Gene/Proteome Database (LMPD)

LMPD ID
LMP013403
Gene ID
316400
Species
Rattus norvegicus (Rat)
Gene Name
post-GPI attachment to proteins 1
Gene Symbol
Pgap1
Alternate Names
GPI inositol-deacylase; GPI deacylase; Post GPI Attachment to Proteins 1; post-GPI attachment to proteins factor 1;
Chromosome
9
Map Location
9q31
EC Number
3.1.-.-

Proteins

GPI inositol-deacylase
Refseq ID NP_973719
Protein GI 42538976
UniProt ID Q765A7
mRNA ID NM_201990
Length 922
MFLHSVNLWNLAFYVFMVFLATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLTKRYPAYELYLYGEGSYAEEHKILPLTGIPVLFLPGNAGSYKQVRSIGSIALRKAEDIDFKYHFDFFSVNFNEELVALYGGSLQKQTKFVHECIKAILKLYKGQEFPPTSVAIIGHSMGGLVARALLTLKNFKQDLINLLVTQATPHVAPVMPLDRFITEFYMTVNNYWILNARHINLTTLSVAGGFRDYQVRSGLTFLPTLSHHTSALSVVTSAVPKTWVSTDHLSIVWCKQLQLTTIRAFFDLIDADTKQITQKSKKKLSVLNHHFIRHPAKQFEENPSIISDLTGTSMWVPVKVSRWSYVAYNESDKIYFAFPLANHRKVYTHAYCQSTMLDTNSWIFGCINSTSMCRQGVDLSWKAELLPTIKSLTLRLQDYPSLSHIVVYVPSVHGSKFVVDCEFFKKEARSIQLPVTHLFSFGLSSRKAIINTSGRYYNIELLNLGQIYQAFKVNVVSKCTGGKEEITSIYKLHIPWSYEDSLTIAQVPSSVDISLKLHVAQPENDSHVALLKMYTSSDCQYEVTIKTSFPQILGQVVRFHGGALPAYVVSSILLAYGGQLYSLLSTGFCLEYGTMLDKEAKPYKVDPFVIMIKFLLGYKWFKELWDAVLLPELDAIVLTSQSMCFPLVSLILFLFGTCTAYWSGLLSSASVQLLSSLWLALKRPAELPKDVKVMSPDLPVLTVVFLIISWTTCGALAILLSYLYYVFKVVHLQASLTTFKNNQPVNPKHSRRSEKKSNHHKDSAIQNPRLSANDAEDSLRMHSTVINLLTWVVLLSMPSLIYWSKNLRYYFKLNPDPCKPLAFLLIPAIAVLGNTHTVSIKSSKLLKTASQFPLPLAVGVIAFGSSHLYRVPCFVIIPLVFHSLCNFM

Gene Information

Entrez Gene ID
316400
Gene Name
post-GPI attachment to proteins 1
Gene Symbol
Pgap1
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IDA:UniProtKB C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0004518 IDA:UniProtKB F nuclease activity
GO:0042578 IDA:UniProtKB F phosphoric ester hydrolase activity
GO:0006506 IMP:RGD P GPI anchor biosynthetic process
GO:0009948 IEA:Ensembl P anterior/posterior axis specification
GO:0009880 IEA:Ensembl P embryonic pattern specification
GO:0021871 IEA:Ensembl P forebrain regionalization
GO:0060322 IEA:Ensembl P head development
GO:0006886 IEA:InterPro P intracellular protein transport
GO:0015798 IDA:UniProtKB P myo-inositol transport
GO:0090305 IDA:GOC P nucleic acid phosphodiester bond hydrolysis
GO:0007605 IEA:Ensembl P sensory perception of sound

KEGG Pathway Links

KEGG Pathway ID Description
ko00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
rno00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
rno01100 Metabolic pathways

REACTOME Pathway Links

REACTOME Pathway ID Description
5953740 Attachment of GPI anchor to uPAR
5953345 Metabolism of proteins
5953735 Post-translational modification: synthesis of GPI-anchored proteins
5953728 Post-translational protein modification

Domain Information

InterPro Annotations

Accession Description
IPR029058 Alpha/Beta hydrolase fold
IPR012908 GPI inositol-deacylase PGAP1-like

UniProt Annotations

Entry Information

Gene Name
post-GPI attachment to proteins 1
Protein Entry
PGAP1_RAT
UniProt ID
Q765A7
Species
Rat

Comments

Comment Type Description
Function Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi
Similarity Belongs to the GPI inositol-deacylase family
Subcellular Location Endoplasmic reticulum membrane ; Multi-pass membrane protein .

Identical and Related Proteins

Unique RefSeq proteins for LMP013403 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
42538976 RefSeq NP_973719 922 GPI inositol-deacylase

Identical Sequences to LMP013403 proteins

Reference Database Accession Length Protein Name
GI:42538976 DBBJ BAD08353.1 922 GPI deacylase [Rattus norvegicus]
GI:42538976 GenBank EDL99061.1 922 GPI deacylase [Rattus norvegicus]
GI:42538976 SwissProt Q765A7.1 922 RecName: Full=GPI inositol-deacylase; AltName: Full=Post-GPI attachment to proteins factor 1 [Rattus norvegicus]

Related Sequences to LMP013403 proteins

Reference Database Accession Length Protein Name
GI:42538976 DBBJ BAD08353.1 922 GPI deacylase [Rattus norvegicus]
GI:42538976 GenBank EDL99061.1 922 GPI deacylase [Rattus norvegicus]
GI:42538976 SwissProt Q765A7.1 922 RecName: Full=GPI inositol-deacylase; AltName: Full=Post-GPI attachment to proteins factor 1 [Rattus norvegicus]
GI:42538976 SwissProt Q3UUQ7.3 922 RecName: Full=GPI inositol-deacylase; AltName: Full=Post-GPI attachment to proteins factor 1 [Mus musculus]