Gene/Proteome Database (LMPD)

LMPD ID
LMP013615
Gene ID
652927
Species
Rattus norvegicus (Rat)
Gene Name
ABO-family member 5
Gene Symbol
Ggta1
Synonyms
Glt6d1; Ggta1l1;
Alternate Names
N-acetyllactosaminide alpha-1,3-galactosyltransferase; galactosyltransferase; ABO-family member protein 5; glycosyltransferase 6 domain-containing protein 1; UDP-galactose:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase;
Chromosome
3
Map Location
3q11-q12
EC Number
2.4.1.87;

Proteins

N-acetyllactosaminide alpha-1,3-galactosyltransferase precursor
Refseq ID NP_001032672
Protein GI 83035141
UniProt ID G3V9Q9
mRNA ID NM_001037583
Length 321
MQYKKETLLLILLAILLALTQRYSRTKDHLQKMYTCWRDHLEEPQLESWFNPKKRPDVIATTGWLAPVLWEGTYDREVLEQYYKRLNITVGLAVFATGNFSSESLRRFIKSANKYFMVGYNVIFYILADGTSNLPYLELGPLRTLKMWRLSGEEMTYEDSNLRNMNNMRYKIMEHIQYEVNFLFVMTANQIIKSHFGVETLGRSVAQLHAWWYFKQPREFPYERRRKASAFIAFEEGDFYYHSAIVGGTPLDVLDLIEHYIKGIIDDRTNELSSTYERHLNKYFFIKKPVRVLSPEYNWDPRFKTPPEIWHIKVAWQPRIT
sig_peptide: 1..22 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2586 peptide sequence: MQYKKETLLLILLAILLALTQR

Gene Information

Entrez Gene ID
652927
Gene Name
ABO-family member 5
Gene Symbol
Ggta1
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:UniProtKB-KW C Golgi apparatus
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0047276 IEA:UniProtKB-EC F N-acetyllactosaminide 3-alpha-galactosyltransferase activity
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0006486 IEA:UniProtKB-UniPathway P protein glycosylation

Domain Information

InterPro Annotations

Accession Description
IPR005076 Glycosyl transferase, family 6
IPR029044 Nucleotide-diphospho-sugar transferases

UniProt Annotations

Entry Information

Gene Name
ABO-family member 5
Protein Entry
GTA1L_RAT
UniProt ID
G3V9Q9
Species
Rat

Comments

Comment Type Description
Catalytic Activity UDP-alpha-D-galactose + beta-D-galactosyl- (1->4)-beta-N-acetyl-D-glucosaminyl-R = UDP + alpha-D-galactosyl- (1->3)-beta-D-galactosyl-(1->4)-beta-N-acetylglucosaminyl-R.
Cofactor Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence= ;
Domain The conserved DXD motif is involved in cofactor binding. The manganese ion interacts with the beta-phosphate group of UDP and may also have a role in catalysis (By similarity)
Function Synthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on terminal lactosaminide (Gal-beta-1,4-GlcNAc-R) disaccharide borne by a glycoprotein or a glycolipid
Miscellaneous This gene is not expressed in humans.
Pathway Protein modification; protein glycosylation.
Similarity Belongs to the glycosyltransferase 6 family
Subcellular Location Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein . Note=Membrane-bound form in trans cisternae of Golgi

Identical and Related Proteins

Unique RefSeq proteins for LMP013615 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
83035141 RefSeq NP_001032672 321 N-acetyllactosaminide alpha-1,3-galactosyltransferase precursor

Identical Sequences to LMP013615 proteins

Reference Database Accession Length Protein Name
GI:83035141 GenBank AAS92273.1 321 ABO-family member 5 [Rattus norvegicus]

Related Sequences to LMP013615 proteins

Reference Database Accession Length Protein Name
GI:83035141 GenBank AAS92273.1 321 ABO-family member 5 [Rattus norvegicus]
GI:83035141 GenBank EDL93145.1 321 rCG45771 [Rattus norvegicus]
GI:83035141 RefSeq XP_006234108.1 321 PREDICTED: N-acetyllactosaminide alpha-1,3-galactosyltransferase isoform X1 [Rattus norvegicus]
GI:83035141 SwissProt G3V9Q9.1 321 RecName: Full=N-acetyllactosaminide alpha-1,3-galactosyltransferase-like 1 [Rattus norvegicus]