Gene/Proteome Database (LMPD)

LMPD ID
LMP013154
Gene ID
298298
Species
Rattus norvegicus (Rat)
Gene Name
24-dehydrocholesterol reductase
Gene Symbol
Dhcr24
Alternate Names
delta(24)-sterol reductase; seladin-1; 3-beta-hydroxysterol delta-24-reductase;
Chromosome
5
Map Location
5q34

Proteins

delta(24)-sterol reductase precursor
Refseq ID NP_001073617
Protein GI 121949752
UniProt ID A1KXK4
mRNA ID NM_001080148
Length 516
MEPAVSLAVCALLFLLWVRVKGLEFVLIHQRWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVQDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKYRKTHKNIMINLMDILEVDTKKQIVRVEPLVSMGQVTALLNSIGWTLPVLPELDDLTVGGLIMGAGIESSSHKYGLFQHICTAYELILADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICEKFTHESQRLENHFVEGLLYSLDEAVIMTGVMTDDVEPSKLNSIGSYYKPWFFKHVENYLKTNREGLEYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCLSQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKGDEAELYVDIGAYGEPRVKHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLRKQLGCQDAFPEVYDKICKAARH
sig_peptide: 1..22 inference: non-experimental evidence, no additional details recorded note: Potential; propagated from UniProtKB/Swiss-Prot (Q5BQE6.2) calculated_mol_wt: 2416 peptide sequence: MEPAVSLAVCALLFLLWVRVKG mat_peptide: 23..516 product: Delta(24)-sterol reductase experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q5BQE6.2) calculated_mol_wt: 57647 peptide sequence: LEFVLIHQRWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVQDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKYRKTHKNIMINLMDILEVDTKKQIVRVEPLVSMGQVTALLNSIGWTLPVLPELDDLTVGGLIMGAGIESSSHKYGLFQHICTAYELILADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICEKFTHESQRLENHFVEGLLYSLDEAVIMTGVMTDDVEPSKLNSIGSYYKPWFFKHVENYLKTNREGLEYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCLSQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKGDEAELYVDIGAYGEPRVKHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLRKQLGCQDAFPEVYDKICKAARH

Gene Information

Entrez Gene ID
298298
Gene Name
24-dehydrocholesterol reductase
Gene Symbol
Dhcr24
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0008762 IEA:InterPro F UDP-N-acetylmuramate dehydrogenase activity
GO:0050660 IEA:InterPro F flavin adenine dinucleotide binding

KEGG Pathway Links

KEGG Pathway ID Description
M00101 Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol
rno01100 Metabolic pathways
ko00100 Steroid biosynthesis
rno00100 Steroid biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
5953924 Cholesterol biosynthesis
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins

Domain Information

InterPro Annotations

Accession Description
IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2
IPR006094 FAD linked oxidase, N-terminal
IPR016166 FAD-binding, type 2

UniProt Annotations

Entry Information

Gene Name
24-dehydrocholesterol reductase
Protein Entry
A1KXK4_RAT
UniProt ID
A1KXK4
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP013154 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
121949752 RefSeq NP_001073617 516 delta(24)-sterol reductase precursor

Identical Sequences to LMP013154 proteins

Reference Database Accession Length Protein Name
GI:121949752 GenBank AAS66628.1 516 3-beta-hydroxysterol delta 24 reductase [Rattus norvegicus]

Related Sequences to LMP013154 proteins

Reference Database Accession Length Protein Name
GI:121949752 GenBank AAS66628.1 516 3-beta-hydroxysterol delta 24 reductase [Rattus norvegicus]
GI:121949752 GenBank AAX29968.2 516 24-dehydrocholesterol reductase [Rattus norvegicus]
GI:121949752 GenBank EDL90471.1 516 rCG50449 [Rattus norvegicus]
GI:121949752 SwissProt Q5BQE6.2 516 RecName: Full=Delta(24)-sterol reductase; AltName: Full=24-dehydrocholesterol reductase; AltName: Full=3-beta-hydroxysterol delta-24-reductase; Flags: Precursor [Rattus norvegicus]