Gene/Proteome Database (LMPD)

LMPD ID
LMP013332
Gene ID
310900
Species
Rattus norvegicus (Rat)
Gene Name
microsomal triglyceride transfer protein
Gene Symbol
Mttp
Synonyms
MTP;
Alternate Names
microsomal triglyceride transfer protein large subunit;
Chromosome
2
Map Location
2q44

Proteins

microsomal triglyceride transfer protein large subunit precursor
Refseq ID NP_001101197
Protein GI 157819691
UniProt ID D4A1W8
mRNA ID NM_001107727
Length 896
MILLAVLFLCFFSSYSASVKGHTTGLSLNNERLYKLTYSTEVFLDGGKGKLQDSVGYRISSDVDVVLLWRNPDGDDDQLIQVTITAVNVENAGQQRGEKSIFKGKSTPKIVGKDNLEALRRPMLLHLVRGKVKEFYSYENEPVGIENLKRGLASLFQMQLTSGTTNEVDISGDCKVTYQAQQDKVVKIKALDTCKIERSGFTTANQVLGVTSKATSVTTYKIEDSFVTAVVAEETRAFALNFLQTVAGKIVSKQKLELKTTEAGPRMVPGKQVAGVIKAIDSKYKAIPIVGQVLQSVCKGCPSLAEHWQSIRKHLEPENLSNAEAVQSFLAFIQHLRTSRREEILQILKAEKKEVLPQLVDAVTSAQTPASLEAILDFLDFKSDSSIILQERFLYACGFASHPDEELLQALLSKFKGSFASNDIRESVMIIIGALVRKLCQNEGCKLKAVVEAKKLILGGLEKPEKKEDTTMYLLALKNALLPEGIPLLLKYAEAGEGPVSHLATTVLQRYDASFITDEVKKTLNRIYHQNRKVHEKTVRTTAAAVILKNNPSYMDVKNILLSIGELPKEMNKYMLTIVQDILHFEMPASKMIRRVLKEMIVHNYDRFSKSGSSSAYTGYVERSPHAASTYSLDILYSGSGILRRSNLNIFQYIGKAELHGSQVVIEAQGLEGLIAATPDEGEENLDSYAGMSAILFDVQLRPVTFFNGYSDLMSKMLSASGDPVSVVKGLILLIDHSQDIQLQSGLKANMDIQGGLAIDISGSMEFSLWYRESKTRVKNRVAVVITSDITVDSSFVKAGLESRAETEAGLEFISTVQFSQYPFLVCMQMDKAEAPLRQFETKYERLSTGRGYVSRRRKESLVPGCELPLHQENSEMCNVVFPPQPESGNSGGGWF
sig_peptide: 1..21 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2297 peptide sequence: MILLAVLFLCFFSSYSASVKG

Gene Information

Entrez Gene ID
310900
Gene Name
microsomal triglyceride transfer protein
Gene Symbol
Mttp
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016323 IDA:RGD C basolateral plasma membrane
GO:0031526 IDA:RGD C brush border membrane
GO:0005794 IDA:RGD C Golgi apparatus
GO:0031988 IDA:RGD C membrane-bounded vesicle
GO:0031528 IDA:RGD C microvillus membrane
GO:0005791 IDA:RGD C rough endoplasmic reticulum
GO:0034185 IPI:RGD F apolipoprotein binding
GO:0005319 IDA:RGD F lipid transporter activity
GO:0046982 IPI:RGD F protein heterodimerization activity
GO:0042632 IEP:RGD P cholesterol homeostasis
GO:0006869 IDA:RGD P lipid transport
GO:0042157 IDA:RGD P lipoprotein metabolic process
GO:0042953 IEA:Ensembl P lipoprotein transport
GO:0006497 IEA:Ensembl P protein lipidation
GO:0051592 IEP:RGD P response to calcium ion
GO:0006641 IEA:Ensembl P triglyceride metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ko04975 Fat digestion and absorption
rno04975 Fat digestion and absorption

REACTOME Pathway Links

REACTOME Pathway ID Description
5953879 Chylomicron-mediated lipid transport
5953754 Lipid digestion, mobilization, and transport
5953836 Lipoprotein metabolism
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins

Domain Information

InterPro Annotations

Accession Description
IPR015819 Lipid transport protein, beta-sheet shell
IPR001747 Lipid transport protein, N-terminal
IPR015816 Vitellinogen, beta-sheet N-terminal
IPR011030 Vitellinogen, superhelical

UniProt Annotations

Entry Information

Gene Name
microsomal triglyceride transfer protein
Protein Entry
D4A1W8_RAT
UniProt ID
D4A1W8
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP013332 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
157819691 RefSeq NP_001101197 896 microsomal triglyceride transfer protein large subunit precursor

Identical Sequences to LMP013332 proteins

Reference Database Accession Length Protein Name
GI:157819691 GenBank EDL82305.1 896 microsomal triglyceride transfer protein [Rattus norvegicus]

Related Sequences to LMP013332 proteins

Reference Database Accession Length Protein Name
GI:157819691 DBBJ BAE27255.1 894 unnamed protein product [Mus musculus]
GI:157819691 GenBank AAH12686.1 894 Microsomal triglyceride transfer protein [Mus musculus]
GI:157819691 GenBank EDL12110.1 894 microsomal triglyceride transfer protein [Mus musculus]
GI:157819691 GenBank EDL82305.1 896 microsomal triglyceride transfer protein [Rattus norvegicus]