Gene/Proteome Database (LMPD)
LMPD ID
LMP013402
Gene ID
Species
Rattus norvegicus (Rat)
Gene Name
serum deprivation response
Gene Symbol
Alternate Names
serum deprivation-response protein; cavin-2; phosphatidylserine-binding protein; sdpr {ECO:0000312|EMBL:AAH81956.1}; serum deprivation response protein;
Chromosome
9
Map Location
9q22
Proteins
| serum deprivation-response protein | |
|---|---|
| Refseq ID | NP_001007713 |
| Protein GI | 56090257 |
| UniProt ID | Q66H98 |
| mRNA ID | NM_001007712 |
| Length | 417 |
| MGEDAAQAEKFQHPNTDMLQEKPSNPSPMPSSTPSPSLNLGSTEEAIRDNSQVNAVTVHTLLDKLVNMLDAVRENQHNMEQRQINLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSRKVSAHTRAVRERLEKQCVQVKRLENNHAQLLRRNHFKVLIFQEESEIPASVFVKEPVPSTAEGKELADENKSLEETLHNVDLSSDDELPGDEEALEDSAEEKMEESRAEKIKRSSLKKVDSLKKAFSRQNIEKKMNKLGTKIVSVERREKIKKSLTPNHQKASSGKSSPFKVSPLSFGRKKIREGESSAENETKLEEQVQDDHEEGSFTEGLSEASLPSGLLEGSAEDAEKSALRGNNSGVGSNADLTIEEDEEEESVALQQAQQVRYESGYMLNSKEMEESSEKHVQAAVLHVDQTA | |
Gene Information
Entrez Gene ID
Gene Name
serum deprivation response
Gene Symbol
Species
Rattus norvegicus
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005829 | ISS:UniProtKB | C | cytosol |
| GO:0016020 | IEA:UniProtKB-KW | C | membrane |
| GO:0001786 | ISS:UniProtKB | F | phosphatidylserine binding |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR026752 | Cavin family |
UniProt Annotations
Entry Information
Comments
| Comment Type | Description |
|---|---|
| Function | May play a role in targeting PRKCA to caveolae |
| Miscellaneous | Binds phosphatidylserine (PS) in a calcium- independent manner. PS-binding is inhibited by phosphotidic acid and phosphatidylinositol. Does not bind phosphatidylcholine (By similarity) |
| Ptm | Phosphorylated on Ser residues |
| Ptm | The N-terminus is blocked |
| Similarity | Belongs to the PTRF/SDPR family |
| Subcellular Location | Cytoplasm, cytosol . Membrane, caveola . Note=Colocalizes with CAV1 to caveolae. |
| Subunit | Interacts with MURC; this augments the transactivation of NPPA by MURC (By similarity). Binds to PRKCA in the presence of phosphatidylserine |
Identical and Related Proteins
Unique RefSeq proteins for LMP013402 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 56090257 | RefSeq | NP_001007713 | 417 | serum deprivation-response protein |
Identical Sequences to LMP013402 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:56090257 | GenBank | AAH81956.1 | 417 | Serum deprivation response [Rattus norvegicus] |
| GI:56090257 | GenBank | EDL99083.1 | 417 | serum deprivation response protein [Rattus norvegicus] |
| GI:56090257 | SwissProt | Q66H98.3 | 417 | RecName: Full=Serum deprivation-response protein; AltName: Full=Cavin-2; AltName: Full=Phosphatidylserine-binding protein [Rattus norvegicus] |
Related Sequences to LMP013402 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:56090257 | DBBJ | BAC39116.1 | 418 | unnamed protein product [Mus musculus] |
| GI:56090257 | GenBank | AAH81956.1 | 417 | Serum deprivation response [Rattus norvegicus] |
| GI:56090257 | GenBank | EDL99083.1 | 417 | serum deprivation response protein [Rattus norvegicus] |
| GI:56090257 | SwissProt | Q66H98.3 | 417 | RecName: Full=Serum deprivation-response protein; AltName: Full=Cavin-2; AltName: Full=Phosphatidylserine-binding protein [Rattus norvegicus] |