Gene/Proteome Database (LMPD)

LMPD ID
LMP013970
Gene ID
717020
Species
Macaca mulatta (Rhesus monkey)
Gene Name
cytochrome P450, family 21, subfamily A, polypeptide 2
Gene Symbol
CYP21A2
Alternate Names
steroid 21-hydroxylase;
Chromosome
4
Map Location
chromosome:4

Proteins

steroid 21-hydroxylase precursor
Refseq ID NP_001181556
Protein GI 302564407
UniProt ID F6RRZ9
mRNA ID NM_001194627
Length 495
Protein sequence is identical to GI:109070555 (mRNA isoform)
sig_peptide: 1..16 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1668 peptide sequence: MLFLGLLLLLPLLAGA
Refseq ID XP_001114183
Protein GI 109070557
UniProt ID F6RK47
mRNA ID XM_001114240
Length 465
MLFLGLLLLLPLLAGARLLWNRWKLRSLHLPPLVPGFLHLLQPDLPIYLLGLTQKFGPIYRLHLGLQDKLVSKNYPDLSLGDYSLLWKAHKKLTRSALLLGMRDSMEPVVEQLTQEFCERMRAQAGTPVAIEEEFSLLTCSIICHLTFGDKIKEDNLVPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFFPNPGLRRLKQAIEKRDHIVEKQLRQHKESLVAGQWRDMMDYMLQVVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPSASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDEMVWERPHEFWPDRFLEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPPGDALPSLQPLPHCSVILKMQPFQVWLQPRGLGVHSLGQSQ
sig_peptide: 1..16 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1668 peptide sequence: MLFLGLLLLLPLLAGA
Refseq ID XP_001114240
Protein GI 109070555
UniProt ID F6RRZ9
mRNA ID XM_001114240
Length 495
MLFLGLLLLLPLLAGARLLWNRWKLRSLHLPPLVPGFLHLLQPDLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYPDLSLGDYSLLWKAHKKLTRSALLLGMRDSMEPVVEQLTQEFCERMRAQAGTPVAIEEEFSLLTCSIICHLTFGDKIKEDNLVPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFFPNPGLRRLKQAIEKRDHIVEKQLRQHKESLVAGQWRDMMDYMLQVVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPSASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDEMVWERPHEFWPDRFLEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPPGDALPSLQPLPHCSVILKMQPFQVWLQPRGLGVHSLGQSQ
sig_peptide: 1..16 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1668 peptide sequence: MLFLGLLLLLPLLAGA

Gene Information

Entrez Gene ID
717020
Gene Name
cytochrome P450, family 21, subfamily A, polypeptide 2
Gene Symbol
CYP21A2
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0020037 IEA:InterPro F heme binding
GO:0005506 IEA:InterPro F iron ion binding
GO:0004497 IEA:UniProtKB-KW F monooxygenase activity
GO:0016705 IEA:InterPro F oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

KEGG Pathway Links

KEGG Pathway ID Description
M00108 C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone
mcc_M00108 C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone
M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
mcc_M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
mcc01100 Metabolic pathways
ko00140 Steroid hormone biosynthesis
mcc00140 Steroid hormone biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR001128 Cytochrome P450
IPR002401 Cytochrome P450, E-class, group I
IPR017972 Cytochrome P450, conserved site

UniProt Annotations

Entry Information

Gene Name
cytochrome P450, family 21, subfamily A, polypeptide 2
Protein Entry
F6RRZ9_MACMU
UniProt ID
F6RRZ9
Species
Rhesus monkey

Comments

Comment Type Description
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Similarity Belongs to the cytochrome P450 family.

Identical and Related Proteins

Unique RefSeq proteins for LMP013970 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109070555 RefSeq XP_001114240 495 cytochrome P450, family 21, subfamily A, polypeptide 2
109070557 RefSeq XP_001114183 465 cytochrome P450, family 21, subfamily A, polypeptide 2

Identical Sequences to LMP013970 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP013970 proteins

Reference Database Accession Length Protein Name
GI:302564407 DBBJ BAG37212.1 495 unnamed protein product [Homo sapiens]
GI:302564407 GenBank EAX03571.1 495 cytochrome P450, family 21, subfamily A, polypeptide 2, isoform CRA_b [Homo sapiens]
GI:302564407 RefSeq XP_005553488.1 495 PREDICTED: steroid 21-hydroxylase-like isoform X1 [Macaca fascicularis]
GI:302564407 RefSeq XP_007971226.1 495 PREDICTED: steroid 21-hydroxylase isoform X1 [Chlorocebus sabaeus]