Gene/Proteome Database (LMPD)

LMPD ID
LMP013221
Gene ID
Species
Rattus norvegicus (Rat)
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class S
Gene Symbol
Alternate Names
GPI transamidase component PIG-S; phosphatidylinositol glycan, class S; phosphatidylinositol-glycan biosynthesis class S protein;
Chromosome
10
Map Location
10q25

Proteins

GPI transamidase component PIG-S
Refseq ID NP_001006602
Protein GI 54633340
UniProt ID Q5XI31
mRNA ID NM_001006602
Length 555
MATAGAAATDLEVVRGKRAALFFAAVAILLGLPLWWKTTETYRAPLPYSEISGLNALQLRLMVPVTVVFTRDSVPLDDQEKLPFTVVHEREIPLKYKMKIKCRFQKAYRRALEHEEEALSLGSVHEAEALLAEPEKQAEGSLTVYVISEHSSLLPQDMMSYIGPERTAIVRGMIHREAFNIIGRRIIHVAQAMSLTEDVLAAALADHLPEDKWSSDKRRPLKSSLGYEITFSLLNPDPKSHDVHWDIEEGVQRYVQPFLNRLSAAGNFSVDSQILYYAMLGVNPRFDPASSSYSLAMHSLPHVINPVESRLGSSAASLYPVLNFLLYVPELAHSPLYIQDKDGAPVATNAFHSPRWGGIMVYNVDPKIYNASELPVRVEVDMAQVMEVFLAQLRLLFGIAQPQVPPKCLLSGPKSEGLMTWELDRLLWARSVENLATATTTLTSLAQLLGKISNIVIKDDVASEVYRAVAAVQKAAEALALGHLSSAFAASQEAVTSSERAFFDPSLLHLLYFPDDQKFAIYIPLFLPMAVPILLSLVKIFLETHKSWKKPEKID

Gene Information

Entrez Gene ID
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class S
Gene Symbol
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0042765 IEA:InterPro C GPI-anchor transamidase complex
GO:0003923 IEA:Ensembl F GPI-anchor transamidase activity
GO:0016255 IEA:InterPro P attachment of GPI anchor to protein

KEGG Pathway Links

KEGG Pathway ID Description
ko00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
rno00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
rno01100 Metabolic pathways

REACTOME Pathway Links

REACTOME Pathway ID Description
5953740 Attachment of GPI anchor to uPAR
5953345 Metabolism of proteins
5953735 Post-translational modification: synthesis of GPI-anchored proteins
5953728 Post-translational protein modification

Domain Information

InterPro Annotations

Accession Description
IPR019540 Phosphatidylinositol-glycan biosynthesis class S protein

UniProt Annotations

Entry Information

Gene Name
phosphatidylinositol glycan anchor biosynthesis, class S
Protein Entry
PIGS_RAT
UniProt ID
Species
Rat

Comments

Comment Type Description
Function Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates (By similarity)
Pathway Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
Similarity Belongs to the PIGS family
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein .
Subunit Forms a complex with PIGK/GPI8, PIGT, PIGU and GAA1

Identical and Related Proteins

Unique RefSeq proteins for LMP013221 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
54633340 RefSeq NP_001006602 555 GPI transamidase component PIG-S

Identical Sequences to LMP013221 proteins

Reference Database Accession Length Protein Name
GI:54633340 GenBank AAH83862.1 555 Phosphatidylinositol glycan anchor biosynthesis, class S [Rattus norvegicus]
GI:54633340 GenBank EDM05348.1 555 phosphatidylinositol glycan, class S [Rattus norvegicus]
GI:54633340 SwissProt Q5XI31.3 555 RecName: Full=GPI transamidase component PIG-S; AltName: Full=Phosphatidylinositol-glycan biosynthesis class S protein [Rattus norvegicus]

Related Sequences to LMP013221 proteins

Reference Database Accession Length Protein Name
GI:54633340 GenBank AAH83862.1 555 Phosphatidylinositol glycan anchor biosynthesis, class S [Rattus norvegicus]
GI:54633340 GenBank EDM05348.1 555 phosphatidylinositol glycan, class S [Rattus norvegicus]
GI:54633340 SwissProt Q6PD26.3 555 RecName: Full=GPI transamidase component PIG-S; AltName: Full=Phosphatidylinositol-glycan biosynthesis class S protein [Mus musculus]
GI:54633340 SwissProt Q5XI31.3 555 RecName: Full=GPI transamidase component PIG-S; AltName: Full=Phosphatidylinositol-glycan biosynthesis class S protein [Rattus norvegicus]