Gene/Proteome Database (LMPD)

LMPD ID
LMP013370
Gene ID
314180
Species
Rattus norvegicus (Rat)
Gene Name
MAM domain containing glycosylphosphatidylinositol anchor 2
Gene Symbol
Mdga2
Synonyms
Mamdc1;
Alternate Names
MAM domain-containing glycosylphosphatidylinositol anchor protein 2; MAM domain-containing protein 1;
Chromosome
6
Map Location
6q24

Proteins

MAM domain-containing glycosylphosphatidylinositol anchor protein 2 precursor
Refseq ID NP_954890
Protein GI 40538872
UniProt ID P60756
mRNA ID NM_199269
Length 949
MDLVYGLVWLLTVLLEGISGQGVYAPPTVRIVHSGLACNIEEERYSERVYTIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRITSIQRHQGGRYYCKAENGLGSPAIKSIRVDVYYLDDPVVTVHQSIGEAKEQFYYERTVFLRCVANSNPPVRYSWRRGQEVLLQGSDKGVEIYEPFFTQGETKILKLKNLRPQDYANYSCIASVRNVCNIPDKMVSFRLSNKTASPSIKLLVDDPIVVNPGEAITLVCVTTGGEPMPSLTWVRSFGTLPEKIVLNGGTLTIPAITSDDAGTYSCIANNNVGNPAKKSTNIIVRALKKGRFWITPDPYHKDDNIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPKPIILWSRADKEVAMPDGTMQMESYDGTLRIVNVSREMSGMYRCQTSQYNGFNVKPREALVQLIVQYPPAVEPAFLEIRQGQDRSVTMSCRVLRAYPIRVLTYEWRLGNKLLRTGQFDSQEYTEYPLKSLSNENYGVYNCSIINEAGAGRCSFLVTGKAYAPEFYYDTYNPVWQNRHRVYSYSLQWTQMNPDAVDRIVAYRLGIRQAGQQRWWEQEIKINGNIQKGELITYNLTELIKPEAYEVRLTPLTKFGEGDSTIRVIKYTGEFHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIETSRPRLEGEKARLLSPVFSIAPKNPYGPTNSAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENPLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAEGECAKQDLPTKNSVDGAVGILVHIWLFPVIILISILSPRR
sig_peptide: 1..25 inference: non-experimental evidence, no additional details recorded note: Potential; propagated from UniProtKB/Swiss-Prot (P60756.1) calculated_mol_wt: 2710 peptide sequence: MDLVYGLVWLLTVLLEGISGQGVYA mat_peptide: 26..924 product: MAM domain-containing glycosylphosphatidylinositol anchor protein 2 experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (P60756.1) calculated_mol_wt: 101262 peptide sequence: PPTVRIVHSGLACNIEEERYSERVYTIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRITSIQRHQGGRYYCKAENGLGSPAIKSIRVDVYYLDDPVVTVHQSIGEAKEQFYYERTVFLRCVANSNPPVRYSWRRGQEVLLQGSDKGVEIYEPFFTQGETKILKLKNLRPQDYANYSCIASVRNVCNIPDKMVSFRLSNKTASPSIKLLVDDPIVVNPGEAITLVCVTTGGEPMPSLTWVRSFGTLPEKIVLNGGTLTIPAITSDDAGTYSCIANNNVGNPAKKSTNIIVRALKKGRFWITPDPYHKDDNIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPKPIILWSRADKEVAMPDGTMQMESYDGTLRIVNVSREMSGMYRCQTSQYNGFNVKPREALVQLIVQYPPAVEPAFLEIRQGQDRSVTMSCRVLRAYPIRVLTYEWRLGNKLLRTGQFDSQEYTEYPLKSLSNENYGVYNCSIINEAGAGRCSFLVTGKAYAPEFYYDTYNPVWQNRHRVYSYSLQWTQMNPDAVDRIVAYRLGIRQAGQQRWWEQEIKINGNIQKGELITYNLTELIKPEAYEVRLTPLTKFGEGDSTIRVIKYTGEFHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIETSRPRLEGEKARLLSPVFSIAPKNPYGPTNSAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENPLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAEGECAKQDLPTKNSVD

Gene Information

Entrez Gene ID
314180
Gene Name
MAM domain containing glycosylphosphatidylinositol anchor 2
Gene Symbol
Mdga2
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0031225 IEA:UniProtKB-KW C anchored component of membrane
GO:0005886 IEA:UniProtKB-KW C plasma membrane
GO:0007389 IEA:Ensembl P pattern specification process
GO:0021522 IEP:HGNC P spinal cord motor neuron differentiation

Domain Information

InterPro Annotations

Accession Description
IPR013320 Concanavalin A-like lectin/glucanase domain
IPR003961 Fibronectin type III
IPR013098 Immunoglobulin I-set
IPR003599 Immunoglobulin subtype
IPR003598 Immunoglobulin subtype 2
IPR007110 Immunoglobulin-like domain
IPR013783 Immunoglobulin-like fold
IPR000998 MAM domain

UniProt Annotations

Entry Information

Gene Name
MAM domain containing glycosylphosphatidylinositol anchor 2
Protein Entry
MDGA2_RAT
UniProt ID
P60756
Species
Rat

Comments

Comment Type Description
Function May be involved in cell-cell interactions
Similarity Contains 1 MAM domain. {ECO:0000255|PROSITE- ProRule:PRU00128}.
Similarity Contains 1 fibronectin type-III domain
Similarity Contains 6 Ig-like (immunoglobulin-like) domains
Subcellular Location Cell membrane ; Lipid-anchor, GPI-anchor .
Subunit Interacts (through the Ig-like domains) with NLGN2
Tissue Specificity Expressed predominantly in neuronal tissue. Expressed in brain. {ECO:0000269|PubMed:15019943, ECO:0000269|PubMed:23248271}.

Identical and Related Proteins

Unique RefSeq proteins for LMP013370 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
40538872 RefSeq NP_954890 949 MAM domain-containing glycosylphosphatidylinositol anchor protein 2 precursor

Identical Sequences to LMP013370 proteins

Reference Database Accession Length Protein Name
GI:40538872 GenBank AAQ75750.1 949 MAM domain-containing glycosylphosphatidylinositol anchor 2 [Rattus norvegicus]
GI:40538872 SwissProt P60756.1 949 RecName: Full=MAM domain-containing glycosylphosphatidylinositol anchor protein 2; AltName: Full=MAM domain-containing protein 1; Flags: Precursor [Rattus norvegicus]

Related Sequences to LMP013370 proteins

Reference Database Accession Length Protein Name
GI:40538872 GenBank AAQ75750.1 949 MAM domain-containing glycosylphosphatidylinositol anchor 2 [Rattus norvegicus]
GI:40538872 RefSeq NP_996893.3 949 MAM domain-containing glycosylphosphatidylinositol anchor protein 2 isoform B precursor [Mus musculus]
GI:40538872 SwissProt P60756.1 949 RecName: Full=MAM domain-containing glycosylphosphatidylinositol anchor protein 2; AltName: Full=MAM domain-containing protein 1; Flags: Precursor [Rattus norvegicus]
GI:40538872 SwissProt P60755.1 949 RecName: Full=MAM domain-containing glycosylphosphatidylinositol anchor protein 2; AltName: Full=MAM domain-containing protein 1; Flags: Precursor [Mus musculus]