Gene/Proteome Database (LMPD)

LMPD ID
LMP013563
Gene ID
497931
Species
Rattus norvegicus (Rat)
Gene Name
phosphoinositide-3-kinase, regulatory subunit 5
Gene Symbol
Pik3r5
Synonyms
RGD1563261;
Alternate Names
phosphoinositide 3-kinase regulatory subunit 5; phosphoinositide-3-kinase, regulatory subunit 5, p101;
Chromosome
10
Map Location
10q24

Proteins

phosphoinositide 3-kinase regulatory subunit 5
Refseq ID NP_001178852
Protein GI 300794017
UniProt ID D4A4I3
mRNA ID NM_001191923
Length 872
MQPAATTCTEDRIQHALERCLHGLSLGRRSAPWSAGLCLNCWSLQELVSRDPGHFLILLEQILQKTQEVQEKGTYDLLAPLALLFYSTVLCTPHFPPDSDLLLKAASTYHCFLTWPVPYCSICREMLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVADKLSTPGQSPHGAYTTLLLHAFQATFGTHCDLPKLHRKLQSKTLEELEDIFTETTEAQELASGIGDVAEARQWLRTKLQAVGEKAGFPGILDTASPGKLHTIPIPVARCYTYSWNQDSFDILQEVLLKEQELLQPGILGDDEEEEEEDLEIDRHIAERDSLLSTGSLVSHDSELLLTSSQASGPVLSRQVLTTFVSGLSDGMDSGYVEDSEESSSEWPKKPGSQQRQGHRRPRQKFNRFYKLLKSTSQLVLRRDSRSLECSPDPTLPLRRAGSLSSPLDFPTQLPSRAQRSRSLPQPKLSTQLPSWLLAPPSHHQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSKLRRLENSHPILTRFFKLQFFYVPVKRSHGASSSACLSSLNQASPLLPDSLKHPSPADLGKAPWEDSTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAESRPLEGSATQLPILADMLLYYCRFAARPVLLQVYQTELTFVTGEKTTEIFIQSLELGHSATTRAIKASGPGSKRLGIGDDREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLSKACQKPEELDSSMEALTLTLTEVVKRQNPKSKKGFNQISTSYIKVDKVQIISSSSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKSSLPPEGSLSQPAEAGSDLCSLLCLPIMTFSGALP

Gene Information

Entrez Gene ID
497931
Gene Name
phosphoinositide-3-kinase, regulatory subunit 5
Gene Symbol
Pik3r5
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005942 IDA:RGD C phosphatidylinositol 3-kinase complex
GO:0005944 IEA:InterPro C phosphatidylinositol 3-kinase complex, class IB
GO:0046935 IDA:RGD F 1-phosphatidylinositol-3-kinase regulator activity
GO:0043551 IDA:RGD P regulation of phosphatidylinositol 3-kinase activity

