Gene/Proteome Database (LMPD)

LMPD ID
LMP013557
Gene ID
493574
Species
Rattus norvegicus (Rat)
Gene Name
isoprenoid synthase domain containing
Gene Symbol
Ispd
Synonyms
Nip;
Alternate Names
isoprenoid synthase domain-containing protein; notch1-induced protein; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein;
Chromosome
6
Map Location
6q16
EC Number
2.7.7.-

Proteins

isoprenoid synthase domain-containing protein
Refseq ID NP_001008387
Protein GI 56605844
UniProt ID Q5S6T3
mRNA ID NM_001008386
Length 447
MESGPCSRPAEPRHCVSGRAGAGLAFPAFPLSAAGAEPGSRIGTVAAVLPAGGCGERMGVRTPKQFCRVLERPLISYTLQAMERVCWIKDIVVTVTGENMEAMRSIIQRYGHKRISLAEAGATRHRSIFNGLKALAEDQPGCELTRPEVVIIHDAVRPFVEEDILLRVVLAAKEHGAAGAIRPLVSTVVSPSADGHLDHSLDRAKHRASEMPQAFHFDVIYEAYQKCSDFDLEFGTECLQLALKYCHRKAKLVEGTPDLWKVTYKQDLCAAEAMIKEKISQEICVVVNTKDEESVGHLLEEVLRNELNCIKVTSTVLDRTSGDIENFIDQCYSFICVNVVSSESRETRKLLSILEESSLPLLYPVVVVLVHCFDFTVVPLAQKMENLVWIRELAKEAKGRNVLLSGVLLNHSQDEQKLQESLVQSAAIIAALVKERNSALVGQLLVA

Gene Information

Entrez Gene ID
493574
Gene Name
isoprenoid synthase domain containing
Gene Symbol
Ispd
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016779 IEA:UniProtKB-KW F nucleotidyltransferase activity
GO:0007411 IEA:Ensembl P axon guidance
GO:0008299 IEA:InterPro P isoprenoid biosynthetic process
GO:0035269 ISS:UniProtKB P protein O-linked mannosylation

Domain Information

InterPro Annotations

Accession Description
IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site
IPR029044 Nucleotide-diphospho-sugar transferases

UniProt Annotations

Entry Information

Gene Name
isoprenoid synthase domain containing
Protein Entry
ISPD_RAT
UniProt ID
Q5S6T3
Species
Rat

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q5S6T3-1; Sequence=Displayed; Name=2; IsoId=Q5S6T3-2; Sequence=VSP_034674;
Function Required for protein O-linked mannosylation. Probably acts as a nucleotidyltransferase involved in synthesis of a nucleotide sugar. Required for dystroglycan O-mannosylation (By similarity)
Pathway Protein modification; protein glycosylation.
Similarity Belongs to the IspD family

Identical and Related Proteins

Unique RefSeq proteins for LMP013557 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
56605844 RefSeq NP_001008387 447 isoprenoid synthase domain-containing protein

Identical Sequences to LMP013557 proteins

Reference Database Accession Length Protein Name
GI:56605844 GenBank AAV53696.1 447 notch1-induced protein [Rattus norvegicus]
GI:56605844 SwissProt Q5S6T3.1 447 RecName: Full=Isoprenoid synthase domain-containing protein; AltName: Full=2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein; AltName: Full=Notch1-induced protein [Rattus norvegicus]

Related Sequences to LMP013557 proteins

Reference Database Accession Length Protein Name
GI:56605844 GenBank AAV53696.1 447 notch1-induced protein [Rattus norvegicus]
GI:56605844 GenBank AAH86665.1 447 4930579E17Rik protein [Mus musculus]
GI:56605844 SwissProt Q5S6T3.1 447 RecName: Full=Isoprenoid synthase domain-containing protein; AltName: Full=2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein; AltName: Full=Notch1-induced protein [Rattus norvegicus]
GI:56605844 SwissProt Q5RJG7.1 447 RecName: Full=Isoprenoid synthase domain-containing protein; AltName: Full=2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein [Mus musculus]