Gene/Proteome Database (LMPD)

LMPD ID
LMP013485
Gene ID
362732
Species
Rattus norvegicus (Rat)
Gene Name
alkylglycerol monooxygenase
Gene Symbol
Agmo
Synonyms
Tmem195; RGD1312038;
Alternate Names
alkylglycerol monooxygenase; transmembrane protein 195;
Chromosome
6
Map Location
6q21
EC Number
1.14.16.5

Proteins

alkylglycerol monooxygenase
Refseq ID NP_001129371
Protein GI 209571479
UniProt ID A0JPQ8
mRNA ID NM_001135899
Length 447
MRNPGAQDNVSVSQGMRAMFYMMKPSETAFQTVEEVPDYVKKATPFFIFLILLELVVSWILKGKPSGRLDDILTSMSAGVVSRLPNLFFRSLEVTSYIYIWENYRVCELPWDSPWTWYLTFLGVDFGYYWFHRMAHEINIIWAAHQAHHSSEDYNLSTALRQSVLQQYSSWVFYCPLALFVPPSVFAVHIQFNLLYQFWIHTEVIRTLGPLELVLNTPSHHRVHHGRNRYCIDKNYAGTLIIWDRIFGTFEAENEQVIYGLTHPIGTFEPFKVQFHHLLYIWTTFWATPGFCHKFSVLFKGPGWGPGKPRLGLSEEIPEVTGQEVPFTSSASQFLKIYAVLQFAVMLVFYEETFANTAVLSQVTILLRICFIILTLTSIGFLLDQRPKAAIVETLRCLLFLTLYRFGHLKPLIESLSFAFEIFFSVCIAFWGVRSITHLASGSWKKP

Gene Information

Entrez Gene ID
362732
Gene Name
alkylglycerol monooxygenase
Gene Symbol
Agmo
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 ISS:UniProtKB C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0050479 ISS:UniProtKB F glyceryl-ether monooxygenase activity
GO:0005506 ISS:UniProtKB F iron ion binding
GO:0046485 ISS:UniProtKB P ether lipid metabolic process
GO:0006633 IEA:InterPro P fatty acid biosynthetic process
GO:0006643 ISS:UniProtKB P membrane lipid metabolic process

Domain Information

InterPro Annotations

Accession Description
IPR006694 Fatty_acid_hydroxylase

UniProt Annotations

Entry Information

Gene Name
alkylglycerol monooxygenase
Protein Entry
ALKMO_RAT
UniProt ID
A0JPQ8
Species
Rat

Comments

Comment Type Description
Catalytic Activity 1-alkyl-sn-glycerol + tetrahydrobiopterin + O(2) = 1-O-alkyl-sn-glycerol + dihydrobiopterin + H(2)O.
Cofactor Name=Fe cation; Xref=ChEBI:CHEBI:24875; Evidence= ;
Function Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids. Ether lipids are essential components of brain membranes (By similarity)
Similarity Belongs to the sterol desaturase family. TMEM195 subfamily
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein .

Identical and Related Proteins

Unique RefSeq proteins for LMP013485 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
209571479 RefSeq NP_001129371 447 alkylglycerol monooxygenase

Identical Sequences to LMP013485 proteins

Reference Database Accession Length Protein Name
GI:209571479 GenBank AAI27546.1 447 Tmem195 protein [Rattus norvegicus]
GI:209571479 SwissProt A0JPQ8.1 447 RecName: Full=Alkylglycerol monooxygenase; AltName: Full=Transmembrane protein 195 [Rattus norvegicus]

Related Sequences to LMP013485 proteins

Reference Database Accession Length Protein Name
GI:209571479 GenBank AAI27546.1 447 Tmem195 protein [Rattus norvegicus]
GI:209571479 RefSeq NP_848882.2 447 alkylglycerol monooxygenase [Mus musculus]
GI:209571479 SwissProt Q8BS35.1 447 RecName: Full=Alkylglycerol monooxygenase; AltName: Full=Transmembrane protein 195 [Mus musculus]
GI:209571479 SwissProt A0JPQ8.1 447 RecName: Full=Alkylglycerol monooxygenase; AltName: Full=Transmembrane protein 195 [Rattus norvegicus]