Gene/Proteome Database (LMPD)
Proteins
long-chain-fatty-acid--CoA ligase ACSBG2 | |
---|---|
Refseq ID | NP_001073565 |
Protein GI | 121583863 |
UniProt ID | A1L1K7 |
mRNA ID | NM_001080096 |
Length | 667 |
MTQEKKAEDPDRGMDTTSAAPRLWSTHCDGEVLLRLSKHGPGHETPMTIPELFQESVERFGAYPALASKNGKKWDTLTFSQYYDVCRKAARSLIKLGLQRFHGVGILGFNSVEWVVAALGAILAGGLCVGIYATNSAEACQYVIKQANVNVLIVENDQQLQKILSIPPDKMETVKAIVQYRLPLMENSTNLYSWQDFMELGNAIPNIQLDRVILSQKANQCAVIIYTSGTTGSPKGVMLSHDNITWTAGAMAREIELIHVSGKQDTIVSYLPLSHIAAQLMDIWIPIKVGVLTFFAQPDALRGTLVYTLQEVKPTYFLGVPRVWEKMQDTIKENVAKSSNLRKKAFAWAKMLGLKVNTKKMLGKRDIPMNYRMAKALVFTKVRTSLGLDNCHTFFSGASPLSQDVSEFFLSLDIPIGEIYGMTECSGPHTVSCKSIYRVLSCGKVLNGCKNMLYKQNKDGVGEVCMWGRHVFMGYLGKEDATLEVLDEDGWLHSGDIGRLDSHDFLYITGRIKEVLITAGGENIWPIPIETLVKEKIPIISHAMLVGDKAKFLSMLLTLKCETDQMSGEPLDKLNLEAISFCQMLGSQAVTVSDILKIRDPVVYTAIQYGIDIVNQQAVSDSHRIRKWIILEKDFSIQGGELGPTSKLKRDLITQKYKAQIDNMYSS |
Gene Information
Entrez Gene ID
Gene Name
acyl-CoA synthetase bubblegum family member 2
Gene Symbol
Species
Rattus norvegicus
Gene Ontology (GO Annotations)
GO ID | Source | Type | Description |
---|---|---|---|
GO:0005829 | IEA:Ensembl | C | cytosol |
GO:0016020 | IEA:UniProtKB-KW | C | membrane |
GO:0005739 | IEA:Ensembl | C | mitochondrion |
GO:0047617 | IEA:Ensembl | F | acyl-CoA hydrolase activity |
GO:0005524 | IEA:UniProtKB-KW | F | ATP binding |
GO:0004467 | IEA:UniProtKB-EC | F | long-chain fatty acid-CoA ligase activity |
GO:0030154 | IEA:UniProtKB-KW | P | cell differentiation |
GO:0007275 | IEA:UniProtKB-KW | P | multicellular organismal development |
GO:0007283 | IEA:UniProtKB-KW | P | spermatogenesis |
KEGG Pathway Links
KEGG Pathway ID | Description |
---|---|
ko04920 | Adipocytokine signaling pathway |
rno04920 | Adipocytokine signaling pathway |
M00086 | beta-Oxidation, acyl-CoA synthesis |
ko00061 | Fatty acid biosynthesis |
rno00061 | Fatty acid biosynthesis |
ko00071 | Fatty acid degradation |
rno00071 | Fatty acid degradation |
ko01212 | Fatty acid metabolism |
rno01212 | Fatty acid metabolism |
rno01100 | Metabolic pathways |
ko03320 | PPAR signaling pathway |
rno03320 | PPAR signaling pathway |
Domain Information
UniProt Annotations
Entry Information
Gene Name
acyl-CoA synthetase bubblegum family member 2
Protein Entry
ACBG2_RAT
UniProt ID
Species
Rat
Comments
Comment Type | Description |
---|---|
Catalytic Activity | ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA. |
Function | Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Has increased ability to activate oleic and linoleic acid. May play a role in spermatogenesis (By similarity) |
Similarity | Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily |
Subcellular Location | Cytoplasm . Membrane {ECO:0000250}; Peripheral membrane protein . |
Identical and Related Proteins
Unique RefSeq proteins for LMP013202 (as displayed in Record Overview)
Protein GI | Database | Accession | Length | Protein Name |
---|---|---|---|---|
121583863 | RefSeq | NP_001073565 | 667 | long-chain-fatty-acid--CoA ligase ACSBG2 |
Identical Sequences to LMP013202 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:121583863 | GenBank | AAI29111.1 | 667 | Acyl-CoA synthetase bubblegum family member 2 [Rattus norvegicus] |
GI:121583863 | SwissProt | A1L1K7.1 | 667 | RecName: Full=Long-chain-fatty-acid--CoA ligase ACSBG2; AltName: Full=Acyl-CoA synthetase bubblegum family member 2 [Rattus norvegicus] |
Related Sequences to LMP013202 proteins
Reference | Database | Accession | Length | Protein Name |
---|---|---|---|---|
GI:121583863 | GenBank | AAI29111.1 | 667 | Acyl-CoA synthetase bubblegum family member 2 [Rattus norvegicus] |
GI:121583863 | GenBank | EDL83602.1 | 698 | similar to lipidosin [Rattus norvegicus] |
GI:121583863 | RefSeq | XP_006244373.1 | 698 | PREDICTED: long-chain-fatty-acid--CoA ligase ACSBG2 isoform X1 [Rattus norvegicus] |
GI:121583863 | SwissProt | A1L1K7.1 | 667 | RecName: Full=Long-chain-fatty-acid--CoA ligase ACSBG2; AltName: Full=Acyl-CoA synthetase bubblegum family member 2 [Rattus norvegicus] |