KEGG Pathway Links

KEGG Pathway ID Description
ko05221 Acute myeloid leukemia
rno05221 Acute myeloid leukemia
ko04261 Adrenergic signaling in cardiomyocytes
rno04261 Adrenergic signaling in cardiomyocytes
ko04960 Aldosterone-regulated sodium reabsorption
rno04960 Aldosterone-regulated sodium reabsorption
ko05146 Amoebiasis
rno05146 Amoebiasis
ko04152 AMPK signaling pathway
rno04152 AMPK signaling pathway
ko04210 Apoptosis
rno04210 Apoptosis
ko05100 Bacterial invasion of epithelial cells
rno05100 Bacterial invasion of epithelial cells
ko04662 B cell receptor signaling pathway
rno04662 B cell receptor signaling pathway
ko04024 cAMP signaling pathway
rno04024 cAMP signaling pathway
ko04973 Carbohydrate digestion and absorption
rno04973 Carbohydrate digestion and absorption
ko04022 cGMP-PKG signaling pathway
rno04022 cGMP-PKG signaling pathway
ko05142 Chagas disease (American trypanosomiasis)
rno05142 Chagas disease (American trypanosomiasis)
ko04062 Chemokine signaling pathway
rno04062 Chemokine signaling pathway
rno04725 Cholinergic synapse
ko05220 Chronic myeloid leukemia
rno05220 Chronic myeloid leukemia
ko05210 Colorectal cancer
rno05210 Colorectal cancer
ko05213 Endometrial cancer
rno05213 Endometrial cancer
ko05169 Epstein-Barr virus infection
rno05169 Epstein-Barr virus infection
ko04012 ErbB signaling pathway
rno04012 ErbB signaling pathway
ko04915 Estrogen signaling pathway
rno04915 Estrogen signaling pathway
ko04664 Fc epsilon RI signaling pathway
rno04664 Fc epsilon RI signaling pathway
ko04666 Fc gamma R-mediated phagocytosis
rno04666 Fc gamma R-mediated phagocytosis
ko04510 Focal adhesion
rno04510 Focal adhesion
rno04068 FoxO signaling pathway
ko05214 Glioma
rno05214 Glioma
rno05161 Hepatitis B
ko05160 Hepatitis C
rno05160 Hepatitis C
rno04066 HIF-1 signaling pathway
ko05166 HTLV-I infection
rno05166 HTLV-I infection
ko04750 Inflammatory mediator regulation of TRP channels
rno04750 Inflammatory mediator regulation of TRP channels
ko05164 Influenza A
rno05164 Influenza A
ko04910 Insulin signaling pathway
rno04910 Insulin signaling pathway
ko04630 Jak-STAT signaling pathway
rno04630 Jak-STAT signaling pathway
ko04670 Leukocyte transendothelial migration
rno04670 Leukocyte transendothelial migration
ko05162 Measles
rno05162 Measles
ko05218 Melanoma
rno05218 Melanoma
ko04150 mTOR signaling pathway
rno04150 mTOR signaling pathway
ko04650 Natural killer cell mediated cytotoxicity
rno04650 Natural killer cell mediated cytotoxicity
ko04722 Neurotrophin signaling pathway
rno04722 Neurotrophin signaling pathway
ko04932 Non-alcoholic fatty liver disease (NAFLD)
rno04932 Non-alcoholic fatty liver disease (NAFLD)
ko05223 Non-small cell lung cancer
rno05223 Non-small cell lung cancer
ko04380 Osteoclast differentiation
rno04380 Osteoclast differentiation
ko04921 Oxytocin signaling pathway
rno04921 Oxytocin signaling pathway
ko05212 Pancreatic cancer
rno05212 Pancreatic cancer
rno05200 Pathways in cancer
ko04070 Phosphatidylinositol signaling system
rno04070 Phosphatidylinositol signaling system
ko04151 PI3K-Akt signaling pathway
rno04151 PI3K-Akt signaling pathway
rno04611 Platelet activation
ko04914 Progesterone-mediated oocyte maturation
rno04914 Progesterone-mediated oocyte maturation
ko04917 Prolactin signaling pathway
rno04917 Prolactin signaling pathway
ko05215 Prostate cancer
rno05215 Prostate cancer
ko05205 Proteoglycans in cancer
rno05205 Proteoglycans in cancer
ko04015 Rap1 signaling pathway
rno04015 Rap1 signaling pathway
rno04014 Ras signaling pathway
ko04810 Regulation of actin cytoskeleton
rno04810 Regulation of actin cytoskeleton
ko05211 Renal cell carcinoma
rno05211 Renal cell carcinoma
ko04550 Signaling pathways regulating pluripotency of stem cells
rno04550 Signaling pathways regulating pluripotency of stem cells
ko05222 Small cell lung cancer
rno05222 Small cell lung cancer
ko04660 T cell receptor signaling pathway
rno04660 T cell receptor signaling pathway
rno04919 Thyroid hormone signaling pathway
ko04668 TNF signaling pathway
rno04668 TNF signaling pathway
ko04620 Toll-like receptor signaling pathway
rno04620 Toll-like receptor signaling pathway
ko05145 Toxoplasmosis
rno05145 Toxoplasmosis
ko04930 Type II diabetes mellitus
rno04930 Type II diabetes mellitus
ko04370 VEGF signaling pathway
rno04370 VEGF signaling pathway
ko05203 Viral carcinogenesis
rno05203 Viral carcinogenesis

REACTOME Pathway Links

REACTOME Pathway ID Description
5954002 G beta:gamma signalling through PI3Kgamma
5953642 GPCR downstream signaling
5954003 G-protein beta:gamma signalling
5953651 GPVI-mediated activation cascade
5953645 Hemostasis
5953250 Metabolism
5953289 Metabolism of lipids and lipoproteins
5953474 Phospholipid metabolism
5954478 PI Metabolism
5953644 Platelet activation, signaling and aggregation
5953391 Signaling by GPCR
5953381 Signal Transduction
5954499 Synthesis of PIPs at the plasma membrane

Domain Information

InterPro Annotations

Accession Description
IPR019522 Phosphoinositide 3-kinase regulatory subunit 5/6

UniProt Annotations

Entry Information

Gene Name
phosphoinositide-3-kinase, regulatory subunit 5
Protein Entry
D4A4I3_RAT
UniProt ID
D4A4I3
Species
Rat

Identical and Related Proteins

Unique RefSeq proteins for LMP013563 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
300794017 RefSeq NP_001178852 872 phosphoinositide 3-kinase regulatory subunit 5

Identical Sequences to LMP013563 proteins

Reference Database Accession Length Protein Name
GI:300794017 RefSeq XP_006246832.1 872 PREDICTED: phosphoinositide 3-kinase regulatory subunit 5 isoform X1 [Rattus norvegicus]

Related Sequences to LMP013563 proteins

Reference Database Accession Length Protein Name
GI:300794017 GenBank ABK42308.1 871 phosphoinositide 3-kinase p101 class Ib regulatory subunit [synthetic construct]
GI:300794017 GenBank AAI28077.1 871 Phosphoinositide-3-kinase, regulatory subunit 5, p101 [Mus musculus]
GI:300794017 GenBank AAI28078.1 871 Phosphoinositide-3-kinase, regulatory subunit 5, p101 [Mus musculus]
GI:300794017 RefSeq XP_006246832.1 872 PREDICTED: phosphoinositide 3-kinase regulatory subunit 5 isoform X1 [Rattus norvegicus]