Gene/Proteome Database (LMPD)

LMPD ID
LMP013939
Gene ID
718301
Species
Macaca mulatta (Rhesus monkey)
Gene Name
COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)
Gene Symbol
COX10
Alternate Names
protoheme IX farnesyltransferase, mitochondrial;
Chromosome
16
Map Location
chromosome:16
EC Number
2.5.1.-

Proteins

protoheme IX farnesyltransferase, mitochondrial
Refseq ID NP_001181573
Protein GI 302564578
UniProt ID F7FTL6
mRNA ID NM_001194644
Length 443
Protein sequence is identical to GI:109113374 (mRNA isoform)
Refseq ID XP_001114525
Protein GI 109113374
UniProt ID F7FTL6
mRNA ID XM_001114525
Length 443
MAASPHTLSSRLLAGWVGGCVWYLKRRTIQESPHKFLHLFRNVNKRWITFQHFSFLKRMYVTQLNRSHNQQVKPKPEPVASPFLEKTSSGQAKAEMYEMRPLSAPSLSLSRKPNEKELIELEPASVIEDSIDVRKETKEEKRWKEMKLQVYDLPGILARLSKIKLTGLVVSTTAAGFALAPGPFDWPCFLLASVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVAFATCCAVPGVAILTWGVNPLTGALGLFNIFLYTCCYTPLKRISIVNTWVGAVVGAIPPVMGWTAATGSLDAGAFLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPFVALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLPLLLLLMLTCKRPRGDEDAAPPPS

Gene Information

Entrez Gene ID
718301
Gene Name
COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)
Gene Symbol
COX10
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:InterPro C integral component of membrane
GO:0031966 IEA:UniProtKB-SubCell C mitochondrial membrane
GO:0004129 IEA:Ensembl F cytochrome-c oxidase activity
GO:0008495 IEA:InterPro F protoheme IX farnesyltransferase activity
GO:0009060 IEA:Ensembl P aerobic respiration
GO:0048034 IEA:InterPro P heme O biosynthetic process
GO:0006784 IEA:Ensembl P heme a biosynthetic process
GO:0000266 IEA:Ensembl P mitochondrial fission
GO:0008535 IEA:Ensembl P respiratory chain complex IV assembly

KEGG Pathway Links

KEGG Pathway ID Description
M00154 Cytochrome c oxidase
mcc_M00154 Cytochrome c oxidase
mcc01100 Metabolic pathways
ko00190 Oxidative phosphorylation
mcc00190 Oxidative phosphorylation
ko00860 Porphyrin and chlorophyll metabolism
mcc00860 Porphyrin and chlorophyll metabolism

Domain Information

InterPro Annotations

Accession Description
IPR006369 Protohaem IX farnesyltransferase
IPR016315 Protohaem IX farnesyltransferase, mitochondria
IPR000537 UbiA prenyltransferase family

UniProt Annotations

Entry Information

Gene Name
COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)
Protein Entry
F7FTL6_MACMU
UniProt ID
F7FTL6
Species
Rhesus monkey

Comments

Comment Type Description
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Function Converts protoheme IX and farnesyl diphosphate to heme O.
Similarity Belongs to the ubiA prenyltransferase family.
Subcellular Location Mitochondrion membrane

Identical and Related Proteins

Unique RefSeq proteins for LMP013939 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109113374 RefSeq XP_001114525 443 COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)

Identical Sequences to LMP013939 proteins

Reference Database Accession Length Protein Name
GI:302564578 GenBank EHH57752.1 443 Protoheme IX farnesyltransferase, mitochondrial [Macaca fascicularis]

Related Sequences to LMP013939 proteins

Reference Database Accession Length Protein Name
GI:302564578 GenBank EHH24552.1 443 Protoheme IX farnesyltransferase, mitochondrial [Macaca mulatta]
GI:302564578 RefSeq XP_003912422.1 443 PREDICTED: LOW QUALITY PROTEIN: protoheme IX farnesyltransferase, mitochondrial [Papio anubis]
GI:302564578 RefSeq XP_005582996.1 443 PREDICTED: protoheme IX farnesyltransferase, mitochondrial-like isoform X1 [Macaca fascicularis]