Gene/Proteome Database (LMPD)
Proteins
| cholesterol 24-hydroxylase | |
|---|---|
| Refseq ID | NP_001102193 |
| Protein GI | 157817887 |
| UniProt ID | F7EN52 |
| mRNA ID | NM_001108723 |
| Length | 403 |
| MSTKYNKDSKMYRAIQTVFGERLFGQGLVSECDYGRWYKQRRVMDLAFSRSSLVSLMGTFNEKAEQLMEILEAKADGQTPVSMQDMLTCATIDILAKAAFGMETSMLLGAQKPLSQAVKVMLEGISASRNTLAKFMPGKRKQLREIRESIRLLRQVGKDWVQRRREALKRGEDVPADILTQILKAEEGAQDDEVLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRHLDYEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVPGQRFGLQEQATLKPLDPVLCTLRPRGWQPAPPPPPC | |
Gene Information
Entrez Gene ID
Gene Name
cytochrome P450, family 46, subfamily a, polypeptide 1
Gene Symbol
Species
Rattus norvegicus
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0033781 | IEA:Ensembl | F | cholesterol 24-hydroxylase activity |
| GO:0020037 | IEA:InterPro | F | heme binding |
| GO:0005506 | IEA:InterPro | F | iron ion binding |
| GO:0006707 | IEA:Ensembl | P | cholesterol catabolic process |
| GO:0006805 | IEA:Ensembl | P | xenobiotic metabolic process |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| ko00120 | Primary bile acid biosynthesis |
| rno00120 | Primary bile acid biosynthesis |
REACTOME Pathway Links
| REACTOME Pathway ID | Description |
|---|---|
| 5953720 | Bile acid and bile salt metabolism |
| 5953258 | Biological oxidations |
| 5953485 | Cytochrome P450 - arranged by substrate type |
| 5953932 | Endogenous sterols |
| 5953250 | Metabolism |
| 5953289 | Metabolism of lipids and lipoproteins |
| 5953326 | Phase 1 - Functionalization of compounds |
| 5953930 | Synthesis of bile acids and bile salts |
| 5953933 | Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
Domain Information
UniProt Annotations
Entry Information
Gene Name
cytochrome P450, family 46, subfamily a, polypeptide 1
Protein Entry
F7EN52_RAT
UniProt ID
Species
Rat
Identical and Related Proteins
Unique RefSeq proteins for LMP013489 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 157817887 | RefSeq | NP_001102193 | 403 | cholesterol 24-hydroxylase |
Identical Sequences to LMP013489 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:157817887 | GenBank | EDL97571.1 | 403 | cytochrome P450, family 46, subfamily a, polypeptide 1 (predicted) [Rattus norvegicus] |
Related Sequences to LMP013489 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:157817887 | GenBank | EDL97571.1 | 403 | cytochrome P450, family 46, subfamily a, polypeptide 1 (predicted) [Rattus norvegicus] |
| GI:157817887 | GenBank | AAI62019.1 | 500 | Cyp46a1 protein [Rattus norvegicus] |
| GI:157817887 | RefSeq | XP_006240610.1 | 500 | PREDICTED: cholesterol 24-hydroxylase isoform X1 [Rattus norvegicus] |
| GI:157817887 | RefSeq | XP_006971754.1 | 500 | PREDICTED: cholesterol 24-hydroxylase-like [Peromyscus maniculatus bairdii] |