Gene/Proteome Database (LMPD)
LMPD ID
LMP013481
Gene ID
Species
Rattus norvegicus (Rat)
Gene Name
zinc finger, DHHC-type containing 18
Gene Symbol
Alternate Names
palmitoyltransferase ZDHHC18; DHHC-18; zinc finger, DHHC domain containing 18; zinc finger DHHC domain-containing protein 18; membrane-associated DHHC18 zinc finger protein;
Chromosome
5
Map Location
5q36
EC Number
2.3.1.225
Proteins
| palmitoyltransferase ZDHHC18 | |
|---|---|
| Refseq ID | NP_001034428 |
| Protein GI | 86129586 |
| UniProt ID | Q2TGJ1 |
| mRNA ID | NM_001039339 |
| Length | 386 |
| MKDCEYQQISPGAAPPPASPGVHRPGPAAPPGPSPGPAPGAPRWSVSGSGSGSGSGSGSLGRRPRRKWEVFPGRNRFYCGGRLMLAGHGGVFALTLLLILSTTILFFIFDCPYLARTLTLAIPIIAAILFFFVMSCLLQTSFTDPGILPRATICEAAALEKQIDNTGSSTYRPPPRTREVMINGQMVKLKYCFTCKMFRPPRTSHCSVCDNCVERFDHHCPWVGNCVGRRNYRFFYAFILSLSFLTAFIFACVVTHLTLLSQGSNFLSALNKTPAGVLELVICFFSIWSILGLSGFHTYLVASNLTTNEDIKGSWSSKRGGEASVNPYSHKSIITNCCAVLCGPLPPSLIDRRGFVQSDTVLPSPIRSDEPACGAKPDASMVGGHP | |
Gene Information
Entrez Gene ID
Gene Name
zinc finger, DHHC-type containing 18
Gene Symbol
Species
Rattus norvegicus
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
| GO:0019706 | IEA:UniProtKB-EC | F | protein-cysteine S-palmitoyltransferase activity |
| GO:0008270 | IEA:InterPro | F | zinc ion binding |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR001594 | Zinc finger, DHHC-type, palmitoyltransferase |
UniProt Annotations
Entry Information
Gene Name
zinc finger, DHHC-type containing 18
Protein Entry
ZDH18_RAT
UniProt ID
Species
Rat
Comments
| Comment Type | Description |
|---|---|
| Catalytic Activity | Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA. |
| Domain | The DHHC domain is required for palmitoyltransferase activity |
| Function | Has palmitoyltransferase activity towards HRAS and LCK |
| Similarity | Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily |
| Similarity | Contains 1 DHHC-type zinc finger |
| Subcellular Location | Membrane ; Multi-pass membrane protein . |
Identical and Related Proteins
Unique RefSeq proteins for LMP013481 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 86129586 | RefSeq | NP_001034428 | 386 | palmitoyltransferase ZDHHC18 |
Identical Sequences to LMP013481 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:86129586 | GenBank | AAX73396.1 | 386 | membrane-associated DHHC18 zinc finger protein [Rattus norvegicus] |
| GI:86129586 | SwissProt | Q2TGJ1.1 | 386 | RecName: Full=Palmitoyltransferase ZDHHC18; AltName: Full=Zinc finger DHHC domain-containing protein 18; Short=DHHC-18 [Rattus norvegicus] |
Related Sequences to LMP013481 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:86129586 | GenBank | AAX73396.1 | 386 | membrane-associated DHHC18 zinc finger protein [Rattus norvegicus] |
| GI:86129586 | GenBank | AAI67166.1 | 380 | Zinc finger, DHHC domain containing 18 [synthetic construct] |
| GI:86129586 | RefSeq | NP_001017968.2 | 380 | palmitoyltransferase ZDHHC18 [Mus musculus] |
| GI:86129586 | SwissProt | Q2TGJ1.1 | 386 | RecName: Full=Palmitoyltransferase ZDHHC18; AltName: Full=Zinc finger DHHC domain-containing protein 18; Short=DHHC-18 [Rattus norvegicus] |