Gene/Proteome Database (LMPD)

LMPD ID
LMP013548
Gene ID
378774
Species
Rattus norvegicus (Rat)
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class W
Gene Symbol
Pigw
Alternate Names
phosphatidylinositol-glycan biosynthesis class W protein; PIG-W; phosphatidylinositol glycan, class W;
Chromosome
10
Map Location
10q26
EC Number
2.3.-.-;
Summary
inositol acetyltransferase enzyme [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Pigw

Proteins

phosphatidylinositol-glycan biosynthesis class W protein
Refseq ID NP_919443
Protein GI 37360979
UniProt ID Q7TSN4
mRNA ID NM_194461
Length 502
MSQKQLKEAFVSNLSGTSVLEVTQGLCFPAFCILCRGLLIIFSQHLCSFLHTWTTQFFMDFVVLIVPLVITLTVLSSFILLENLTVILCGAWLLYQIYHRRTCYAKVPVQKVFASFLKISLESEYNPAITCYRVINSVFTAIAILAVDFPLFPRRFAKTELYGTGAMDFGVGGFIFGAAMVCPEVRRKYTEGSRFNHLRKSLYSVWPLVFLGMGRLVIIKSIGYQEHSTEYGVHWNFFFTIIVVKLITSLLLIIFPLNKSWIVAISITVLYQLALDFTPLKGIILYGTDGRGTRVGLLNANREGIISTLGYVAIYMAGVQTGFYVFKRRAQVRDWIKATCWVFSVAVGFFISLNIVQVNVEAVSRRMANLAFCLWVVASSLMLLSCLLLSGIVLSFAKFLIKGALVPCSWKLIQSATTNRQSESLIVEAEKNKPSFCLITALNRNQLFFFLLSNVATGLINLTVDTLHTGAFWTLAVLSIYMFANCLVIYVLDLQGKTIKFW

Gene Information

Entrez Gene ID
378774
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class W
Gene Symbol
Pigw
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005789 IEA:InterPro C endoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016746 IEA:UniProtKB-KW F transferase activity, transferring acyl groups
GO:0006506 IEA:UniProtKB-UniPathway P GPI anchor biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
M00065 GPI-anchor biosynthesis, core oligosaccharide
ko00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
rno00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
rno01100 Metabolic pathways

Domain Information

InterPro Annotations

Accession Description
IPR009447 GWT1

UniProt Annotations

Entry Information

Gene Name
phosphatidylinositol glycan anchor biosynthesis, class W
Protein Entry
PIGW_RAT
UniProt ID
Q7TSN4
Species
Rat

Comments

Comment Type Description
Function Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI- anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins
Pathway Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
Similarity Belongs to the PIGW family
Subcellular Location Endoplasmic reticulum membrane ; Multi-pass membrane protein .

Identical and Related Proteins

Unique RefSeq proteins for LMP013548 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
37360979 RefSeq NP_919443 502 phosphatidylinositol-glycan biosynthesis class W protein

Identical Sequences to LMP013548 proteins

Reference Database Accession Length Protein Name
GI:37360979 DBBJ BAC77020.1 502 phosphatidylinositol glycan, class W [Rattus norvegicus]
GI:37360979 SwissProt Q7TSN4.1 502 RecName: Full=Phosphatidylinositol-glycan biosynthesis class W protein; Short=PIG-W [Rattus norvegicus]

Related Sequences to LMP013548 proteins

Reference Database Accession Length Protein Name
GI:37360979 DBBJ BAC77020.1 502 phosphatidylinositol glycan, class W [Rattus norvegicus]
GI:37360979 RefSeq XP_006247117.1 505 PREDICTED: phosphatidylinositol-glycan biosynthesis class W protein isoform X1 [Rattus norvegicus]
GI:37360979 RefSeq XP_006247118.1 505 PREDICTED: phosphatidylinositol-glycan biosynthesis class W protein isoform X1 [Rattus norvegicus]
GI:37360979 SwissProt Q7TSN4.1 502 RecName: Full=Phosphatidylinositol-glycan biosynthesis class W protein; Short=PIG-W [Rattus norvegicus]