Gene/Proteome Database (LMPD)
Proteins
| ubiquinone biosynthesis monooxygenase COQ6 precursor | |
|---|---|
| Refseq ID | NP_001011983 |
| Protein GI | 58865534 |
| UniProt ID | Q68FU7 |
| mRNA ID | NM_001011983 |
| Length | 476 |
| MAARIGPMAGLLCVRWWSTAQLAARGGPLVACRRWTSSSTDSVYDVVVSGGGMVGSAMACALGHDIHFHDKKILLLEAGPKKTLEKLSETYSNRVSSISLGSTTLLSSFGAWDHICNMRCKAFRRMQVWDSCSEALIMFDKDNLDDMGYIVENDVIMHAITKQLEAVADRVKVLYESKAVGYAWPGPFSLADSSPWVHITLGDGSTLQTKLLIGADGHNSGVRQAAGIQNVGWNYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHAHAAELVSMHEEEFVDAINSAFWSDVHHTDFVDSASAMVHHAVALLKPTKVSARQLPPSVAKVDAKSRALFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLIHYLSTAAFNGKDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSTTPLVLLRTWGLQATNAVSPLKEQIMAFASR | |
| sig_peptide: 1..23 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2503 peptide sequence: MAARIGPMAGLLCVRWWSTAQLA | |
Gene Information
Entrez Gene ID
Gene Name
coenzyme Q6 monooxygenase
Gene Symbol
Species
Rattus norvegicus
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005794 | IEA:UniProtKB-KW | C | Golgi apparatus |
| GO:0042995 | IEA:UniProtKB-KW | C | cell projection |
| GO:0005739 | IEA:Ensembl | C | mitochondrion |
| GO:0050660 | IEA:InterPro | F | flavin adenine dinucleotide binding |
| GO:0016709 | IEA:InterPro | F | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| GO:0006744 | IEA:UniProtKB-UniPathway | P | ubiquinone biosynthetic process |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| rno01100 | Metabolic pathways |
| ko00130 | Ubiquinone and other terpenoid-quinone biosynthesis |
| rno00130 | Ubiquinone and other terpenoid-quinone biosynthesis |
| M00128 | Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone |
REACTOME Pathway Links
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR003042 | Aromatic-ring hydroxylase-like |
| IPR002938 | Monooxygenase, FAD-binding |
| IPR010971 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/UbiI/COQ6 |
| IPR018168 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site |
| IPR000689 | Ubiquinone biosynthesis monooxygenase, COQ6-type |
UniProt Annotations
Entry Information
Comments
| Comment Type | Description |
|---|---|
| Cofactor | Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence= ; |
| Pathway | Cofactor biosynthesis; ubiquinone biosynthesis. |
| Similarity | Belongs to the UbiH/COQ6 family |
| Subcellular Location | Golgi apparatus . Cell projection . Note=Localizes to podocyte cell processes. |
| Subunit | Interacts with ADCK4 and COQ7 |
| Tissue Specificity | In the kidney, expressed almost exclusively in glomerular podocytes. In the inner ear, expressed in the spiral ganglion, as well as in stria vascularis and spiral ligament cells |
Identical and Related Proteins
Unique RefSeq proteins for LMP013171 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 58865534 | RefSeq | NP_001011983 | 476 | ubiquinone biosynthesis monooxygenase COQ6 precursor |
Identical Sequences to LMP013171 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:58865534 | GenBank | AAH79342.1 | 476 | Coenzyme Q6 homolog (yeast) [Rattus norvegicus] |
| GI:58865534 | GenBank | EDL81500.1 | 476 | rCG20705, isoform CRA_c [Rattus norvegicus] |
| GI:58865534 | SwissProt | Q68FU7.1 | 476 | RecName: Full=Ubiquinone biosynthesis monooxygenase COQ6 [Rattus norvegicus] |
Related Sequences to LMP013171 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:58865534 | GenBank | AAH79342.1 | 476 | Coenzyme Q6 homolog (yeast) [Rattus norvegicus] |
| GI:58865534 | GenBank | AAI32171.1 | 476 | Coenzyme Q6 homolog (yeast) [Mus musculus] |
| GI:58865534 | GenBank | EDL81500.1 | 476 | rCG20705, isoform CRA_c [Rattus norvegicus] |
| GI:58865534 | SwissProt | Q68FU7.1 | 476 | RecName: Full=Ubiquinone biosynthesis monooxygenase COQ6 [Rattus norvegicus] |