Gene/Proteome Database (LMPD)

LMPD ID
LMP013216
Gene ID
302705
Species
Rattus norvegicus (Rat)
Gene Name
membrane-bound transcription factor peptidase, site 2
Gene Symbol
Mbtps2
Synonyms
LRRGT00063;
Alternate Names
membrane-bound transcription factor site-2 protease; membrane-bound transcription factor protease, site 2;
Chromosome
X
Map Location
Xq21

Proteins

membrane-bound transcription factor site-2 protease
Refseq ID NP_001030179
Protein GI 78042482
UniProt ID D3ZDS6
mRNA ID NM_001035007
Length 519
MIPVSLVVVVVGGWTAVYLADLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTSIFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSPYSSSSSSSSSSSSSSSSSSSSSSSLHNDQVLQVVVPGINLPVNQLTYFFAAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQIGYCISASTLQQLSFPVRAYKRLDGSTECCNNHSLTDVCFSYRNNFNKRLHTCLPARKAVEATQVCRSNKDCKSSSSSSFCIVPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTVSITSFIPRFNFLSIDLPVIVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLGGSVLLAANVTLGLWMVTAR

Gene Information

Entrez Gene ID
302705
Gene Name
membrane-bound transcription factor peptidase, site 2
Gene Symbol
Mbtps2
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:Ensembl C cytoplasm
GO:0016020 IEA:InterPro C membrane
GO:0004222 IEA:InterPro F metalloendopeptidase activity

KEGG Pathway Links

KEGG Pathway ID Description
ko04141 Protein processing in endoplasmic reticulum
rno04141 Protein processing in endoplasmic reticulum

REACTOME Pathway Links

REACTOME Pathway ID Description
5954162 ATF6-alpha activates chaperones
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins
5953345 Metabolism of proteins
5954497 Regulation of cholesterol biosynthesis by SREBP (SREBF)
5954163 Unfolded Protein Response (UPR)

Domain Information

InterPro Annotations

Accession Description
IPR001193 Membrane-bound transcription factor site-2 protease
IPR001478 PDZ domain
IPR008915 Peptidase_M50

UniProt Annotations

Entry Information

Gene Name
membrane-bound transcription factor peptidase, site 2
Protein Entry
D3ZDS6_RAT
UniProt ID
D3ZDS6
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP013216 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
78042482 RefSeq NP_001030179 519 membrane-bound transcription factor site-2 protease

Identical Sequences to LMP013216 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP013216 proteins

Reference Database Accession Length Protein Name
GI:78042482 DBBJ BAG11437.1 519 membrane-bound transcription factor site-2 protease, partial [synthetic construct]
GI:78042482 GenBank AAC51937.1 519 S2P [Homo sapiens]
GI:78042482 GenBank EAW98982.1 519 membrane-bound transcription factor peptidase, site 2 [Homo sapiens]
GI:78042482 SwissProt O43462.1 519 RecName: Full=Membrane-bound transcription factor site-2 protease; AltName: Full=Endopeptidase S2P; AltName: Full=Sterol regulatory element-binding proteins intramembrane protease; Short=SREBPs intramembrane protease [Homo sapiens]