Gene/Proteome Database (LMPD)
LMPD ID
LMP013547
Gene ID
Species
Rattus norvegicus (Rat)
Gene Name
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
Gene Symbol
Alternate Names
5'-AMP-activated protein kinase subunit gamma-2; AMPK gamma 2; AMP-activated protein kinase gamma2 subunit; adenosine monophosphate-activated protein kinase gamma 2-subunit;
Chromosome
4
Map Location
4q11
Summary
predicted to act as a non-catalytic subunit of an AMP-activated protein kinase [RGD, Feb 2006]
Orthologs
Proteins
| 5'-AMP-activated protein kinase subunit gamma-2 | |
|---|---|
| Refseq ID | NP_908940 |
| Protein GI | 34576559 |
| UniProt ID | Q6V7V4 |
| mRNA ID | NM_184051 |
| Length | 326 |
| MLEKLEFQEEEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYHNIAFIHPNTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCSKLETLETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETETE | |
Gene Information
Entrez Gene ID
Gene Name
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
Gene Symbol
Species
Rattus norvegicus
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0031588 | IDA:RGD | C | AMP-activated protein kinase complex |
| GO:0005615 | IEA:Ensembl | C | extracellular space |
| GO:0043531 | IEA:Ensembl | F | ADP binding |
| GO:0016208 | IDA:RGD | F | AMP binding |
| GO:0005524 | IEA:Ensembl | F | ATP binding |
| GO:0004862 | IEA:Ensembl | F | cAMP-dependent protein kinase inhibitor activity |
| GO:0008603 | IEA:Ensembl | F | cAMP-dependent protein kinase regulator activity |
| GO:0016301 | IEA:UniProtKB-KW | F | kinase activity |
| GO:0008607 | IEA:Ensembl | F | phosphorylase kinase regulator activity |
| GO:0030295 | IEA:Ensembl | F | protein kinase activator activity |
| GO:0019901 | IPI:RGD | F | protein kinase binding |
| GO:0005977 | IEA:Ensembl | P | glycogen metabolic process |
| GO:0035556 | IEA:Ensembl | P | intracellular signal transduction |
| GO:0010800 | IEA:Ensembl | P | positive regulation of peptidyl-threonine phosphorylation |
| GO:0006468 | IDA:GOC | P | protein phosphorylation |
| GO:0050790 | IDA:RGD | P | regulation of catalytic activity |
| GO:0019217 | IEA:Ensembl | P | regulation of fatty acid metabolic process |
| GO:0006110 | IEA:Ensembl | P | regulation of glycolytic process |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| ko04152 | AMPK signaling pathway |
| rno04152 | AMPK signaling pathway |
| ko04920 | Adipocytokine signaling pathway |
| rno04920 | Adipocytokine signaling pathway |
| ko04710 | Circadian rhythm |
| rno04710 | Circadian rhythm |
| rno04068 | FoxO signaling pathway |
| ko05410 | Hypertrophic cardiomyopathy (HCM) |
| rno05410 | Hypertrophic cardiomyopathy (HCM) |
| ko04910 | Insulin signaling pathway |
| rno04910 | Insulin signaling pathway |
| ko04932 | Non-alcoholic fatty liver disease (NAFLD) |
| rno04932 | Non-alcoholic fatty liver disease (NAFLD) |
| ko04921 | Oxytocin signaling pathway |
| rno04921 | Oxytocin signaling pathway |
REACTOME Pathway Links
| REACTOME Pathway ID | Description |
|---|---|
| 5953759 | AMPK inhibits chREBP transcriptional activation activity |
| 5954481 | Activation of PPARGC1A (PGC-1alpha) by phosphorylation |
| 5954019 | Energy dependent regulation of mTOR by LKB1-AMPK |
| 5953288 | Fatty acid, triacylglycerol, and ketone body metabolism |
| 5953430 | IGF1R signaling cascade |
| 5953428 | IRS-mediated signalling |
| 5953425 | IRS-related events |
| 5953429 | IRS-related events triggered by IGF1R |
| 5953467 | Import of palmitoyl-CoA into the mitochondrial matrix |
| 5953422 | Insulin receptor signalling cascade |
| 5953611 | Integration of energy metabolism |
| 5953916 | Membrane Trafficking |
| 5953250 | Metabolism |
| 5953289 | Metabolism of lipids and lipoproteins |
| 5953600 | Mitochondrial biogenesis |
| 5953601 | Organelle biogenesis and maintenance |
| 5953432 | PI3K Cascade |
| 5953733 | PKB-mediated events |
| 5954018 | Regulation of AMPK activity via LKB1 |
| 5954161 | Regulation of Rheb GTPase activity by AMPK |
| 5953381 | Signal Transduction |
| 5953423 | Signaling by Insulin receptor |
| 5953431 | Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) |
| 5954455 | Translocation of GLUT4 to the plasma membrane |
| 5953766 | mTOR signalling |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR000644 | CBS domain |
UniProt Annotations
Entry Information
Gene Name
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
Protein Entry
Q6V7V4_RAT
UniProt ID
Species
Rat
Identical and Related Proteins
Unique RefSeq proteins for LMP013547 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 34576559 | RefSeq | NP_908940 | 326 | 5'-AMP-activated protein kinase subunit gamma-2 |
Identical Sequences to LMP013547 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:34576559 | GenBank | AAQ55225.1 | 326 | AMP-activated protein kinase gamma 2 non-catalytic subunit [Rattus norvegicus] |
Related Sequences to LMP013547 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:34576559 | GenBank | AAQ55225.1 | 326 | AMP-activated protein kinase gamma 2 non-catalytic subunit [Rattus norvegicus] |
| GI:34576559 | GenBank | AAH97267.1 | 448 | Prkag2 protein, partial [Rattus norvegicus] |
| GI:34576559 | RefSeq | NP_663376.2 | 566 | 5'-AMP-activated protein kinase subunit gamma-2 isoform 1 [Mus musculus] |
| GI:34576559 | RefSeq | XP_006236014.1 | 566 | PREDICTED: 5'-AMP-activated protein kinase subunit gamma-2 isoform X4 [Rattus norvegicus] |