Gene/Proteome Database (LMPD)

LMPD ID
LMP013326
Gene ID
310645
Species
Rattus norvegicus (Rat)
Gene Name
phosphomevalonate kinase
Gene Symbol
Pmvk
Alternate Names
phosphomevalonate kinase;
Chromosome
2
Map Location
2q34

Proteins

phosphomevalonate kinase
Refseq ID NP_001008353
Protein GI 56605780
UniProt ID Q5RK24
mRNA ID NM_001008352
Length 194
MAPLGASPRLVLLFSGKRKSGKDFVTERLQSRLGGNICAVLRLSGPLKEQYAREHGLDFQKLLDASTYKETYRRDMICWGEEKRQADPGFFCRKIVEGVSQPIWLVSDTRRMSDIQWFQEAYGALTQTVRVVASEQSRQQRGWVFTRGVDDAESECGLDSFGDFDWVIENHGDEQCLEDQLENLLEFIHAKLQR

Gene Information

Entrez Gene ID
310645
Gene Name
phosphomevalonate kinase
Gene Symbol
Pmvk
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 IEA:Ensembl C cytosol
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0016020 IEA:Ensembl C membrane
GO:0005777 IEA:Ensembl C peroxisome
GO:0005524 IEA:Ensembl F ATP binding
GO:0004631 IDA:RGD F phosphomevalonate kinase activity
GO:0006695 NAS:UniProtKB P cholesterol biosynthetic process
GO:0019287 IDA:RGD P isopentenyl diphosphate biosynthetic process, mevalonate pathway
GO:0008299 IDA:RGD P isoprenoid biosynthetic process
GO:0070723 IEA:Ensembl P response to cholesterol

KEGG Pathway Links

KEGG Pathway ID Description
M00095 C5 isoprenoid biosynthesis, mevalonate pathway
rno01100 Metabolic pathways
ko04146 Peroxisome
rno04146 Peroxisome
ko00900 Terpenoid backbone biosynthesis
rno00900 Terpenoid backbone biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
5954496 Activation of gene expression by SREBF (SREBP)
5953924 Cholesterol biosynthesis
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins
5954497 Regulation of cholesterol biosynthesis by SREBP (SREBF)

Domain Information

InterPro Annotations

Accession Description
IPR005919 Higher eukaryotic phosphomevalonate kinase
IPR027417 P-loop containing nucleoside triphosphate hydrolase

UniProt Annotations

Entry Information

Gene Name
phosphomevalonate kinase
Protein Entry
Q5RK24_RAT
UniProt ID
Q5RK24
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP013326 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
56605780 RefSeq NP_001008353 194 phosphomevalonate kinase

Identical Sequences to LMP013326 proteins

Reference Database Accession Length Protein Name
GI:56605780 GenBank AAH86349.1 194 Phosphomevalonate kinase [Rattus norvegicus]
GI:56605780 GenBank EDM00622.1 194 phosphomevalonate kinase, isoform CRA_c [Rattus norvegicus]

Related Sequences to LMP013326 proteins

Reference Database Accession Length Protein Name
GI:56605780 GenBank AAH86349.1 194 Phosphomevalonate kinase [Rattus norvegicus]
GI:56605780 GenBank EDL15192.1 192 phosphomevalonate kinase, isoform CRA_c [Mus musculus]
GI:56605780 GenBank EDM00622.1 194 phosphomevalonate kinase, isoform CRA_c [Rattus norvegicus]
GI:56605780 SwissProt Q9D1G2.3 192 RecName: Full=Phosphomevalonate kinase; Short=PMKase [Mus musculus]