Gene/Proteome Database (LMPD)

LMPD ID
LMP013973
Gene ID
715747
Species
Macaca mulatta (Rhesus monkey)
Gene Name
cytochrome P450, family 27, subfamily B, polypeptide 1
Gene Symbol
CYP27B1
Alternate Names
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial;
Chromosome
11
Map Location
chromosome:11

Proteins

25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
Refseq ID NP_001181642
Protein GI 302565222
UniProt ID F7H3A6
mRNA ID NM_001194713
Length 508
Protein sequence is identical to GI:109097519 (mRNA isoform)
Refseq ID XP_001116450
Protein GI 109097519
UniProt ID F7H3A6
mRNA ID XM_001116450
Length 508
MTQTLKYASRVFHRVRWAPELGASLGYREYDSARRSLADIPGPSTPSFLAELFCKGGLSRLHELQVQGAARFGPVWLASFGTVRTVYVAAPALVEELLRQEGPRPERCSFSPWTEHRRRRQRACGLLTAEGEEWQRLRSLLAPLLLRPQAAARYAETLDNVVRDLVRRLRCQRGRGTGPPALVRDVAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPDTETFIRAVGSVFVSTLLTMAMPHWLRRLVPGPWGRLCRDWDQMFAFAQRHVERREAEAAMRNRGQPDEDLESGAHLTHFLFQEELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALGPGSSAHPPATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFHPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILIHFEVQPEPGAAPIRPMTRTVLVPERSINLQFLDR

Gene Information

Entrez Gene ID
715747
Gene Name
cytochrome P450, family 27, subfamily B, polypeptide 1
Gene Symbol
CYP27B1
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IEA:Ensembl C mitochondrion
GO:0004498 IEA:Ensembl F calcidiol 1-monooxygenase activity
GO:0020037 IEA:InterPro F heme binding
GO:0005506 IEA:InterPro F iron ion binding
GO:0070314 IEA:Ensembl P G1 to G0 transition
GO:0030282 IEA:Ensembl P bone mineralization
GO:0055074 IEA:Ensembl P calcium ion homeostasis
GO:0006816 IEA:Ensembl P calcium ion transport
GO:0046697 IEA:Ensembl P decidualization
GO:0010956 IEA:Ensembl P negative regulation of calcidiol 1-monooxygenase activity
GO:0030308 IEA:Ensembl P negative regulation of cell growth
GO:0008285 IEA:Ensembl P negative regulation of cell proliferation
GO:0045618 IEA:Ensembl P positive regulation of keratinocyte differentiation
GO:0010980 IEA:Ensembl P positive regulation of vitamin D 24-hydroxylase activity
GO:0070564 IEA:Ensembl P positive regulation of vitamin D receptor signaling pathway
GO:0030500 IEA:Ensembl P regulation of bone mineralization
GO:0043627 IEA:Ensembl P response to estrogen
GO:0034341 IEA:Ensembl P response to interferon-gamma
GO:0032496 IEA:Ensembl P response to lipopolysaccharide
GO:0033280 IEA:Ensembl P response to vitamin D
GO:0042369 IEA:Ensembl P vitamin D catabolic process

KEGG Pathway Links

KEGG Pathway ID Description
M00103 Cholecalciferol biosynthesis
mcc_M00103 Cholecalciferol biosynthesis
mcc01100 Metabolic pathways
ko00100 Steroid biosynthesis
mcc00100 Steroid biosynthesis
ko05152 Tuberculosis
mcc05152 Tuberculosis

Domain Information

InterPro Annotations

Accession Description
IPR001128 Cytochrome P450
IPR002401 Cytochrome P450, E-class, group I
IPR017972 Cytochrome P450, conserved site

UniProt Annotations

Entry Information

Gene Name
cytochrome P450, family 27, subfamily B, polypeptide 1
Protein Entry
F7H3A6_MACMU
UniProt ID
F7H3A6
Species
Rhesus monkey

Identical and Related Proteins

Unique RefSeq proteins for LMP013973 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109097519 RefSeq XP_001116450 508 cytochrome P450, family 27, subfamily B, polypeptide 1

Identical Sequences to LMP013973 proteins

Reference Database Accession Length Protein Name
GI:302565222 GenBank EHH20910.1 508 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial [Macaca mulatta]
GI:302565222 RefSeq XP_005571445.1 508 PREDICTED: 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial-like [Macaca fascicularis]

Related Sequences to LMP013973 proteins

Reference Database Accession Length Protein Name
GI:302565222 RefSeq XP_003906736.1 508 PREDICTED: 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial isoform X2 [Papio anubis]
GI:302565222 RefSeq XP_008002032.1 508 PREDICTED: 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial [Chlorocebus sabaeus]