Gene/Proteome Database (LMPD)
LMPD ID
LMP013257
Gene ID
Species
Rattus norvegicus (Rat)
Gene Name
solute carrier family 10, member 4
Gene Symbol
Alternate Names
sodium/bile acid cotransporter 4; bile acid transporter Slc10a4; Na(+)/bile acid cotransporter 4; solute carrier family 10 (sodium/bile acid cotransporter family), member 4;
Chromosome
14
Map Location
14p11
Proteins
| sodium/bile acid cotransporter 4 | |
|---|---|
| Refseq ID | NP_001008555 |
| Protein GI | 56676356 |
| UniProt ID | Q5PT56 |
| mRNA ID | NM_001008555 |
| Length | 437 |
| MDGLDNTTRLLAPSSLLPDNLTLSPNASSTSASTLSPLPVTSSPSPGLSLAPTPSIGFSPDLTPTPEPTSSSLAGGVAGQDSSTFPRPWIPHEPPFWDTPLNHGLNVFVGAALCITMLGLGCTVDVNHFGAHVRRPVGALLAALCQFGFLPLLAFLLALAFKLDEVAAVAVLLCGCCPGGNLSNLMSLLVDGDMNLSIIMTISSTLLALVLMPLCLWIYSRAWINTPLVQLLPLGAVTLTLCSTLIPIGLGVFIRYKYNRVADYIVKVSLCSLLVTLVVLFIMTGTMLGPELLASIPAAVYVVAIFMPLAGYASGYGLATLFHLPPNCKRTVCLETGSQNVQLCTAILKLAFPPRFIGSMYMFPLLYALFQSAEAGVFVLIYKMYGSEILHKREALDEDDDTDISYKKLKEEELADTSYGTVGTDDLVLMETTQTSL | |
Gene Information
Entrez Gene ID
Gene Name
solute carrier family 10, member 4
Gene Symbol
Species
Rattus norvegicus
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
| GO:0005886 | IEA:UniProtKB-KW | C | plasma membrane |
| GO:0008508 | IEA:InterPro | F | bile acid:sodium symporter activity |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR002657 | Bile acid:sodium symporter/arsenical resistance protein Acr3 |
UniProt Annotations
Entry Information
Comments
| Comment Type | Description |
|---|---|
| Function | Transporter for bile acids |
| Ptm | Activated following N-terminal proteolytic cleavage by thrombin and/or proteases |
| Similarity | Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family |
| Subcellular Location | Cell membrane ; Multi-pass membrane protein . |
| Tissue Specificity | Mainly expressed in the central nervous system cholinergic neurons. Expressed (at protein level) in motor regions of the spinal cord and rhombencephalon, in mesopontine cholinergic neurons, the medial habenula, cholinergic areas of the forebrain, and the gut myenteric plexus |
Identical and Related Proteins
Unique RefSeq proteins for LMP013257 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 56676356 | RefSeq | NP_001008555 | 437 | sodium/bile acid cotransporter 4 |
Identical Sequences to LMP013257 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:56676356 | GenBank | AAV80706.1 | 437 | SLC10A4 [Rattus norvegicus] |
| GI:56676356 | GenBank | AAW30131.1 | 437 | bile acid transporter Slc10a4 [Rattus norvegicus] |
| GI:56676356 | SwissProt | Q5PT56.1 | 437 | RecName: Full=Sodium/bile acid cotransporter 4; AltName: Full=Na(+)/bile acid cotransporter 4; AltName: Full=Solute carrier family 10 member 4 [Rattus norvegicus] |
Related Sequences to LMP013257 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:56676356 | DBBJ | BAE28763.1 | 437 | unnamed protein product [Mus musculus] |
| GI:56676356 | GenBank | AAV80706.1 | 437 | SLC10A4 [Rattus norvegicus] |
| GI:56676356 | GenBank | AAW30131.1 | 437 | bile acid transporter Slc10a4 [Rattus norvegicus] |
| GI:56676356 | SwissProt | Q5PT56.1 | 437 | RecName: Full=Sodium/bile acid cotransporter 4; AltName: Full=Na(+)/bile acid cotransporter 4; AltName: Full=Solute carrier family 10 member 4 [Rattus norvegicus] |