Gene/Proteome Database (LMPD)
LMPD ID
LMP013413
Gene ID
Species
Rattus norvegicus (Rat)
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class U
Gene Symbol
Synonyms
sakura; Cdc91l1;
Alternate Names
phosphatidylinositol glycan anchor biosynthesis class U protein; protein CDC91-like 1; GPI transamidase component PIG-U; CDC91 cell division cycle 91-like 1; cell division cycle protein 91-like 1; liver regeneration-related protein LRRGT00059;
Chromosome
3
Map Location
3q42
Summary
subunit of GPI transamidase that attaches GPI-anchors to proteins [RGD, Feb 2006]
Orthologs
Proteins
| phosphatidylinositol glycan anchor biosynthesis class U protein precursor | |
|---|---|
| Refseq ID | NP_853668 |
| Protein GI | 31745144 |
| UniProt ID | Q8CHJ1 |
| mRNA ID | NM_181637 |
| Length | 435 |
| MAAPLALVLVVAVTVRAALFRSSLAEFISERVEVVSPLSSWKRVVEGLALLDLGVSPYSGAVFHETPLIIYLFHFLIDYAELVFMITDALTAIALYFAIQDFNKVVFKKQKLLLELDQYAPDVAELIRTPMEMRYIPLKVALFYLLNPYTILSCVAKSTCAINNTLIAFFILTTIKGSVFLSAIFLALATYQSLYPITLFAPGLLYLLQRQYIPVKVKSKAFWIFSWEYAMMYTGSLVVIVCLSFFLLSSWDFIPAVYGFILSVPDLTPNIGLFWYFFAEMFEHFSLFFVCVFQINVFFYTVPLAIKLKEHPIFFMFIQIAIISIFKSYPTVGDVALYMAFFPVWSHLYRFLRNIFVLTCIIIVCSLLFPVLWHLWIYAGSANSNFFYAITLTFNVGQILLISDYFYAFLRREYYLTHGLYLTAKDGTEAMLVLK | |
| sig_peptide: 1..17 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1694 peptide sequence: MAAPLALVLVVAVTVRA | |
Gene Information
Entrez Gene ID
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class U
Gene Symbol
Species
Rattus norvegicus
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0042765 | ISS:UniProtKB | C | GPI-anchor transamidase complex |
| GO:0006506 | IEA:UniProtKB-UniPathway | P | GPI anchor biosynthetic process |
KEGG Pathway Links
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR009600 | GPI transamidase subunit PIG-U |
UniProt Annotations
Entry Information
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class U
Protein Entry
PIGU_RAT
UniProt ID
Species
Rat
Comments
| Comment Type | Description |
|---|---|
| Alternative Products | Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8CHJ1-1; Sequence=Displayed; Name=2; IsoId=Q8CHJ1-2; Sequence=VSP_009544, VSP_009545; Note=No experimental confirmation available.; |
| Function | Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI |
| Pathway | Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis. |
| Sequence Caution | Sequence=AAQ96272.1; Type=Erroneous initiation; Evidence= ; |
| Similarity | Belongs to the PIGU family |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein . |
| Subunit | Forms a complex with PIGK/GPI8, PIGS, PIGT and GPAA1/GAA1 |
Identical and Related Proteins
Unique RefSeq proteins for LMP013413 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 31745144 | RefSeq | NP_853668 | 435 | phosphatidylinositol glycan anchor biosynthesis class U protein precursor |
Identical Sequences to LMP013413 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:31745144 | DBBJ | BAC53625.1 | 435 | PIG-U [Rattus norvegicus] |
| GI:31745144 | GenBank | EDL85923.1 | 435 | CDC91 cell division cycle 91-like 1 (S. cerevisiae), isoform CRA_a [Rattus norvegicus] |
| GI:31745144 | SwissProt | Q8CHJ1.3 | 435 | RecName: Full=Phosphatidylinositol glycan anchor biosynthesis class U protein; AltName: Full=Cell division cycle protein 91-like 1; Short=Protein CDC91-like 1; AltName: Full=GPI transamidase component PIG-U; AltName: Full=Liver regeneration-related protein LRRGT00059 [Rattus norvegicus] |
Related Sequences to LMP013413 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:31745144 | DBBJ | BAC53625.1 | 435 | PIG-U [Rattus norvegicus] |
| GI:31745144 | DBBJ | BAE25411.1 | 435 | unnamed protein product [Mus musculus] |
| GI:31745144 | GenBank | EDL85923.1 | 435 | CDC91 cell division cycle 91-like 1 (S. cerevisiae), isoform CRA_a [Rattus norvegicus] |
| GI:31745144 | SwissProt | Q8CHJ1.3 | 435 | RecName: Full=Phosphatidylinositol glycan anchor biosynthesis class U protein; AltName: Full=Cell division cycle protein 91-like 1; Short=Protein CDC91-like 1; AltName: Full=GPI transamidase component PIG-U; AltName: Full=Liver regeneration-related protein LRRGT00059 [Rattus norvegicus] |