Gene/Proteome Database (LMPD)

LMPD ID
LMP013203
Gene ID
301173
Species
Rattus norvegicus (Rat)
Gene Name
phospholipase C-like 2
Gene Symbol
Plcl2
Alternate Names
inactive phospholipase C-like protein 2;
Chromosome
9
Map Location
9q11
EC Number
3.1.4.11

Proteins

inactive phospholipase C-like protein 2
Refseq ID NP_001100350
Protein GI 157821257
UniProt ID F1M324
mRNA ID NM_001106880
Length 1001
MPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWEPSKKDSEKAKIDIKSIKEVRTGKNTDIFRSNGISEQISEDCAFSVIYGENYESLDLVANSADVANIWVTGLRYLISYGKHTLDMLESSQDNMRTCWVSQMFSEIDVDDLGHITLCNAVQCIRNLNPGLKTSKIELKFKELHKSKDKTGTEITKEEFVEVFHELCTRPEIYFLLVQFSSNKEFLDTKDLMMFLEAEQGVAHINEEISLEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKKVCQDMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSIKQQKVMVQHMKKILGDKLYTTSPNMEESYLPSPDVLKGKILIKAKKLSSNCSGVEGDVTDEDEGAEMSQRMGKENVEQPNHVPVKRFQLCKDLSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYANENPGDFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGNCGYVLRPAIMREEVSFFSANTKDSVPGVSPQLLHIKIISGQNFPKPKGSGAKGDVVDPYVYVEIHGIPADCAEQRTKTVNQNGDAPMFDESFEFQINLPELAMVRFVVLDDDYIGDEFIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAITNRRGGGKPHKRGLSVRKGKKSREYASLRTLWIKTVDEVFKNAQPPIRDATDLRENMQNAVVSFKELCGLSSVANLMQCMLAVSPRFLGPDNTPLVVLNLSEPYPTMELQAIVPEVLKKIVTTYDMMIQSLKALIENADAVYEKIVHCQKAAMEFHEHLHSIGTKEGLKERKLQKAVESFTWNITILKGQADLLKYAKNETLENLKQIHYAAVSCGLNKPGTENSEAQKPRRSLEVIPEKTSDENGD

Gene Information

Entrez Gene ID
301173
Gene Name
phospholipase C-like 2
Gene Symbol
Plcl2
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004435 IEA:UniProtKB-EC F phosphatidylinositol phospholipase C activity
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0002322 IEA:Ensembl P B cell proliferation involved in immune response
GO:0002337 IEA:Ensembl P B-1a B cell differentiation
GO:0007214 IEA:Ensembl P gamma-aminobutyric acid signaling pathway
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process
GO:0050859 IEA:Ensembl P negative regulation of B cell receptor signaling pathway
GO:1900122 IEA:Ensembl P positive regulation of receptor binding
GO:0033135 IEA:Ensembl P regulation of peptidyl-serine phosphorylation
GO:0032228 IEA:Ensembl P regulation of synaptic transmission, GABAergic

Domain Information

InterPro Annotations

Accession Description
IPR000008 C2 domain
IPR011992 EF-hand domain pair
IPR028383 Inactive phospholipase C-like protein 2
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
IPR001192 Phosphoinositide phospholipase C family
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like
IPR001849 Pleckstrin homology domain
IPR011993 Pleckstrin homology-like domain

UniProt Annotations

Entry Information

Gene Name
phospholipase C-like 2
Protein Entry
F1M324_RAT
UniProt ID
F1M324
Species
Rat

Comments

Comment Type Description
Catalytic Activity 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
Similarity Contains 1 C2 domain
Similarity Contains 1 PH domain
Similarity Contains 1 PI-PLC X-box domain
Similarity Contains 1 PI-PLC Y-box domain
Similarity Contains C2 domain
Similarity Contains Cdomain
Similarity Contains PH domain
Similarity Contains PI-PLC X-box domain
Similarity Contains PI-PLC Y-box domain

Identical and Related Proteins

Unique RefSeq proteins for LMP013203 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
157821257 RefSeq NP_001100350 1001 inactive phospholipase C-like protein 2

Identical Sequences to LMP013203 proteins

Reference Database Accession Length Protein Name
GI:157821257 GenBank EDL83023.1 1001 phospholipase C-like 2 (predicted) [Rattus norvegicus]

Related Sequences to LMP013203 proteins

Reference Database Accession Length Protein Name
GI:157821257 EMBL CBU96763.1 1128 unnamed protein product [Mus musculus]
GI:157821257 GenBank AAH27746.1 1128 Plcl2 protein [Mus musculus]
GI:157821257 GenBank EDL83023.1 1001 phospholipase C-like 2 (predicted) [Rattus norvegicus]
GI:157821257 GenBank AGX54751.1 1128 Sequence 9858 from patent US 8541208