Gene/Proteome Database (LMPD)

LMPD ID
LMP014049
Gene ID
699575
Species
Macaca mulatta (Rhesus monkey)
Gene Name
eukaryotic translation initiation factor 2-alpha kinase 3
Gene Symbol
EIF2AK3
Alternate Names
eukaryotic translation initiation factor 2-alpha kinase 3;
Chromosome
13
Map Location
chromosome:13

Proteins

Refseq ID XP_001094377
Protein GI 297266495
UniProt ID F7H8D0
mRNA ID XM_001094493
Length 1076
MDCGRGARPWPPSTSATRVPAAGAVAAAEVTVEDAEALPAAAGEQEPRGPEPDDEAELPPRGRSLVIISTLDGRIAALDPENHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGALFQWDRDRESMETVPFTVESLLESSYKFGDDVVLVGGKSLTTYGLSACSGKVRYICSALGCRQWDSDEMEQEEDILLVQRTQKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTFKPNENTEESKIISDVEEQEAAIMDIVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLLKDGKVIPISLFDDTSYTSNDDVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPTSPKALESVNNENAIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYYLPYYKRERNKRSTQITVRFLDNPNYNKNIRKKDPVLLLHWWKEIVATILFCIIATTFIVRRLFHPHPHRQRKESETQCQTENKYDSVSGEANDSNWNDIKNSGYVSRYLTDFEPIQCLGRGGFGVVFEAKNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEAPPEKWQEKMDEIWLKDASTDWPLSSPSPMDAPSVKIRRMDPFSTKEHVEIIAPSPERSRSFSVGISCDQTSSSESQFSPLEFSGMDHEDISESVDAAYNLQDSCLTDCDVEDGTMDGNDEGHSFELCPSEASPYVRSRERTSSSIVFEDSGCDNASSKEEPKTNRLHIGNHCANKLTAFKPTSSKSSSEATLSISPPRPTTLSLDLTKNTTEKLQPSSPKVYLYIQMQLCRKENLKDWMNGRCTIEERERSMCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQDEEEQTVLTPMPAYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFEILYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCEYMMVQDMLSPSPMERPEATNIIENAVFEDLDFPGKTVLRQRSRSLSSSGTKHSRQSNNSHSPLPSN
Refseq ID XP_001094493
Protein GI 109103770
UniProt ID F7H8D0
mRNA ID XM_001094493
Length 1115
MERATRPGLLVLALLLPLLLGLAAWTVAAGRARGLPAPTAEAAFGLGAAAAPTSATRVPAAGAVAAAEVTVEDAEALPAAAGEQEPRGPEPDDEAELPPRGRSLVIISTLDGRIAALDPENHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGALFQWDRDRESMETVPFTVESLLESSYKFGDDVVLVGGKSLTTYGLSACSGKVRYICSALGCRQWDSDEMEQEEDILLVQRTQKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTFKPNENTEESKIISDVEEQEAAIMDIVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLLKDGKVIPISLFDDTSYTSNDDVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPTSPKALESVNNENAIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYYLPYYKRERNKRSTQITVRFLDNPNYNKNIRKKDPVLLLHWWKEIVATILFCIIATTFIVRRLFHPHPHRQRKESETQCQTENKYDSVSGEANDSNWNDIKNSGYVSRYLTDFEPIQCLGRGGFGVVFEAKNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEAPPEKWQEKMDEIWLKDASTDWPLSSPSPMDAPSVKIRRMDPFSTKEHVEIIAPSPERSRSFSVGISCDQTSSSESQFSPLEFSGMDHEDISESVDAAYNLQDSCLTDCDVEDGTMDGNDEGHSFELCPSEASPYVRSRERTSSSIVFEDSGCDNASSKEEPKTNRLHIGNHCANKLTAFKPTSSKSSSEATLSISPPRPTTLSLDLTKNTTEKLQPSSPKVYLYIQMQLCRKENLKDWMNGRCTIEERERSMCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAMDQDEEEQTVLTPMPAYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFEILYPFSTQMERVRTLTDVRNLKFPPLFTQKYPCEYMMVQDMLSPSPMERPEATNIIENAVFEDLDFPGKTVLRQRSRSLSSSGTKHSRQSNNSHSPLPSN

