Gene/Proteome Database (LMPD)

LMPD ID
LMP013989
Gene ID
698127
Species
Macaca mulatta (Rhesus monkey)
Gene Name
cytochrome P450, family 7, subfamily A, polypeptide 1
Gene Symbol
CYP7A1
Alternate Names
cholesterol 7-alpha-monooxygenase;
Chromosome
8
Map Location
chromosome:8

Proteins

cholesterol 7-alpha-monooxygenase
Refseq ID NP_001180732
Protein GI 302563835
UniProt ID F7HS30
mRNA ID NM_001193803
Length 504
Protein sequence is identical to GI:109086484 (mRNA isoform)
Refseq ID XP_001087135
Protein GI 109086484
UniProt ID F7HS30
mRNA ID XM_001087135
Length 504
MMTISLIWGIAIAACCCLWLILGIRRRQTGEPPLENGLIPYLGCALQFGANPLEFLRANQRKHGHVFTCKLMGKYVHFITNPLSYHKVLCHGKYFDWKKFHFATSAKAFGHRSIDPKDGNTTENINNTFIKTLQGNALNSLTESMMENLQRIMRPPVFSNSKTAAWVTEGMYSFCYRVMFEAGYLTIFGRDLTRQDTQKAHILNNLDNFKQFDKVFPALVAGLPIHMFRTAHSAREKLAESLRHENLQKRESVSELIRLRMFLNDTLSTFDDLEKAKTHLVVLWASQANTIPATFWSLFQMIRNPEAMKAATEEVKRTLENAGQKVSLEGNPICLSQTQLNDLPVLESIIKESLRLSSASLNIRTAKEDFTLHLEEGSYNIRKDDIIALYPQLMHLDPEIYPDPLSFKYDRYLDENGKTKTTFYCNGLKLKYYYMPFGSGATICPGRVFAIHEIKQFLVLMLSYFELELVEGQDKCPPLDQSRAGLGILPPLYDIEFKYKFKHL

Gene Information

Entrez Gene ID
698127
Gene Name
cytochrome P450, family 7, subfamily A, polypeptide 1
Gene Symbol
CYP7A1
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005789 IEA:UniProtKB-SubCell C endoplasmic reticulum membrane
GO:0020037 IEA:InterPro F heme binding
GO:0005506 IEA:InterPro F iron ion binding
GO:0004497 IEA:UniProtKB-KW F monooxygenase activity
GO:0016705 IEA:InterPro F oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0071333 IEA:Ensembl P cellular response to glucose stimulus

KEGG Pathway Links

KEGG Pathway ID Description
ko04976 Bile secretion
mcc04976 Bile secretion
mcc01100 Metabolic pathways
ko03320 PPAR signaling pathway
mcc03320 PPAR signaling pathway
ko00120 Primary bile acid biosynthesis
mcc00120 Primary bile acid biosynthesis
ko00140 Steroid hormone biosynthesis
mcc00140 Steroid hormone biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR001128 Cytochrome P450
IPR002403 Cytochrome P450, E-class, group IV
IPR024204 Cytochrome P450, cholesterol 7-alpha-monooxygenase-type
IPR017972 Cytochrome P450, conserved site

UniProt Annotations

Entry Information

Gene Name
cytochrome P450, family 7, subfamily A, polypeptide 1
Protein Entry
F7HS30_MACMU
UniProt ID
F7HS30
Species
Rhesus monkey

Comments

Comment Type Description
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Cofactor Note=Heme group. {ECO:0000256|PIRNR:PIRNR000047, ECO:0000256|PIRSR:PIRSR000047-1};
Similarity Belongs to the cytochrome P450 family.
Subcellular Location Endoplasmic reticulum membrane

Identical and Related Proteins

Unique RefSeq proteins for LMP013989 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109086484 RefSeq XP_001087135 504 cytochrome P450, family 7, subfamily A, polypeptide 1

Identical Sequences to LMP013989 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP013989 proteins

Reference Database Accession Length Protein Name
GI:302563835 GenBank EHH28524.1 504 Cholesterol 7-alpha-monooxygenase [Macaca mulatta]
GI:302563835 GenBank EHH64186.1 504 Cholesterol 7-alpha-monooxygenase [Macaca fascicularis]
GI:302563835 RefSeq XP_005563427.1 504 PREDICTED: cholesterol 7-alpha-monooxygenase-like [Macaca fascicularis]
GI:302563835 RefSeq XP_007998894.1 504 PREDICTED: cholesterol 7-alpha-monooxygenase [Chlorocebus sabaeus]