Gene/Proteome Database (LMPD)

LMPD ID
LMP013132
Gene ID
295631
Species
Rattus norvegicus (Rat)
Gene Name
phospholipase A2 receptor 1
Gene Symbol
Pla2r1
Synonyms
Mrc2;
Alternate Names
secretory phospholipase A2 receptor; mannose receptor, C type 2;
Chromosome
3
Map Location
3q21

Proteins

secretory phospholipase A2 receptor precursor
Refseq ID NP_001094307
Protein GI 282154817
UniProt ID F1M495
mRNA ID NM_001100837
Length 1461
MAQWLAMLQLLWLQQLLLGVHQGSAQDLTHTQELALEWRDKGIFIIQSESLKTCIQAGKSVLTLENCTQPNEYMLWKWVSDNHLFNVGASGCLGLNISDLKRPLSLYECDSTLISLRWLCDRKTIVGPLQYKVQVNHSTVVAKKTPHKWSAYMPGGGDICEHLHRDIYTLKGNAHGMPCVFPFQFKGQWHHECIREGHKEHLLWCATTSRYEEDEKWGFCPDPTSTEIFCDAMWQRNDNSHICYQFNLLSSLSWNEAHSSCQMQGGALLSITDENEEAFIRKELSRVAKEVWTGLNQLDEMAGWQWSDGTPLSYLNWSQEVTAGPFVEYHCGTLKVASATWRSMDCESTLPYICKRHLNHTAEDILQKDSWKYHTTHCDPGWTPFNRKCYKLKKEKRTWQEALHSCQSDDSMLMDVTSLAEVELLVNLLGDENASETWIGLSSNKIPVSFAWSSGSSVIFTNWYLLEPRILPNRRQLCVSADQSDGRWKVKGCKETLPYICKKAGQVLEDEDSGCQAGWERHGKYCYKIDTVLRSFEQASGGYYCPPALLTITSRFEQAFITSLISSVARKDSYFWIALQDQNNTGEYTWKTMGQREPVQYTHWNAHQPSYHGGCVVLRGGSSFGRWEVKNCSDFKAMSLCKTPIKVWEKTEFEGRWPFHPCYMDWESETGLASCFKVFHSEKVLMKRSWREAEAFCEEFGAHLASFAHIEEENFVNKLLHSKFNWTQERQFWIGFNKRNPLNAGSWEWSDGSPVVSSFLDNAYFEEDAKNCAVYKANNTLLPSNCASKHEWICKIPRDVKPNFPVWYQYDAPWLFYQNAEYLFHTHPAEWATFEFVCGWLRSDFLTIYSAQEQEFIHSKIRALSKYGANWWIGLEDRRAGDQIHWSNGSPVIFQNWDKGRKGRMDSQRKRCVFMSAITGLWGTENCSVPMPSICKRVKIWVIEKEKPPTQHGTCPKGWLYFNYKCFLVTIPKDPRELKTWTGAQEFCAAKGGTLVSIESELEQAFITVNLFGQTTNVWIGLQSDNHENWVNGKPVVYSNWSPSDVINIPNYNTTEVQKRAPLCALMSSNPNFHFTGKWYFDDCGKKGYGFVCEKMQDTLENHVNVSDTYAVPSTLEYGNRTYKIIRANMTWYAAGKSCRMQGAELVSIPDVFHQSFLTVLLSRLGHAHWIGLSTPDNGLNFDWSDGTKSPFTYWKDEESASLGDCVFADTDGHWHGTACESHLQGAVCRVLTETKSFEHPVLCSETSVPWIRFKGHCYSFSTVLDSRSFEDAREFCKREGSNLLAIKDEAENLFLLEELLALGSSVQMVWLNAQLDNDNKTLRWFDGAATEQSNWGVRKPDMDHLKPHPCVVLRIPEGVWQSTPCEDKTGFICKVEAGIPAVTAHPEKGLSHSIMPVAAALALTIVLGILVLCLWIYKQNGGAILPRLTGSRGPYYPMSSFSMAHLEENILISDLEKNNQ
sig_peptide: 1..25 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2849 peptide sequence: MAQWLAMLQLLWLQQLLLGVHQGSA

Gene Information

Entrez Gene ID
295631
Gene Name
phospholipase A2 receptor 1
Gene Symbol
Pla2r1
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009986 IEA:Ensembl C cell surface
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0005886 ISS:UniProtKB C plasma membrane
GO:0043235 IEA:Ensembl C receptor complex
GO:0030246 IEA:InterPro F carbohydrate binding
GO:0043274 ISS:UniProtKB F phospholipase binding
GO:0004872 ISS:UniProtKB F receptor activity
GO:0001816 ISS:UniProtKB P cytokine production
GO:1900139 IEA:Ensembl P negative regulation of arachidonic acid secretion
GO:1900138 IEA:Ensembl P negative regulation of phospholipase A2 activity
GO:0090403 ISS:UniProtKB P oxidative stress-induced premature senescence
GO:0043517 ISS:UniProtKB P positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0090238 ISS:UniProtKB P positive regulation of arachidonic acid secretion
GO:0072593 ISS:UniProtKB P reactive oxygen species metabolic process
GO:0006898 ISS:UniProtKB P receptor-mediated endocytosis
GO:0090399 ISS:UniProtKB P replicative senescence

KEGG Pathway Links

KEGG Pathway ID Description
ko04145 Phagosome
rno04145 Phagosome
ko05152 Tuberculosis
rno05152 Tuberculosis

Domain Information

InterPro Annotations

Accession Description
IPR018378 C-type lectin, conserved site
IPR001304 C-type_lectin
IPR016186 C-type_lectin-like
IPR016187 C-type_lectin_fold
IPR000562 Fibronectin, type II, collagen-binding
IPR013806 Kringle-like fold
IPR000772 Ricin B lectin domain

UniProt Annotations

Entry Information

Gene Name
phospholipase A2 receptor 1
Protein Entry
F1M495_RAT
UniProt ID
F1M495
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP013132 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
282154817 RefSeq NP_001094307 1461 secretory phospholipase A2 receptor precursor

Identical Sequences to LMP013132 proteins

Reference Database Accession Length Protein Name
GI:282154817 GenBank EDM00377.1 1461 mannose receptor, C type 2 (predicted) [Rattus norvegicus]

Related Sequences to LMP013132 proteins

Reference Database Accession Length Protein Name
GI:282154817 GenBank EDM00377.1 1461 mannose receptor, C type 2 (predicted) [Rattus norvegicus]
GI:282154817 GenBank AEU43256.1 1487 Sequence 5 from patent US 8052970
GI:282154817 GenBank AEU43325.1 1487 Sequence 74 from patent US 8052970
GI:282154817 GenBank AEU43338.1 1487 Sequence 87 from patent US 8052970