Gene/Proteome Database (LMPD)

LMPD ID
LMP013299
Gene ID
Species
Rattus norvegicus (Rat)
Gene Name
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
Gene Symbol
Alternate Names
pleckstrin homology domain-containing family A member 4; PEPP-1; PH domain-containing family A member 4; phosphoinositol 3-phosphate-binding protein 1; pleckstrin homology domain containing family A member 4;
Chromosome
1
Map Location
1q22
Summary
human homolog is a phosphatidylinositol-three-phosphate-binding protein [RGD, Feb 2006]
Orthologs

Proteins

pleckstrin homology domain-containing family A member 4
Refseq ID NP_954532
Protein GI 40018570
UniProt ID P60669
mRNA ID NM_199101
Length 779
MEQGRPRSSLSLTSSASTVSSLSSLSAKKPTRVVHKVHAFGKRNNALRRDPNLPVHIRGWLHKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYSVRPDGPGAPRGRRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGKASRAEGEDCGLPRSPARPRPGEGPGGPGGPPEVNRREEGRTSESPEVAPLSRGPGRHEMHAPGSSADLQPDTWSRRTRSPEPFSPLSRPPSPLSLPRPRSAPVRRPPLSAGDISFPARPHTPLSRIDVRPPLDWGPQRQTLSRPPIPRRGPFSEAGGGRPPRSPQLRTPEHRTQSTQVSSGSSTYLQLPPRPPGTQASMILLPGPPVDSTLHQSLETDTLLTKLCGQDRLLRQLQEDLDKRQEEKEQLEAALELTRQQLGQATREAAASGKAWGRQRLLQDRLVNVRAALCHLTQERERVWDTYSGLEQDLGTLRETLEYLLHLGSPQDRASAQQQLWMVEDTLAGLGGPQKQPPHTEPKSPSPAPQREESSERESLSESLELSSPQSPEVDWGQPPGGDRALSSSQSGVGSPRVSRASSPECRQQSSPLLRTKAPLARPRMSAQEQLERMRRNQACGLSLPRPTSPRLLTLGRTLSPVPRQPDMEQRPIVGAAKWLRSSGSWSSPRHSTTYSPVSGGHRERVLSLSQALATEASQWHRLMTASPERNLDTRGDCLQPSPQPPSEELPQVTSSPTSHKANSATTGFSCQGSGRGLAPWEPRWDPGKAPPALAQEEGAWPLRVTLLQSSF

Gene Information

Entrez Gene ID
Gene Name
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
Gene Symbol
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:UniProtKB-KW C cytoplasm
GO:0016020 IEA:UniProtKB-KW C membrane
GO:0008289 IEA:UniProtKB-KW F lipid binding

Domain Information

InterPro Annotations

Accession Description
IPR001849 Pleckstrin homology domain
IPR011993 Pleckstrin homology-like domain

UniProt Annotations

Entry Information

Gene Name
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
Protein Entry
PKHA4_RAT
UniProt ID
Species
Rat

Comments

Comment Type Description
Function Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides
Similarity Contains 1 PH domain. {ECO:0000255|PROSITE- ProRule:PRU00145}.
Subcellular Location Cytoplasm . Membrane {ECO:0000305}; Peripheral membrane protein .

Identical and Related Proteins

Unique RefSeq proteins for LMP013299 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
40018570 RefSeq NP_954532 779 pleckstrin homology domain-containing family A member 4

Identical Sequences to LMP013299 proteins

Reference Database Accession Length Protein Name
GI:40018570 GenBank AAH61738.1 779 Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 [Rattus norvegicus]
GI:40018570 SwissProt P60669.1 779 RecName: Full=Pleckstrin homology domain-containing family A member 4; Short=PH domain-containing family A member 4; AltName: Full=Phosphoinositol 3-phosphate-binding protein 1; Short=PEPP-1 [Rattus norvegicus]

Related Sequences to LMP013299 proteins

Reference Database Accession Length Protein Name
GI:40018570 GenBank AAH61738.1 779 Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 [Rattus norvegicus]
GI:40018570 GenBank EDM07333.1 751 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4, isoform CRA_a [Rattus norvegicus]
GI:40018570 RefSeq XP_006541225.1 779 PREDICTED: pleckstrin homology domain-containing family A member 4 isoform X5 [Mus musculus]
GI:40018570 SwissProt P60669.1 779 RecName: Full=Pleckstrin homology domain-containing family A member 4; Short=PH domain-containing family A member 4; AltName: Full=Phosphoinositol 3-phosphate-binding protein 1; Short=PEPP-1 [Rattus norvegicus]