Gene/Proteome Database (LMPD)
Proteins
| arylsulfatase G precursor | |
|---|---|
| Refseq ID | NP_001041342 |
| Protein GI | 114145555 |
| UniProt ID | Q32KJ9 |
| mRNA ID | NM_001047877 |
| Length | 526 |
| MGWLFLKVLLVGMVFSGLLYPFVDFSISGETRAPRPNIVIILADDMGWGDLGANWAETKDTTNLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTHNFAVTSVGGLPLNETTLAEVLQQAGYVTAMIGKWHLGHHGSYHPSFRGFDYYFGIPYSNDMGCTDNPGYNYPPCPACPQSDGRWRNPDRDCYTDVALPLYENLNIVEQPVNLSGLAQKYAERAVEFIEQASTSGRPFLLYVGLAHMHVPLSVTPPLANPQSQRLYRASLQEMDSLVGQIKDKVDHVAKENTLLWFAGDNGPWAQKCELAGSMGPFSGLWQTHQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSLLDIFPTVIALAGASLPPNRKFDGVDVSEVLFGKSQTGHRVLFHPNSGAAGEYGALQTVRLDRYKAFYITGGAKACDGGVGPEQHHVSPLIFNLEDDAAESSPLQKGSPEYQELLPKVTRVLADVLQDIADDNSSQADYTQDPSVTPCCNPYQITCRCQPGE | |
| sig_peptide: 1..16 inference: non-experimental evidence, no additional details recorded note: Potential; propagated from UniProtKB/Swiss-Prot (Q32KJ9.1) calculated_mol_wt: 1840 peptide sequence: MGWLFLKVLLVGMVFS mat_peptide: 17..526 product: Arylsulfatase G experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q32KJ9.1) calculated_mol_wt: 55447 peptide sequence: GLLYPFVDFSISGETRAPRPNIVIILADDMGWGDLGANWAETKDTTNLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTHNFAVTSVGGLPLNETTLAEVLQQAGYVTAMIGKWHLGHHGSYHPSFRGFDYYFGIPYSNDMGCTDNPGYNYPPCPACPQSDGRWRNPDRDCYTDVALPLYENLNIVEQPVNLSGLAQKYAERAVEFIEQASTSGRPFLLYVGLAHMHVPLSVTPPLANPQSQRLYRASLQEMDSLVGQIKDKVDHVAKENTLLWFAGDNGPWAQKCELAGSMGPFSGLWQTHQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSLLDIFPTVIALAGASLPPNRKFDGVDVSEVLFGKSQTGHRVLFHPNSGAAGEYGALQTVRLDRYKAFYITGGAKACDGGVGPEQHHVSPLIFNLEDDAAESSPLQKGSPEYQELLPKVTRVLADVLQDIADDNSSQADYTQDPSVTPCCNPYQITCRCQPGE | |
Gene Information
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005783 | IEA:Ensembl | C | endoplasmic reticulum |
| GO:0005615 | IEA:Ensembl | C | extracellular space |
| GO:0005764 | ISS:UniProtKB | C | lysosome |
| GO:0004065 | ISS:UniProtKB | F | arylsulfatase activity |
| GO:0046872 | IEA:UniProtKB-KW | F | metal ion binding |
| GO:0006790 | IEA:Ensembl | P | sulfur compound metabolic process |
KEGG Pathway Links
REACTOME Pathway Links
| REACTOME Pathway ID | Description |
|---|---|
| 5954485 | Glycosphingolipid metabolism |
| 5953250 | Metabolism |
| 5953289 | Metabolism of lipids and lipoproteins |
| 5953345 | Metabolism of proteins |
| 5953727 | PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 5953728 | Post-translational protein modification |
| 5954267 | Sphingolipid metabolism |
| 5954489 | The activation of arylsulfatases |
Domain Information
UniProt Annotations
Entry Information
Comments
| Comment Type | Description |
|---|---|
| Cofactor | Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence= ; Note=Binds 1 Ca(2+) ion per subunit. ; |
| Function | Displays arylsulfatase activity with pseudosubstrates at acidic pH, such as p-nitrocatechol sulfate |
| Ptm | Glycosylated |
| Ptm | N-glycosylated |
| Ptm | The conversion to 3-oxoalanine (also known as C- formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity |
| Similarity | Belongs to the sulfatase family |
| Subcellular Location | Lysosome. Note=Previously observed endoplasmic reticulum localization is most likely due to folding/maturation problems for overexpressed proteins |
Identical and Related Proteins
Unique RefSeq proteins for LMP013229 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 114145555 | RefSeq | NP_001041342 | 526 | arylsulfatase G precursor |
Identical Sequences to LMP013229 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:114145555 | RefSeq | XP_006247669.1 | 526 | PREDICTED: arylsulfatase G isoform X1 [Rattus norvegicus] |
| GI:114145555 | RefSeq | XP_006247670.1 | 526 | PREDICTED: arylsulfatase G isoform X1 [Rattus norvegicus] |
| GI:114145555 | RefSeq | XP_008766590.1 | 526 | PREDICTED: arylsulfatase G isoform X1 [Rattus norvegicus] |
| GI:114145555 | RefSeq | XP_008766591.1 | 526 | PREDICTED: arylsulfatase G isoform X1 [Rattus norvegicus] |
Related Sequences to LMP013229 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:114145555 | GenBank | EDM06469.1 | 526 | arylsulfatase G [Rattus norvegicus] |
| GI:114145555 | RefSeq | XP_008766590.1 | 526 | PREDICTED: arylsulfatase G isoform X1 [Rattus norvegicus] |
| GI:114145555 | RefSeq | XP_008766591.1 | 526 | PREDICTED: arylsulfatase G isoform X1 [Rattus norvegicus] |
| GI:114145555 | SwissProt | Q32KJ9.1 | 526 | RecName: Full=Arylsulfatase G; Short=ASG; Flags: Precursor [Rattus norvegicus] |