Gene/Proteome Database (LMPD)

LMPD ID
LMP013429
Gene ID
361213
Species
Rattus norvegicus (Rat)
Gene Name
serine palmitoyltransferase, long chain base subunit 1
Gene Symbol
Sptlc1
Synonyms
Lcb1; Spt1; RGD1306617;
Alternate Names
serine palmitoyltransferase 1; serine-palmitoyl-CoA transferase 1; serine palmitoyltransferase subunit 1; long chain base biosynthesis protein 1;
Chromosome
17
Map Location
17p14

Proteins

serine palmitoyltransferase 1
Refseq ID NP_001101876
Protein GI 157822249
UniProt ID D4A2H2
mRNA ID NM_001108406
Length 473
MATVAEQWVLVEMVQALYEAPAYHLILEGILILWIIRLVFSKTYKLQERSDLTAKEKEELIEEWQPEPLVPPVSRNHPALNYNIVSGPPTHNIVVNGKECVNFASFNFLGLLANPRVKAAAFASLKKYGVGTCGPRGFYGTFDVHLDLEERLAKFMKTEEAIIYSYGFSTIASAIPAYSKRGDIVFVDSAACFAIQKGLQASRSDIKLFKHNDVADLERLLKEQEIEDQKNPRKARVTRRFIVAEGLYMNTGTICPLPELVRLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGISIDDIDLISANMENALASVGGFCCGRSFVVDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKKKCQTIHKSLQGVSGLKVVGESLCPALHLQLEESTGSRERDMKLLQEIVEQCMNKGIALTQARYLDKEEKCLPPPSIRVVVTVEQTDEELQRAAATIREAAQAVLL

Gene Information

Entrez Gene ID
361213
Gene Name
serine palmitoyltransferase, long chain base subunit 1
Gene Symbol
Sptlc1
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0035339 IEA:Ensembl C SPOTS complex
GO:0030170 IEA:InterPro F pyridoxal phosphate binding
GO:0004758 IEA:Ensembl F serine C-palmitoyltransferase activity
GO:0046513 IEA:Ensembl P ceramide biosynthetic process
GO:0046511 IEA:Ensembl P sphinganine biosynthetic process
GO:0006686 IEA:Ensembl P sphingomyelin biosynthetic process
GO:0046512 IEA:Ensembl P sphingosine biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
M00094 Ceramide biosynthesis
rno01100 Metabolic pathways
ko00600 Sphingolipid metabolism
rno00600 Sphingolipid metabolism
M00099 Sphingosine biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins
5954266 Sphingolipid de novo biosynthesis
5954267 Sphingolipid metabolism

Domain Information

InterPro Annotations

Accession Description
IPR004839 Aminotransferase, class I/classII
IPR015424 Pyridoxal phosphate-dependent transferase
IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1
IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2

UniProt Annotations

Entry Information

Gene Name
serine palmitoyltransferase, long chain base subunit 1
Protein Entry
D4A2H2_RAT
UniProt ID
D4A2H2
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP013429 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
157822249 RefSeq NP_001101876 473 serine palmitoyltransferase 1

Identical Sequences to LMP013429 proteins

Reference Database Accession Length Protein Name
GI:157822249 GenBank EDL98057.1 473 serine palmitoyltransferase, long chain base subunit 1 (predicted), isoform CRA_a [Rattus norvegicus]

Related Sequences to LMP013429 proteins

Reference Database Accession Length Protein Name
GI:157822249 DBBJ BAC40709.1 473 unnamed protein product [Mus musculus]
GI:157822249 EMBL CAA64897.1 473 serine C-palmitoyltransferase [Mus musculus]
GI:157822249 GenBank EDL41121.1 476 serine palmitoyltransferase, long chain base subunit 1, partial [Mus musculus]
GI:157822249 GenBank EDL98057.1 473 serine palmitoyltransferase, long chain base subunit 1 (predicted), isoform CRA_a [Rattus norvegicus]