Gene Information

Entrez Gene ID
699575
Gene Name
eukaryotic translation initiation factor 2-alpha kinase 3
Gene Symbol
EIF2AK3
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005789 IEA:Ensembl C endoplasmic reticulum membrane
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0004694 IEA:Ensembl F eukaryotic translation initiation factor 2alpha kinase activity
GO:0006983 IEA:Ensembl P ER overload response
GO:0032933 IEA:Ensembl P SREBP signaling pathway
GO:0006919 IEA:Ensembl P activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0030282 IEA:Ensembl P bone mineralization
GO:0019722 IEA:Ensembl P calcium-mediated signaling
GO:0002063 IEA:Ensembl P chondrocyte development
GO:0031018 IEA:Ensembl P endocrine pancreas development
GO:0007029 IEA:Ensembl P endoplasmic reticulum organization
GO:0030968 IEA:Ensembl P endoplasmic reticulum unfolded protein response
GO:0045444 IEA:Ensembl P fat cell differentiation
GO:0048009 IEA:Ensembl P insulin-like growth factor receptor signaling pathway
GO:0070059 IEA:Ensembl P intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0007595 IEA:Ensembl P lactation
GO:0043066 IEA:Ensembl P negative regulation of apoptotic process
GO:0010629 IEA:Ensembl P negative regulation of gene expression
GO:0031642 IEA:Ensembl P negative regulation of myelination
GO:0017148 IEA:Ensembl P negative regulation of translation
GO:0032092 IEA:Ensembl P positive regulation of protein binding
GO:0009967 IEA:Ensembl P positive regulation of signal transduction
GO:0046777 IEA:Ensembl P protein autophosphorylation
GO:0051260 IEA:Ensembl P protein homooligomerization
GO:0019217 IEA:Ensembl P regulation of fatty acid metabolic process
GO:0006412 IEA:Ensembl P translation

KEGG Pathway Links

KEGG Pathway ID Description
ko05010 Alzheimer's disease
mcc05010 Alzheimer's disease
ko05169 Epstein-Barr virus infection
mcc05169 Epstein-Barr virus infection
ko05160 Hepatitis C
mcc05160 Hepatitis C
ko05168 Herpes simplex infection
mcc05168 Herpes simplex infection
ko05164 Influenza A
mcc05164 Influenza A
ko05162 Measles
mcc05162 Measles
ko04932 Non-alcoholic fatty liver disease (NAFLD)
mcc04932 Non-alcoholic fatty liver disease (NAFLD)
ko04141 Protein processing in endoplasmic reticulum
mcc04141 Protein processing in endoplasmic reticulum

Domain Information

InterPro Annotations

Accession Description
IPR018391 PQQ_beta_propeller_repeat
IPR000719 Protein kinase domain
IPR017441 Protein kinase, ATP binding site
IPR011009 Protein kinase-like domain
IPR011047 Quinonprotein alcohol dehydrogenase-like superfamily
IPR027295 Quinonprotein_ADH-like_fam
IPR008271 Serine/threonine-protein kinase, active site

UniProt Annotations

Entry Information

Gene Name
eukaryotic translation initiation factor 2-alpha kinase 3
Protein Entry
F7H8D0_MACMU
UniProt ID
F7H8D0
Species
Rhesus monkey

Identical and Related Proteins

Unique RefSeq proteins for LMP014049 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109103770 RefSeq XP_001094493 1115 eukaryotic translation initiation factor 2-alpha kinase 3
297266495 RefSeq XP_001094377 1076 eukaryotic translation initiation factor 2-alpha kinase 3

Identical Sequences to LMP014049 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP014049 proteins

Reference Database Accession Length Protein Name
GI:297266495 RefSeq XP_003908998.1 1115 PREDICTED: eukaryotic translation initiation factor 2-alpha kinase 3 [Papio anubis]
GI:297266495 RefSeq XP_005575399.1 1115 PREDICTED: eukaryotic translation initiation factor 2-alpha kinase 3 [Macaca fascicularis]
GI:297266495 RefSeq XP_008006659.1 1115 PREDICTED: eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1 [Chlorocebus sabaeus]
GI:297266495 RefSeq XP_010376742.1 1115 PREDICTED: eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1 [Rhinopithecus roxellana]