accession Description
IPR017064 Acid sphingomyelinase-like phosphodiesterase, predicted
IPR004843 Calcineurin-like phosphoesterase domain, apaH type
IPR029052 Metallo-dependent phosphatase-like

UniProt Annotations

Entry Information

Gene Name
sphingomyelin phosphodiesterase, acid-like 3A
Protein Entry
ASM3A_RAT
UniProt ID
Q641Z7
Species
Rat

Comments

Comment Type Description
Similarity Belongs to the acid sphingomyelinase family
Subcellular Location Secreted .

Identical and Related Proteins

Unique RefSeq proteins for LMP013122 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
53850608 RefSeq NP_001005539 445 acid sphingomyelinase-like phosphodiesterase 3a precursor

Identical Sequences to LMP013122 proteins

Reference Database Accession Length Protein Name
GI:53850608 GenBank AAH82029.1 445 Sphingomyelin phosphodiesterase, acid-like 3A [Rattus norvegicus]
GI:53850608 GenBank EDL92885.1 445 sphingomyelin phosphodiesterase, acid-like 3A, isoform CRA_a [Rattus norvegicus]
GI:53850608 SwissProt Q641Z7.1 445 RecName: Full=Acid sphingomyelinase-like phosphodiesterase 3a; Short=ASM-like phosphodiesterase 3a; Flags: Precursor [Rattus norvegicus]

Related Sequences to LMP013122 proteins

Reference Database Accession Length Protein Name
GI:53850608 GenBank AAH82029.1 445 Sphingomyelin phosphodiesterase, acid-like 3A [Rattus norvegicus]
GI:53850608 GenBank EDL92885.1 445 sphingomyelin phosphodiesterase, acid-like 3A, isoform CRA_a [Rattus norvegicus]
GI:53850608 RefSeq XP_005363700.1 450 PREDICTED: acid sphingomyelinase-like phosphodiesterase 3a [Microtus ochrogaster]
GI:53850608 SwissProt Q641Z7.1 445 RecName: Full=Acid sphingomyelinase-like phosphodiesterase 3a; Short=ASM-like phosphodiesterase 3a; Flags: Precursor [Rattus norvegicus]