Gene/Proteome Database (LMPD)
Proteins
| 24-hydroxycholesterol 7-alpha-hydroxylase | |
|---|---|
| Refseq ID | NP_001100363 |
| Protein GI | 157818125 |
| UniProt ID | D4AE09 |
| mRNA ID | NM_001106893 |
| Length | 465 |
| MGIMELFSPIAIAVLGSCVLFLFSRWKNLRGPPCIQGWIPWIGAGFEFGKAPLEFIEKARIKYGPVFTVFAVGKRMTFVTEEEGINVLLKSKHVDFELAVQRPLYHTAWIPKNIFFALHEKLYVLMKGKMGTFNTHHFTGQLTEEFHDQLEGLGTHGTMDLNDFVRYLLYPATLNTLFMKGLFLTDKRKIKEFYQHFKTYDEGFEYGSQLPEWLLRNWSKSKRWLLALFEKNIGDIKTHGSAGHSETLLQAVLGMVETETRLHSPNYGLVMLWASLANAAPIAFWTLAYILSHPDLHRTIVESISSVFGTAGKDKIQVSENDLKKLLLIKWCILESIRLRAPGVITRKVVKPVKILNHTVPSGDLLMLSPFWLHRNPKYFPEPESFKPERWKEANLDKYIFLDYFMAFGGGKFQCPGRWFALLEIQLCIILVLYKYECSLLDPLPKQAKFSSFGGCPPASREMPN | |
Gene Information
Entrez Gene ID
Gene Name
cytochrome P450, family 39, subfamily a, polypeptide 1
Gene Symbol
Species
Rattus norvegicus
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0020037 | IEA:InterPro | F | heme binding |
| GO:0005506 | IEA:InterPro | F | iron ion binding |
| GO:0008396 | IEA:Ensembl | F | oxysterol 7-alpha-hydroxylase activity |
| GO:0008387 | IEA:Ensembl | F | steroid 7-alpha-hydroxylase activity |
| GO:0006699 | IEA:Ensembl | P | bile acid biosynthetic process |
| GO:0006707 | IEA:Ensembl | P | cholesterol catabolic process |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| ko00120 | Primary bile acid biosynthesis |
| rno00120 | Primary bile acid biosynthesis |
REACTOME Pathway Links
| REACTOME Pathway ID | Description |
|---|---|
| 5953720 | Bile acid and bile salt metabolism |
| 5953258 | Biological oxidations |
| 5953485 | Cytochrome P450 - arranged by substrate type |
| 5953932 | Endogenous sterols |
| 5953250 | Metabolism |
| 5953289 | Metabolism of lipids and lipoproteins |
| 5953326 | Phase 1 - Functionalization of compounds |
| 5953930 | Synthesis of bile acids and bile salts |
| 5953933 | Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
Domain Information
UniProt Annotations
Entry Information
Gene Name
cytochrome P450, family 39, subfamily a, polypeptide 1
Protein Entry
D4AE09_RAT
UniProt ID
Species
Rat
Identical and Related Proteins
Unique RefSeq proteins for LMP013204 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 157818125 | RefSeq | NP_001100363 | 465 | 24-hydroxycholesterol 7-alpha-hydroxylase |
Identical Sequences to LMP013204 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:157818125 | GenBank | EDM18705.1 | 465 | cytochrome P450, family 39, subfamily a, polypeptide 1 (predicted), isoform CRA_a [Rattus norvegicus] |
Related Sequences to LMP013204 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:157818125 | GenBank | EDM18705.1 | 465 | cytochrome P450, family 39, subfamily a, polypeptide 1 (predicted), isoform CRA_a [Rattus norvegicus] |
| GI:157818125 | RefSeq | XP_006244666.1 | 482 | PREDICTED: 24-hydroxycholesterol 7-alpha-hydroxylase isoform X3 [Rattus norvegicus] |
| GI:157818125 | RefSeq | XP_006244667.1 | 470 | PREDICTED: 24-hydroxycholesterol 7-alpha-hydroxylase isoform X4 [Rattus norvegicus] |
| GI:157818125 | RefSeq | XP_008765077.1 | 483 | PREDICTED: 24-hydroxycholesterol 7-alpha-hydroxylase isoform X2 [Rattus norvegicus] |