Gene/Proteome Database (LMPD)

LMPD ID
LMP013528
Gene ID
365619
Species
Rattus norvegicus (Rat)
Gene Name
arylsulfatase family, member K
Gene Symbol
Arsk
Synonyms
RGD1310182;
Alternate Names
arylsulfatase K; ASK;
Chromosome
2
Map Location
2q11
EC Number
3.1.6.-

Proteins

arylsulfatase K precursor
Refseq ID NP_001041382
Protein GI 114145523
UniProt ID Q32KJ2
mRNA ID NM_001047917
Length 563
MLLLLVSVIVALALVAPAPETQEKRLQVAQAPNVVLVASDSFDGRLTFQPGSQVVKLPFINFMRARGTTFLNAYTNSPICCPSRAAMWSGLFTHLTESWNNFKGLDPNYTTWMDVMEKHGYQTQKFGKLDYSSGHHSISNRVEAWTRDVAFLLRQEGRPIINLIPDKNRRRVMDKDWQNTDKAIAWLRQVNSTKPFVLYLGLNLPHPYPSPSSGENFGSSTFHTSLYWLEKVAYDAIKIPKWLALSEMHPVDYYSSYTKNCTGKFTENEIKNIRAFYYAMCAETDAMLGEIILALHKLNLLQKTIVIYTSDHGEMAMEHRQFYKMSMYEASAHVPILMMGPGIKANLQVPSLVSLVDIYPTMLDIAGIPLPLNLSGYSLLPLSSNTSANDQAFRVHHPPWILSEFHGCNANASTYMLRTGQWKYIAYSDGTLVQPQLFDLSLDPDELTNIATEFPEITYSLDQQLRSVINYPKVSASVHRYNKEQFIMWKQSVAQNYSNYIAHLRWHQDWQKDPRKYENAIQRWLAIHSSPPTHSPLSLVHQWLTTHSSPIAVDNKKTFSSYT
sig_peptide: 1..17 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1735 peptide sequence: MLLLLVSVIVALALVAP mat_peptide: 18..563 product: Arylsulfatase K experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q32KJ2.1) calculated_mol_wt: 62556 peptide sequence: APETQEKRLQVAQAPNVVLVASDSFDGRLTFQPGSQVVKLPFINFMRARGTTFLNAYTNSPICCPSRAAMWSGLFTHLTESWNNFKGLDPNYTTWMDVMEKHGYQTQKFGKLDYSSGHHSISNRVEAWTRDVAFLLRQEGRPIINLIPDKNRRRVMDKDWQNTDKAIAWLRQVNSTKPFVLYLGLNLPHPYPSPSSGENFGSSTFHTSLYWLEKVAYDAIKIPKWLALSEMHPVDYYSSYTKNCTGKFTENEIKNIRAFYYAMCAETDAMLGEIILALHKLNLLQKTIVIYTSDHGEMAMEHRQFYKMSMYEASAHVPILMMGPGIKANLQVPSLVSLVDIYPTMLDIAGIPLPLNLSGYSLLPLSSNTSANDQAFRVHHPPWILSEFHGCNANASTYMLRTGQWKYIAYSDGTLVQPQLFDLSLDPDELTNIATEFPEITYSLDQQLRSVINYPKVSASVHRYNKEQFIMWKQSVAQNYSNYIAHLRWHQDWQKDPRKYENAIQRWLAIHSSPPTHSPLSLVHQWLTTHSSPIAVDNKKTFSSYT

Gene Information

Entrez Gene ID
365619
Gene Name
arylsulfatase family, member K
Gene Symbol
Arsk
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005576 IEA:UniProtKB-KW C extracellular region
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0008484 IEA:InterPro F sulfuric ester hydrolase activity

REACTOME Pathway Links

REACTOME Pathway ID Description
5954485 Glycosphingolipid metabolism
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins
5953345 Metabolism of proteins
5953727 PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
5953728 Post-translational protein modification
5954267 Sphingolipid metabolism
5954489 The activation of arylsulfatases

Domain Information

InterPro Annotations

Accession Description
IPR017849 Alkaline phosphatase-like, alpha/beta/alpha
IPR017850 Alkaline-phosphatase-like, core domain
IPR000917 Sulfatase

UniProt Annotations

Entry Information

Gene Name
arylsulfatase family, member K
Protein Entry
ARSK_RAT
UniProt ID
Q32KJ2
Species
Rat

Comments

Comment Type Description
Cofactor Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence= ; Note=Binds 1 Ca(2+) ion per subunit. ;
Ptm The conversion to 3-oxoalanine (also known as C- formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity
Similarity Belongs to the sulfatase family
Subcellular Location Secreted .

Identical and Related Proteins

Unique RefSeq proteins for LMP013528 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
114145523 RefSeq NP_001041382 563 arylsulfatase K precursor

Identical Sequences to LMP013528 proteins

Reference Database Accession Length Protein Name
GI:114145523 SwissProt Q32KJ2.1 563 RecName: Full=Arylsulfatase K; Short=ASK; Flags: Precursor [Rattus norvegicus]
GI:114145523 tpe CAI84991.1 563 TPA: arylsulfatase K [Rattus norvegicus]

Related Sequences to LMP013528 proteins

Reference Database Accession Length Protein Name
GI:114145523 DBBJ BAB28703.1 563 unnamed protein product [Mus musculus]
GI:114145523 GenBank EDL37115.1 559 arylsulfatase K [Mus musculus]
GI:114145523 SwissProt Q32KJ2.1 563 RecName: Full=Arylsulfatase K; Short=ASK; Flags: Precursor [Rattus norvegicus]
GI:114145523 tpe CAI84991.1 563 TPA: arylsulfatase K [Rattus norvegicus]