Gene/Proteome Database (LMPD)

LMPD ID
LMP013492
Gene ID
362866
Species
Rattus norvegicus (Rat)
Gene Name
choline phosphotransferase 1
Gene Symbol
Chpt1
Alternate Names
cholinephosphotransferase 1; cholinephosphotransferase 1 alpha; diacylglycerol cholinephosphotransferase 1;
Chromosome
7
Map Location
7q13
EC Number
2.7.8.2

Proteins

cholinephosphotransferase 1
Refseq ID NP_001007751
Protein GI 56090323
UniProt ID Q66H21
mRNA ID NM_001007750
Length 398
MAAGAGARPAPRWVKALGEPLSAAQLRRLEDHRYSAAGESLFEPPLQLFWTWLLQWIPLWIAPNTITLFGLAINLFTTLVLIFYCPTVTEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLSTVFMAIGASIAVRLGTHPDWLFFCSFVGMFMFYCAHWQTYVSGVLRFGRVDVTEIQVALVIVFLLSTFGGAMMWDYTIPILEIKLKILPVLGVVGGLIFSCSNYFHVILHGGVGKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATNVFEKHPCLYTLMFGCVFAKVAQKLVIAHMTKSELYLQDTVFIGPGLLFLDQYFNNFIDEYVVLWIAMVITSFDMMIYFSSLCLQISRHLHLSIFKTSYQQAPEQVHKHID

Gene Information

Entrez Gene ID
362866
Gene Name
choline phosphotransferase 1
Gene Symbol
Chpt1
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:UniProtKB-KW C Golgi apparatus
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0004142 IEA:UniProtKB-EC F diacylglycerol cholinephosphotransferase activity
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0006663 IEA:Ensembl P platelet activating factor biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ko00565 Ether lipid metabolism
rno00565 Ether lipid metabolism
ko00564 Glycerophospholipid metabolism
rno00564 Glycerophospholipid metabolism
rno01100 Metabolic pathways
M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC

REACTOME Pathway Links

REACTOME Pathway ID Description
5953473 Glycerophospholipid biosynthesis
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins
5953474 Phospholipid metabolism
5954091 Synthesis of PC

Domain Information

InterPro Annotations

Accession Description
IPR000462 CDP-alcohol phosphatidyltransferase
IPR014472 Choline/ethanolamine phosphotransferase

UniProt Annotations

Entry Information

Gene Name
choline phosphotransferase 1
Protein Entry
CHPT1_RAT
UniProt ID
Q66H21
Species
Rat

Comments

Comment Type Description
Catalytic Activity CDP-choline + 1,2-diacyl-sn-glycerol = CMP + a phosphatidylcholine.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence= ; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence= ;
Function Catalyzes phosphatidylcholine biosynthesis from CDP- choline. It thereby plays a central role in the formation and maintenance of vesicular membranes (By similarity)
Pathway Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 2/2.
Similarity Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Subcellular Location Golgi apparatus membrane ; Multi-pass membrane protein .

Identical and Related Proteins

Unique RefSeq proteins for LMP013492 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
56090323 RefSeq NP_001007751 398 cholinephosphotransferase 1

Identical Sequences to LMP013492 proteins

Reference Database Accession Length Protein Name
GI:56090323 GenBank AAH82074.1 398 Choline phosphotransferase 1 [Rattus norvegicus]
GI:56090323 SwissProt Q66H21.1 398 RecName: Full=Cholinephosphotransferase 1; AltName: Full=Diacylglycerol cholinephosphotransferase 1 [Rattus norvegicus]

Related Sequences to LMP013492 proteins

Reference Database Accession Length Protein Name
GI:56090323 GenBank AAH82074.1 398 Choline phosphotransferase 1 [Rattus norvegicus]
GI:56090323 RefSeq XP_006241290.1 509 PREDICTED: cholinephosphotransferase 1 isoform X1 [Rattus norvegicus]
GI:56090323 RefSeq XP_006241293.1 406 PREDICTED: cholinephosphotransferase 1 isoform X4 [Rattus norvegicus]
GI:56090323 SwissProt Q66H21.1 398 RecName: Full=Cholinephosphotransferase 1; AltName: Full=Diacylglycerol cholinephosphotransferase 1 [Rattus norvegicus]